Researcher, Erasmus MC Cancer Institute, Rotterdam, the Netherlands. Visiting post-doc Sanger Institute, Cambridge, UK.
Joined August 2017
- Tweets 450
- Following 461
- Followers 550
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33 Photos and videos
Pinned Tweet
16 Jun 2024
Extremely grateful for receiving the EHA advanced research grant!
Looking forward delving deeper into the disease mechanisms underlying AML.
Congratulations to all EHA award winners!
#EHA2024 @EHA_Hematology @ErasmusMC @erasmusmcblood
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Interested in the construction of high performance computing clusters? Do you have affinity with scientific computing and AI research?
The Erasmus MC is looking for a Senior Engineer to help build its state-of-the-art HPC cluster.
@ErasmusMC #HPC #IT
werkenbijerasmusmc.nl/en/vac…
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Mathijs Sanders retweeted
3 Jul 2025
Delighted to share our latest on longitudinal methylation dynamics preceding cancer. Epigenetic signs of AML appear in blood DECADES before Dx. By brilliant @__AFonseca
✅Early cancer
✅Methylation drivers
✅Epimutation rates
✅CpG lineage tracing
biorxiv.org/content/10.1101/…
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Mathijs Sanders retweeted
28 Apr 2025
Read the commentary: Putting AML Differentiation States on the BoneMarrowMap, by Jonas Berger and Livius Penter, online now concurrent with #AACR25. doi.org/10.1158/2643-3230.BC…
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longcallD is a new variant caller for genomic long reads. It jointly calls phased small and structural variants. Single binary, one command line for the whole process. Comparable accuracy to mainstream callers. Great work by Yan Gao. github.com/yangao07/longcall…
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Mathijs Sanders retweeted
20 Mar 2025
The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our Nature paper:
nature.com/articles/s41586-0…
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Mathijs Sanders retweeted
15 Mar 2025
Applications for #TRTH2026 are now open!
Are you an early-career researcher in translational hematology? The EHA-ASH TRTH program provides a unique opportunity to enhance your research skills with guidance from leading international experts.
🔹 Applications open today, March 15!
🔹 Deadline: June 26, 2025, at 11:59 PM ET
Don’t miss this chance to advance your career in hematology research. Apply now!
Learn more: eha.fyi/ashehaTRTH
Apply now: eha.fyi/registerTRTH
#HematologyResearch #CareerDevelopment #TRTH #TRTH2026
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Mathijs Sanders retweeted
2 Oct 2024
07 October 2024 at 16.00 CET
Erasmus Hematology Virtual Lecture.
We have:
Kellie Machlus, Boston Children’s , with
"Unraveling roles for megakaryocytes beyond platelet production through novel model systems"
Spread the news!
us06web.zoom.us/j/8272215941…
@theclotthickens
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23 Sep 2024
Today, we have Alexander Bick presenting! Don't miss it.
23 September at 16.00 CET
Title: "Clonal hematopoiesis: causes, consequences and management"
Link: us06web.zoom.us/j/8272215941…
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Mathijs Sanders retweeted
4 Sep 2024
Excited to share our latest study in @JCO_ASCO on improving risk stratification for older patients (≥60 yrs) with Acute Myeloid Leukemia (AML)!
We developed a novel prognostic model: AML60 . #Leukemia #AML link: ascopubs.org/doi/full/10.120…
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Mathijs Sanders retweeted
6 Sep 2024
Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/scie…
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30 Aug 2024
New review by @sjfhermans, @niek_maas, @JurjenVersluis and others, detailing how real-world data can be of added value if collected and used appropriately!
30 Aug 2024
New paper out in @JAMAOnc! 🚨
Real-world data (RWD) external control arms are gaining traction in prospective studies, but we need to balance their advantages with meeting evidentiary standards
Our review highlights significant differences between RWD and trial data🧵(1/7)
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Mathijs Sanders retweeted
23 Aug 2024
🚨 Excited to share our latest paper in @CellCellPress identifying how under-replicated chromosomes in micronuclei become shattered by the Fanconi anemia pathway during mitosis. This work was led by @UTSWGradSchool student @JustinEngel17. 🧵 (1/13):
cell.com/cell/fulltext/S0092…
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Mathijs Sanders retweeted
17 Aug 2024
Join us! The Machado Lab at @Cambridge_Uni is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/
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Mathijs Sanders retweeted
15 Aug 2024
Interested in non-coding alterations, large-scale genomics, leukemia? Collaboration between @CMullighan and Teachey labs.
Genomic analysis of >1300 WGS/WTS/WES samples from T-lineage acute lymphoblastic leukemia, out now in @Nature
nature.com/articles/s41586-0…
Highlights (7):
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Mathijs Sanders retweeted
7 Aug 2024
Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]
7 Aug 2024
Academic co-founder, Peter Campbell, Ph.D., is joining the Quotient team as CSO. We look forward to advancing the first ever #SomaticGenomics platform under his leadership. Read more: bit.ly/3YBCkqS
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Mathijs Sanders retweeted
5 Aug 2024
Proud of the review by Roger Mulet-Lazaro on "Oncogenic Enhancers in Leukemia" in Blood Cancer Discovery in August issue. Great stuff for teaching!
aacrjournals.org/bloodcancer…
@RogerMulet @BCD_AACR
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PhD candidate to study the bone marrow microenvironment in leukemia @MathijsSanders
Using cutting-edge technology, you will investigate the cell-intrinsic and cell-extrinsic drivers of AML.
jobrxiv.org/job/erasmus-medi…
#single_cell_biology #spatial_multio...
jobrxiv.org/job/erasmus-medi…
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11 Jul 2024
A fully funded PhD Position available in the Sanders lab focusing on single cell transcriptomics and spatial multiomics in #leukemia!
Interested in novel technologies centered on single cell biology! Please apply!
werkenbijerasmusmc.nl/en/vac…
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10 Jul 2024
Happy to report that we have received the Erasmus MC2 Research Innovation Grant! @MassaarSanne and the team will investigate the driver mechanisms behind disease progression in myeloid neoplasms.
#MDS #AML #ErasmusMC #EMC
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9 Jul 2024
Extremely grateful for receiving the LSBR Fellowship! In this project we are investigating the drivers of acute myeloid leukemia with myelodysplastic related changes.
@ErasmusMC @erasmusmcblood #LSBR
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