Read our Spotlight article: One for All and All for One: New Insights into Enhancers Driving MYC Dysregulation aacrjournals.org/bloodcancer… Its a commentary on the very nice paper by Iyer and colleagues!

Second preprint now on biorxiv!! 🧵⬇️ thanks to all our co authors @MarijeHavermans @RogerMulet @SmeenkLeonie and others i cant find on here ! Also on bluesky 🦋: bsky.app/profile/dpastoors.b… @erasmusmcblood

EHA Research Conference in Malaga In March 2025: "Transcriptional control and chromatin alterations in normal and malignant hematopoiesis" Fantastic opportunity for junior investigators to present and discuss their work with young and experienced scientists. Great program!

Congratulations to this year’s CBTH Scholars! Throughout the program, scholars explored a range of topics and were guided by mentors to elevate their projects to new heights. In addition to advancing their own research, they delved deeper into these key areas: 👉 Bayesian Statistics ️👉 Science Communication  👉 Multi-Layered Data Integration 👉 Data Visualization 👉 Proteomics 👉 Epigenetics Would you like to join our next cohort? This free program will open for applications in June 2025! Don’t miss out on this amazing opportunity to elevate your skills in Computational Biology.

07 October 2024 at 16.00 CET Erasmus Hematology Virtual Lecture. We have: Kellie Machlus, Boston Children’s , with "Unraveling roles for megakaryocytes beyond platelet production through novel model systems" Spread the news! us06web.zoom.us/j/8272215941… @theclotthickens

Don't miss it! Erasmus Hematology Virtual lecture 23 September at 16.00 CET with: Alexander Bick, Vander Bilt University, Nashville. Title: "Clonal hematopoiesis: causes, consequences and management" Link: us06web.zoom.us/j/8272215941…

Erasmus Virtual Hematology Lectures starts again on Monday September 2 at 16.00 CET! We have MAXIM PIMKIN from Harvard/Boston with: "Gene-regulatory networks in leukemia maintenance and immune escape". Link: us06web.zoom.us/j/8272215941… Spread the news! @pimkin

New paper in Cell Reports: STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia doi.org/10.1016/j.celrep.202… Another Regensburg/Rotterdam collaboration! @ClaudiaGebhard @RogerMulet Fischer/Rehli

Proud of the review by Roger Mulet-Lazaro on "Oncogenic Enhancers in Leukemia" in Blood Cancer Discovery in August issue. Great stuff for teaching! aacrjournals.org/bloodcancer… @RogerMulet @BCD_AACR

The Erasmus Hematology Virtual Lecture Series starts again September 2, with a fantastic line up: @pimkin,@AlexBickMDPhD, @theclotthickens, @jonasschluter, @job_dekker, @NBahlis, @Elsa2Bernard Retweet and share with your colleagues and friends us06web.zoom.us/j/8272215941…

New paper in NatureComm: "Epigenetic alterations affecting hematopoietic regulatory networks as drivers of mixed myeloid/lymphoid leukemia". nature.com/articles/s41467-0… Great Rotterdam/Regensburg collaboration: @RogerMulet @ClaudiaGebhard Bas Wouters @DelwelRuud Michael Rehli

Extremely grateful for receiving the EHA advanced research grant! Looking forward delving deeper into the disease mechanisms underlying AML. Congratulations to all EHA award winners! #EHA2024 @EHA_Hematology @ErasmusMC @erasmusmcblood

A big thank you to everyone involved in this week's joint @EBItraining and @EHA_Hematology computational biology training in hematology (CBTH) course. 2025 applications are now open if you want to be in the next cohort of early-career researchers: ehaweb.org/research/research…

The previous tweet was my first ever. 🤓🕺 We had another nice study in Blood, published in July. Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML | Blood | American Society of Hematology ashpublications.org/blood/ar…

We generated t(3;8) MYC super-enhancer/EVI1-eGFP translocations in human cells. The importance of CTCF-facilitated loops in enhancer hijacking is demonstrated. nature.com/articles/s41467-0…

Truly becoming the epidemic of the unvaccinated. So sad that so many people have been fooled by shamans and snake oil salesman