Exploring nucleic acid-protein interactions at a higher resolution. Based @ImperialMed and @MRC_LMS. Opinions are my own.
Joined June 2014
- Tweets 529
- Following 841
- Followers 1,894
- Likes 1,343
72 Photos and videos
Pinned Tweet
27 Jul 2023
Winter is coming... Fancy some single-molecule science combined with winter sports?
Send your abstracts for the 3rd SMB Les Houches 2024 at
smbleshouches.com
Abstract selections will begin on 2nd Oct. 2023
@NynkeDekkerLab
@LUMICKS_nl
@PI_Physik_Inst
@MadCityLabs1
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David Rueda retweeted
3 Nov 2023
🚨We are hiring🚨 We are looking for a chemist to join our team and synthesise novel functional ligands to interrogate chromatin dynamics! Please apply following the link below👇 DM or email me if you want more info. RT appreciated.
imperial.ac.uk/jobs/descript…
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David Rueda retweeted
25 Oct 2023
As you know, these are difficult days in Israel, but the Scientific work has to continue. What started as an open discussion over Twitter/X has matured into a review of
#PIFE
doi.org/10.1088/2050-6120/ac…
Enjoy the read
17 Oct 2021
Nice implementation of UIFE (originally PIFE). Should we start referring to it as photo-isomerization induced fluorescence enhancement (PIFE) in general?
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David Rueda retweeted
31 Oct 2023
How can we discover better neuroactive compounds?
A 4-year fully funded PhD position in my lab in London to work on one of our most interesting projects. In collaboration with @aexbrown
Apply by 12 December, start in Oct 2024.
findaphd.com/phds/project/ho…
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David Rueda retweeted
2 Nov 2023
Excited to accept a position start my group @sheffielduni in @MCB_Sheffield. Huge thanks to the support from @BoultonLab, part of my lab will work closely with them using single-molecule techniques to understand telomeres. If you’re interested in working with us get in touch!
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David Rueda retweeted
16 Oct 2023
How does the structure of target DNA affect CRISPR/Cas9 off-target activity during gene editing? We show that negative DNA supercoiling dramatically reduces Cas9 specificity. Find out more here: doi.org/10.1016/j.molcel.202…
@MolecularCell @LUMICKS_nl @MRC_LMS @TheCrick @ucl
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David Rueda retweeted
11 Oct 2023
📢 We're now the MRC Laboratory of Medical Sciences! Going UK-wide, beyond just London. Proudly in sync with our siblings LMB, Cambridge. Check out our new look! #ForAllOfUK #MRCUpdates @MRC_LMB @UKRI_News
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David Rueda retweeted
4 Oct 2023
6 out of 8 @NobelPrize winners in Medicine, Physics, and Chemistry this year are immigrants! 🌍🏆 #DiversityInScience #NobelPrize
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David Rueda retweeted
4 Oct 2023
Names of purported Nobel chemistry prize winners inadvertently released reuters.com/world/names-purp…
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David Rueda retweeted
15 Aug 2023
🚨Final day to apply for this PhD studentship in the Cochemé lab @MRC_LMS @ImperialCollege🚨
#Redox #Ageing #Drosophila
- Position available from October 2023
- Funding for 4 years, open to all applicants (UK and worldwide)
- Deadline: Weds 16th August
findaphd.com/phds/project/re…
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David Rueda retweeted
8 Aug 2023
Come work with us! We are recruiting a 2-yr postdoc/research fellow for an exciting project using single-molecule microscopy to study viral replication. closing date 17th Sept. More info & how to apply here: warwick-careers.tal.net/vx/l…
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David Rueda retweeted
26 Jul 2023
Besides BRCA2 directly binding to RPA-ssDNA, we also observed BRCA2 molecules moving along the dsDNA arms! Some of them were even able to reach the gap edge and nucleate RAD51. We calculated BRCA2 diffusion rates using MSD analysis w/ help from @arthur_pol in @RuedaLab. (6/10)
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David Rueda retweeted
25 Jul 2023
I'm recruiting a Senior Bioinformatician to join the @MRC_LMS Bioinformatics Facility. New building, new HPC system, new start! Know your way around *seq workflows, like Nextflow, love reproducible science ... get in touch! #Bioinformatics #jobs #London
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David Rueda retweeted
14 Jul 2023
nytimes.com/2023/07/13/scien…
The passing of a pioneer.
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David Rueda retweeted
16 Jul 2023
Thanks to Jane Dyson, @LabMaillard, and @RuedaLab, as well as @ckinzthompson and all the other contributing speakers for an AMAZING Proteins in Motion session on Day 3 of #PS37!
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David Rueda retweeted
3 Jul 2023
If everyone who has been grateful for the NHS over the past 75 years followed and retweeted we’d reach a million by midnight.
Please take just two seconds to show you care.
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David Rueda retweeted
1 Jul 2023
Cold Spring Harbor Lab: Where White People Talk About DNA.
1 Jul 2023
Yuck. Cold Spring Harbor Lab meeting "celebrating" 50 years of recombinant DNA is a #manel #YAMMM
With a history of issues in sexism (e.g. Watson) at CSHL this is sad. And bonus featuring Lander w/ his own history of issues as session chair & panel discussion leader
ALT image shows lists of people for this meeting with yellow and green highlighting being used for people inferred to be male or female (from information on their web sites). Shows session chairs 12:1 M:F, Panel Leaders 4:0 M:F and Speakers 47:8 M:F.
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23 Jun 2023
Great science and great fun! Single molecule and DNA Repair, a great combo!
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21 Jun 2023
We are excited to announce the 2023 Next Generation Biophysics Symposium #NGBS2023 in person and virtually at the @MRC_LMB (27 Sept).
Registration is now open here:
mrc-lmb.cam.ac.uk/sites/next…
A great lineup of speakers!
@MRC_LMB @ASTRAZENECAUK @imperialcollege @MRC_LMS
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David Rueda retweeted
19 Jun 2023
This is beautiful.
Making one protein, from one mRNA, takes minutes. This method images single mRNAs as they are translated by ribosomes. And can do it for >1 hour.
Translation is start-stop; not continuous. (mRNAs = red; translation sites = green).
cell.com/molecular-cell/full…
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