Prince Lab @UChicago. Vertebrate #development with a focus on zebrafish: patterning and migration of neurons, neural crest and placodes education and outreach

Joined December 2020
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The Prince lab stands up for science!
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The Prince Lab retweeted
Had such a great time working with the best undergrad this summer! So proud of Rachel’s impressive new HCR skills (below)! Sad she’s going back to class/can’t be in lab full time this fall, but am very lucky she’s going to continue working with me on our pronephric adventures 🐟
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Adult zebrafish cranial nerves, courtesy of Prince lab wondergrad Theresa Christiansen. #biologyisbeautiful
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Congratulations Noel and Marco! Onward and upward :)
Phenomenal honors thesis on lateral lines and neural crest by @PrinceLab_UofC wondergrad Noel and amazing work on shark lateral lines by Coates lab wondergrad Marco! An honor to have worked with these two. Go #teamlateralline
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Fantastic talks by Prince lab wondergrads Noel McGrory and Theresa Christiansen on the development and innervation of #zebrafish lateral lines!
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And thank you @MadS100tist and @LabPiotrowski for getting us started with these gorgeous fish in the first place!
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Congratulations to Prince Lab postdoc @parahsaramore on her latest publication looking at how Vangl works in the pulmonary mesenchyme to form lung sacculi! Another great reminder that development is beautiful :)
So pleased to announce that the first chunk of my graduate work is out now in @Dev_Cell 🫁🐭🔬 here we investigated the role of the planar cell polarity complex in lung sacculation, identifying a PCP-independent role for Vangl in the pulmonary mesenchyme authors.elsevier.com/c/1isRC…
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Neighbour/partner lab (the Coates lab) wondergrad Marco Lopez from #teamlateralline talking about his amazing work on #shark lateral lines and eco morphology at #SICB2024
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Next Prince lab wondergrad Noel McGrory talked about his fascinating findings on the relationships between #zebrafish neural crest and cranial placodes at #SICB2024
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Prince lab debuts at #SICB2024 with wondergrad Theresa Christiansen talking about her amazing work on lateral line innervation and development- at her first ever conference presentation!
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Neural crest, placodes, sharks and cephalopods- Prince and Coates labs wrapping up an incredible #sicb2024!
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New folks, new updates, same old Chicago fall and same old #zebrafish!
Sharing updates to our lab website voices.uchicago.edu/princela… @PrinceLab_UofC
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The Prince Lab retweeted
I'm excited to announce that @InSDB_79 will be the official guest society of @SocDevBio at the 2023 SDB meeting. Don't forget abstract submission closes April 10th sdbonline.org/2023mtg.
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And it’s a wrap! @UChicago and @MBLScience’s first Mini embryology course, led by our very own @Lab_VPrince and Nipam Patel finished its two week debut today. Here’s to our amazing instructors and all flies, butterflies, zebrafish, squids, chicks and anemones!
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Hot off the press- new work led by our latest graduate Manny Rocha, looking at how trunk neural crest migration is regulated! 1/n
I am thrilled to see the thesis work of recent Prince Lab graduate Manny Rocha out in Developmental Biology authors.elsevier.com/a/1dcF%…
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6/n the environment matters, but only sometimes, it seems. Elegant cell transplantation studies showed that Cdx4 activity was not required in the somitic mesoderm for proper crest migration
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n/n in summary, this work shows that in #zebrafish (like other vertebrates) the head is not like the trunk, and it’s specification and migration are controlled by distinct genes- like cdx4!
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5/n: confocal microscopy reminded us that development is beautiful, but also revealed that Cdx4 deficient zebrafish show aberrant trunk crest migration. Specifically, the ‘leader’ cells lose their identities (politics much?):