Biosensor engineer & transporter aficionado. Cyclist, mountaineer and chef in my free time. scholar.google.com/citations…
Joined March 2019
- Tweets 85
- Following 741
- Followers 178
- Likes 1,050
1 Photos and videos
Philipp Leippe retweeted
19 May 2025
🔬 Breakthrough in cellular logistics!
After a decade of global research, 4 new studies led by Giulio Superti-Furga @ CeMM decode how cells transport chemicals, doubling knowledge on SLCs.
➡️ Read more: bit.ly/4krqBTj
🧬 Open-access tools data: bit.ly/3SDqtmJ
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Philipp Leippe retweeted
23 Apr 2025
„In bedrohlichen Situationen, etwa, als Männer in einer Straßenbahn darüber sprachen, wie sie ihn verprügeln wollten, habe ihm keiner zur Seite gestanden.“
Wir leben in einer Kultur des Wegschauens und brauchen eine Kultur des Hinschauens.
faz.net/aktuell/politik/inla…
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Philipp Leippe retweeted
23 Feb 2025
A single injection of a drug, called lenacapavir, protects 96-100 percent of recipients from HIV for up to six months.
It's the best HIV preventive ever made. To close out Issue 05, @KLNahas explains how Gilead made it & why getting it to those who need it will not be simple.🔻
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17 Nov 2024
X has become an insufferable shithole. Same handle on the other platform!
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Philipp Leippe retweeted
30 Oct 2024
Cell-Specific Optical Control of AMPA Glutamate Receptors with a Photoswitchable Tethered Antagonist (Dirk Trauner and co-workers) @DonthamsettiLab, @VandyPharm, @Pleippe, @DirkTrauner #OpenAccess onlinelibrary.wiley.com/doi/…
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17 Oct 2024
This is incredibly useful! For me, it's a go-to resource for every SLC project and also invaluable for a systems perspective
17 Oct 2024
Are you curious what is known about SLCs? And how they are related? We are enthusiastic to wrap up the series of four (4) manuscripts by presenting the data- and knowledge-derived functional landscape of human solute carriers #SLC : biorxiv.org/content/10.1101/…
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10 Oct 2024
Happy to share our massive (>1Mio guides) functional genomics study on genetic interactions of SLC transporters by Wolf & Leippe et al.! 🧬 Particularly amazed by how the TCA cycle interactions perfectly mirror known biology! What a journey with the CRISPRator✂️ @wolf_gernot! 🙏
9 Oct 2024
We are thrilled to share the THIRD study of our series which sheds light on the genetic interactions between transporters and links them to the metabolic network: doi.org/10.1101/2024.10.07.6…
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Philipp Leippe retweeted
2 Oct 2024
Do you want to know with which proteins an SLC membrane transporter socializes? Our @RESOLUTE_IMI series of 4 manuscripts continues, and we are excited to share the so far most comprehensive interactome mapping of solute carriers biorxiv.org/content/10.1101/…
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Philipp Leippe retweeted
25 Sep 2024
We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (biorxiv.org/content/10.1101/…)!
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Philipp Leippe retweeted
23 Sep 2024
Finally! It is happening! After 6 years of hard work by formidable teams in 13 institutions @RESOLUTE_IMI, we have ordered and validated the results and are able to share the FOUR (4) papers aimed at assigning functional properties to each human SLC #membranetransporter
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Philipp Leippe retweeted
27 Aug 2024
Thank you for attending the 31st BioOrganik symposium last week in Dortmund, a pre-tenure PI networking conference in the mainly German (bio)organic chemistry sphere, jointly organised with @GalstyanLab @PeterChemBio1 @Wiesenfeldt_Lab @kreidtscience @Johannes_Karges SidneyBecker
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27 Aug 2024
happy to see this out, great study! kudos to everyone involved @DirkTrauner @IsacoffLab @VandyPharm
27 Aug 2024
Check out our latest work on Tethered Photopharmacology: Cell‐Specific Optical Control of AMPA Glutamate Receptors with a Photoswitchable Tethered Antagonist @PLeippe @IsacoffLab @VandyPharm onlinelibrary.wiley.com/doi/…
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Philipp Leippe retweeted
28 May 2024
Online now! AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells by Lars Hellweg, Kai Johnsson, @PLeippe, and colleagues at @EPFL_en @mpi_mr_hd @CeMM_News dlvr.it/T7Vyjf #chembiol
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27 May 2024
Very happy and proud to finally see our work on the development the aspartate biosensor AspSnFR published. This was a long and tricky one in the making. The paper is a nice mix of biosensor development and broad applications. 1/2
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27 May 2024
Especially happy that we were able to detect Ca2 triggered aspartate export via SLC25A12 from mitochondria in live HCT116 cells. Thanks to everyone involved! doi.org/10.1016/j.chembiol.2… 2/2 @mpi_mr_hd @RESOLUTE_IMI @CeMM_News @giuliosf
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Philipp Leippe retweeted
🚨 @ScienceMagazine paper alert 👉 A novel chemical labeling method allows transient events in cells to be recorded for later analysis. Congrats to @magnus_huppertz and Jonas Wilhelm and their collaboration partners @MPIforBI, @DKFZ and @HHMIJanelia!
mr.mpg.de/14594969/recording…
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Philipp Leippe retweeted
We are out of words... We are grateful to our fantastic speakers, poster presenters, SAB members and participants, that joined us during the last @IHIEurope RESOLUTE conference in #Vienna. We are sure they will #CarryTheTorch for future research on molecular #transporters.
29 Sep 2023
On 27-29 September 2023, the @RESOLUTE_IMI & REsolution Final Conference took place in Vienna 🇦🇹! ~200 participants gathered to listen to top global #SLCs experts, learn more about the project's results & engage in meaningful scientific discussions! ➡️ bit.ly/46loPfs
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Philipp Leippe retweeted
Porty is still an orphan #transporter and he wants to find his #substrate! Let's all help Porty by joining the "Unlocking Transporters for Drugs Discovery" #conference in Vienna.📽️
#scicomm #ScienceTwitter #metabolism @IHIEurope
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21 Jun 2023
If you want to hear more about iAspSnFR (and exciting applications), join us for RESOLUTE's glorious closing conference in Vienna (27-29 September) @RESOLUTE_IMI re-solute.eu/conference
5 May 2023
🎉 Thrilled to share 4 yrs of hard work: iAspSnFR preprint at tinyurl.com/38ve4vh9 🔬 GFP-based aspartate sensor, engineered via deep mutational scanning, tested in HEK293 cells. Highly specific for intracellular aspartate! #iAspSnFR #biosensor #aspartate
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Philipp Leippe retweeted
20 Jun 2023
Ever wanted to know what it feels like to be a membrane transporter and be responsible for gatekeeping nutrients and metabolites essential for all biological functions ? JOIN US IN VIENNA for the transporter conference Sept 27-29
re-solute.eu/conference
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