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Raphaël Tripier & MAC Research Group @RTripier

Professor @UBO_UnivBrest. Organic and Bio-Inorganic Chemistry for Health: Diagnostic and Therapy. Head of the MAC group @UMR_6521. Teaching: PASS & L2toM2Chem

Joined January 2014
  • Tweets 471
  • Following 359
  • Followers 1,020
170 Photos and videos
Ce moment où tu comprends chaque année l'estime que tu as pour tes étudiants... #travaildedingue #concoursdeouf #respectpaces 👍👏😍
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🚨 New paper from the MAC Group (UMR CNRS-UBO 6521 CEMCA)! @TTroadecChem research! Charline Sire’s PhD (ANR JCJC #SMARTFLUOR) reports the first BF₃-appended cyclen complexes as ultrafast ¹⁹F MRI probes 🧪✨ 👉 doi.org/10.1039/d5dt01834j @UBO_UnivBrest @CNRSchimie @DaltonTrans
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What’s better to start the academic year? 🎉📚 Heteropolynuclear Ln complexes for cooperative upconversion in water Congrats to Léna (ex-Brest → PhD IPHC) & Richard (ex-postdoc Brest) — great collab with L. Charbonnière under ANR LUCAS! @jacs_papers 🔗 pubs.acs.org/doi/10.1021/jac…

Heteropolynuclear Lanthanide(III) Complexes for Cooperative Sensitization Upconversion in Water

We report the synthesis of a tritopic ligand, L2, composed of two strongly binding lanthanide (Ln) sites using tris-functionalized triazacyclononane (tacn) scaffolds bridged by a weaker Ln binding...

pubs.acs.org
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🚨 Our latest in Food Chemistry 🍺 Beer meets science! 👉 doi.org/10.1016/j.foodchem.2… Collab : J.-A. Barrat&D. Ben Salem. We show that MRI GBCAs leave gadolinium traces in beers & drinks — highlighting the need to recover & recycle gadolinium & GBCAs! Congrats to Aéla (1st paper)!
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🚨 New paper alert! 🚨 Even in summer, MAC Group keeps it hot! ☀️ Mn(II), Cu(II) & Zn(II) complexes from H₃nota derivatives → structure, stability, MRI relaxivity, 💧 exchange via #17O NMR & DFT. pubs.acs.org/doi/10.1021/acs… @CNRSchimie @UBO_UnivBrest

Mn(II), Cu(II), and Zn(II) Complexes Based on H3nota Derivatives Possessing Picolyl and Picolinate...

Two derivatives of tacn (1,4,7-triazacyclononane) are investigated for their complexation with Cu(II), Zn(II), and Mn(II). The different denticities of macrocyclic ligands Hnoapy and H2noapa offer...

pubs.acs.org
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Raphaël Tripier & MAC Research Group retweeted
Ken Lo@bhkenlo
2 Jul 2025
Photophysical Properties Exploring and Sensitivity to Oxygen in Anisolyl-Picolinate Antenna Conjugated to Azamacrocycles pubs.acs.org/doi/10.1021/acs… @RTripier , Sénèque, Maury, & co-workers @InorgChem #anisolylpicolinate #terbium #gadolinium #europium #O2 #ratiometric #azamacrocycles
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🔬 New paper out! @InorgChem — Development of TE1PA-trastuzumab bioconjugates for 64Cu/67Cu-based imaging and therapy of HER2-positive gastric cancer. Promising preclinical results in a murine model! 🚀 @UBO_UnivBrest @UMR_6521 @COSM @CNRSchimie 👉 pubs.acs.org/doi/10.1021/acs…

Advanced 64Cu/67Cu-Based Theranostics: Application of the Copper Chelator TE1PA to a Murine Model...

The development of 64Cu/67Cu-based theranostic probes addresses the need for integrated cancer diagnosis and therapy. To target HER2-positive gastric cancer, trastuzumab was conjugated to p-SCN-Bn-...

pubs.acs.org
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Our expertise in macrocyclic & lanthanide chemistry shines in this exciting collab with @SynpaTeam on upconversion luminescence. In open access: our new paper in @angew_chem. Congrats to Nadege & Lena #BZH for this great work @UBO_UnivBrest @CNRSchimie @UMR_6521 @AgenceRecherche
Angewandte Chemie@angew_chem
5 Dec 2024
Upconversion Luminescence with Bis-pyclen Yb(III) Chelates: Crown vs. Linear Polyether Linkers in Discrete Heteropolynuclear Architectures (Raphaël Tripier and co-workers) @RTripier @SynpaTeam #openaccess 🔓 onlinelibrary.wiley.com/doi/…
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New paper from the group @ChemicalScience ! An azamacrocyclic chelator enabling 18F PET/19F MRI. Nice work led by @TTroadecChem, managed by #CharlineSire during her PhD @CNRSchimie @UBO_UnivBrest @UMR_6521 collab with @UniAvogadro (L. Tei) #CyclotronRéunionOcéanIndien (E. Jestin)
Chemical Science@ChemicalScience
20 Aug 2024
This new research published in #ChemSci from @TTroadecChem details an azamacrocyclic chelator which enables 18F PET and 19F MRI! Read for free with Diamond Open Access: doi.org/10.1039/D4SC02871F
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Our group was present at the @Iccc2024 in Fort Collins with two invited or selected presentations! Very happy to took part of this great conference! @UBO_UnivBrest @UMR_6521 @CNRSchimie
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Raphaël Tripier & MAC Research Group retweeted
Rafael Gramage-Doria@Rafa_gramage
25 Jul 2024
Check out this PhD position to start before the end of 2024 @reseauSCF @RSEQUIMICA @Chemjobber DM for details/queries @CNRS @CNRSchimie @chimie_ISCR @RoySocChem @AmerChemSociety @EuChemS thanks for sharing!
Thibault Troadec@TTroadecChem
24 Jul 2024
PhD Position available! With @Rafa_gramage , we are looking for a motivated PhD candidate on an exciting project related to synthesis, coordination chemistry and catalysis with supramolecular assemblies. Check the details here : bit.ly/3WzGTjH and contact us!
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A nice concert for my birthday!
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J Org Chem/Org Lett@JOC_OL
12 Apr 2024
New Applications of Copper(I)-Catalyzed Alkyne–Azide Cycloaddition in Developing Versatile Cyclam-Based Chelating Agents of Interest. New in #JOrgChem from Le Bris, Tripier @RTripier, and colleagues pubs.acs.org/doi/10.1021/acs… @UBO_UnivBrest @CNRSchimie @UMR_6521
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Our new paper in @JOC_OL is now online as ASAP article! Interested in click-chemistry to extend the scope of the C-functionalization of cyclam to have bifunctional chelates of interest? pubs.acs.org/doi/10.1021/acs… Congratulations #CedricOllier!!! @UBO_UnivBrest @CNRSchimie @UMR_6521

Extending the Scope of the C-Functionalization of Cyclam via Copper(I)-Catalyzed Alkyne–Azide...

Cyclam, known for its potent chelation properties, is explored for diverse applications through selective N-functionalization, offering versatile ligands for catalysis, medical research, and materi...

pubs.acs.org
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New collaboration and new paper from the group!! Trehalose-polyamine/DNA nanocomplexes thanks to C-functionalized cyclams: cell and organ transfection selectivity - in Journal of Materials Chemistry B pubs.rsc.org/en/content/arti… @CNRSchimie @UMR_6521 @UBO_UnivBrest

Trehalose-polyamine/DNA nanocomplexes: impact of vector architecture on cell and organ transfection...

A novel family of precision-engineered gene vectors with well-defined structures built on trehalose and trehalose-based macrocycles (cyclotrehalans) comprising linear or cyclic polyamine heads have...

pubs.rsc.org
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A very nice work and paper from the group thanks to @Marie_lroy_ and @TTroadecChem and a new collaboration ! C-bifunctionalized bis-macrocycles for CXCR4 inhibition. @UBO_UnivBrest @CNRSchimie @UMR_6521
Thibault Troadec@TTroadecChem
28 Mar 2024
Great work on a new C,C'-bis-cyclam for CXCR4 inhibition is now online at @OrgBiomolChem, with very cool synthetic methodology developed by @Marie_lroy_ and a nice collaboration with D. Schols lab in KU Leuven for the biology! bit.ly/OBCLeRoy
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New publication from the group in @InorgChem. Some new pyclen derivatives for metal coordination… @UBO_UnivBrest @CNRSchimie @UMR_6521 Nice collaboration with @CarlosPlatas9 #gyula.tircso @GuerbetGroup
Inorganic Chemistry@InorgChem
14 Feb 2024
Nizou et al. report the preparation of mono-N-functionalized pyclens and their side-bridged analogues, noting the increased stiffness and basicity of pyclen when an ethylene bridge is introduced. Don’t miss our #TOCoftheWeek: pubs.acs.org/doi/10.1021/acs…
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Few days invited to Upsalla University… Many thanks to #EszterBorbas for her kindness and congratulations for her exceptional work!
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CEM Corporation
@CEMcorporation
28 Nov 2023
Congratulations to Prof. Raphael Tripier and his @UBO_UnivBrest team on their new Discover 2.0 Microwave Synthesizer! From medical imaging to radioimmunotherapy, the possibilities are endless. All the best on your innovative research journey! #Research #Innovation
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Raphaël Tripier & MAC Research Group retweeted
Inorganic Chemistry@InorgChem
8 Nov 2023
New monomeric and polymeric lanthanide species generated by tacn- or pyclen-based chelators with pyridinylphosphonic pendants. From @SynpaTeam and @RTripier. Learn all about it: pubs.acs.org/doi/10.1021/acs…
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Raphaël Tripier & MAC Research Group retweeted
UBO - Univ. Brest@UBO_UnivBrest
16 Oct 2023
Pas une goutte à perdre 💧 avec la chaire « MeGadoRe » pour Medical Gadolinium Recycling qui vise à réduire l'impact environnemental des produits de contraste en #IRM #ImagerieMedicale #DeveloppementDurable @GuerbetFrance @RTripier @cmarkea @lemarlab @UMR_6521 @guerbet
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