Joined November 2022
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🔬🧠 Our paper revealing how loss of neuronal SFPQ impacts the axonal transcriptome and it’s relavence to ALS is out now in @NatureComms A huge thank you to all who contributed and provided help/support along the way 😀 @HouartLab nature.com/articles/s41467-0…

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Richard Taylor retweeted
Extremely excited to share the first preprint from the lab, led by postdoc @RhysLivingstone biorxiv.org/content/10.64898… What did he find? 1/7

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We're recruiting! 🧠 📢 2 roles for an ARUK-funded project exploring mRNA regulation in neurites in neurodegeneration, using zebrafish & human cell models. 🔬Post-doc: kcl.ac.uk/jobs/145646-resear… 🔬Research Assistant: kcl.ac.uk/jobs/145605-resear… Questions? Contact me or @CorinneHouart.

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Professor Corinne Houart and Dr Richard Taylor (part of @UKDRI at King's) received a new £500k grant from @AlzResearchUK to study how RNA-binding proteins, which are disrupted in #dementia, might be important for protecting against degeneration.
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Richard Taylor retweeted
🚨Meet the latest early career researchers awarded Race Against Dementia Fellowships🚨 These rising stars are challenging old ideas and driving bold new approaches to speed up progress @RNA_Richard @SorayaMeftah @Neurowland
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Our review discussing the diversity of RNA types that localise to different parts of the neuronal periphery and the local regulation they undergo has just been published! 😃😃 @nikolas_neuro frontiersin.org/articles/10.…
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Richard Taylor retweeted
Our new findings 👀 Combining zebrafish and human iPSC models of FOXG1 Syndrome we uncover a role for FOXG1 in the cytoplasm, where it controls mitochondrial translation, integrating cell fate decisions and regulation of metabolic activity. @CorinneHouart @HouartLab
A cleaved cytosolic FOXG1 promotes excitatory neurogenesis by modulation of mitochondrial translation - a new therapeutic target for ... biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Our protocol for performing primary culture of zebrafish neurons has been published. It includes details on using transwell inserts, allowing for the isolation of neurites 😃 @CorinneHouart @HouartLab link.springer.com/protocol/1…

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Richard Taylor retweeted
Prematurely terminated intron-retaining mRNAs invade axons in SFPQ null-driven neurodegeneration and are a hallmark of ALS nature.com/articles/s41467-0…

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Richard Taylor retweeted
24 Nov 2022
Celebrating @RNA_Richard’s new paper! Cheers🤩🥂@CorinneHouart
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Mug shot for the wall at work 🧠🔬
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Richard Taylor retweeted
Interesting new hypothesis for motor degeneration in ALS "These new findings not only challenge the dogma that prematurely terminated mRNAs are targeted for degradation but offer novel insights into the mechanisms underlying ALS and possibly other neurodegenerative conditions."
New publication from @RNA_Richard @FurshamH @EMakeyev @HouartLab in @NatureComms ->> Novel ALS hallmark may trigger motor degeneration go.nature.com/3gsjjU0
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Richard Taylor retweeted
Congratulations @RNA_Richard & @FurshamH. Excellent work.
New publication from @RNA_Richard @FurshamH @EMakeyev @HouartLab in @NatureComms ->> Novel ALS hallmark may trigger motor degeneration go.nature.com/3gsjjU0
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Richard Taylor retweeted
🔬🧠 Our paper revealing how loss of neuronal SFPQ impacts the axonal transcriptome and it’s relavence to ALS is out now in @NatureComms A huge thank you to all who contributed and provided help/support along the way 😀 @HouartLab nature.com/articles/s41467-0…

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Richard Taylor retweeted
Honoured to be a part of this amazing study. Congrats @RNA_Richard!
🔬🧠 Our paper revealing how loss of neuronal SFPQ impacts the axonal transcriptome and it’s relavence to ALS is out now in @NatureComms A huge thank you to all who contributed and provided help/support along the way 😀 @HouartLab nature.com/articles/s41467-0…
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New research reveals a new hallmark for #ALS, shedding light on a likely trigger of neurodegeneration. Researchers found that loss of the RNA processing protein, SFPQ, in motor neurons results in their ‘dying back’ . Read more below. #IoPPNNews buff.ly/3EtrIyu
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Richard Taylor retweeted
New publication from @RNA_Richard @FurshamH @EMakeyev @HouartLab in @NatureComms ->> Novel ALS hallmark may trigger motor degeneration go.nature.com/3gsjjU0
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Richard Taylor retweeted
Regulatory mechanism of axonal intron-retaining transcripts relevant to neuro-degeneration and #ALS, led by outstanding @RNA_Richard in @HouartLab General summary: devneuro.org/cdn/news.php?ne…

New publication from @RNA_Richard @FurshamH @EMakeyev @HouartLab in @NatureComms ->> Novel ALS hallmark may trigger motor degeneration go.nature.com/3gsjjU0
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