Clinician and scientist focusing on multiple myeloma. Chair, GMMG study group. Tweets are my own. @HDMyeloma @ukhd @dkfz
Joined April 2023
- Tweets 185
- Following 97
- Followers 440
- Likes 243
22 Photos and videos
Marc S. Raab retweeted
Clinical Scores to Predict Toxicities and Outcomes in Patients with Multiple Myeloma Undergoing Bispecific T-cell Engager Therapy
@BCD_AACR
aacrjournals.org/bloodcancer…
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Marc S. Raab retweeted
Now online: Clinical Scores to Predict Toxicities and Outcomes in Patients with Multiple Myeloma Undergoing Bispecific T-cell Engager Therapy doi.org/10.1158/2643-3230.BC…
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Marc S. Raab retweeted
Fascinating - albeit a little terrifying - @LeukemiaJnl work by 🇩🇪
How does GPRC5D loss affect surviving myeloma #MMsm clones? Here, remaining cells appear to be more aggressive.
Will be important to validate / rebut as talquetamab moves into earlier lines... hopefully soon!
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Marc S. Raab retweeted
Apr 3
In this week's issue of @BloodPortfolio, our study of global access to CAR T, led by Alex Ge.
Thanks to Blood editors for making it a plenary paper!
Free access link: authors.elsevier.com/a/1mt5a…
Thanks @kjmeetswrld for the thoughtful commentary
ashpublications.org/blood/ar…
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Marc S. Raab retweeted
5/5 Dr Marc Raab On exciting data from trispecifics and NK engagers
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Marc S. Raab retweeted
Mar 27
Insightful algorithm for risk-informed management of newly diagnosed #MultipleMyeloma in the era of Quads upfront by @MyMKaiser @ESHaematology
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Marc S. Raab retweeted
Day 2 of #ESHMM26 6th session on personalising treatment in myeloma
Focusing on high-risk disease, CAR-T and bispecific toxicities, MRD-directed strategies, & precision medicine
@MyMKaiser @NicoGagelmann @End_myeloma Dr Marc Raab
#ESHCONFERENCES
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Marc S. Raab retweeted
Mar 28
Provocative presentation by Dr. Mirco Friedrich @mircoscopy at @Myeloma_Society 7th Immune Effector on whether or not T-cell exhaustion exists in #myeloma #mmsm @NikhilMunshiMD @szusmani @NBahlis
Mar 28
Big discussion this morning at @Myeloma_Society 7th Immune Effector Workshop on the “T-cell Mechanism That Shall Not Be Named” @szusmani @myelomaMD @NikhilMunshiMD @IrenemGhobrial @NBahlis #mmsm
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Marc S. Raab retweeted
Mar 24
Other info:
No beneflt from salvage HCT (if one was given in 1st response) vs continous Rd treatment (IMO)
Careful about offering HCT at relapse (not given purposely in first response but "saved" for later stages) since attrition in MM up to 30%
Remember best option 1st #EBMT26
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Marc S. Raab retweeted
Mar 24
#EBMT26 Plenary Session on Multiple Myeloma
Thats the slide
Hopefully in the future we may stop offering HCT to patients
It is very hard to endure for most patients
Not yet though
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Marc S. Raab retweeted
Now online: Reading the “T” Leaves: Predicting Outcomes with Bispecific Antibodies in Multiple Myeloma doi.org/10.1158/2643-3230.BC…
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Mar 13
Wrapping up the MMBridge meeting in Milan (brilliantly organized by Niccolò Bolli and Matteo Da Via)
@MyMKaiser @RascheLeo, Jan Kroenke
#mmsm
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Marc S. Raab retweeted
Now online: Clinical scores to predict toxicities and outcomes in patients with multiple myeloma undergoing bispecific T-cell engager therapy doi.org/10.1158/2643-3230.BC…
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Marc S. Raab retweeted
#Myeloma Paper of the Day: Patients w/ CAR-HEMATOTOX ≥3 or Endothelial Activation & Stress Index >median have increased risk prolonged hospitalization, antibiotic tx & fever during step-up dosing cytopenias, severe infections, inferior outcomes: pubmed.ncbi.nlm.nih.gov/4168…. #mmsm
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Marc S. Raab retweeted
#MMsm picture worth >1000 words:
1️⃣ Low-grade infections can persist, esp with BCMA bsAbs
2️⃣ Imp to report infection-months, not just "Yes/no ≥1 Gr3 infxn"
3️⃣ Look at all that IVIG / IgRT usage 👏 Love it!! But of course still not panacea.
Great work #mersi @RascheLeo et al!
#Myeloma Paper of the Day: T-cell-engaging therapies for myeloma are linked to a high burden of prolonged, low-grade infectious complications, especially with bispecific therapy and particularly after BCMA-directed treatment: pubmed.ncbi.nlm.nih.gov/4161…. #mmsm
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Jan 15
Amazing job @hollyleeYJ !!
Jan 15
Delighted to share a MonumenTal work led by Dr Holly Lee @hollyleeYJ and many collaborations detailing the multimodal resistance mechanisms to anti-GPRC5D TCE in multiple myeloma out today in @NatureMedicine nature.com/articles/s41591-0… @UCalgaryMed @Charb_Cancer #msmm (1/12)
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Marc S. Raab retweeted
Jan 15
Grateful for the amazing collaboration with @RaabMarc, @RascheLeo, H Einsele, N Weinhold, M Truger, M Kortum, C Riedhammer, JH Frenking, J Canton, D Vishwamitra, S Skerget, Y Cho, E Kastritis, L Boise, J Eckmann, J Somandin, @FrancescoMaura4, J Corre, H Avet-Loiseau & P Neri
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