@simonsfdn postdoc fellow @BigelowLab @rstepanauskas Lab | @faylward lab alum | I like big phage & I cannot lie, aspiring Wumbologist 🦠🧬🌊🆒
Joined November 2012
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What if we could put all tailed phages in a single, evolutionarily meaningful phylogeny? Check out the latest from the Aylward Lab (twitterless) and myself - we present a phylogenomic framework toward unifying phage diversity! 🧬🤝 biorxiv.org/content/10.1101/…
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Congrats to @chang_tianyi @julesinboots @stepanausk8197 on helping the environmental microbiology community better understand the strengths and weaknesses of SAGs versus MAGs! Using either/both data types? Read this to more accurately interpret your data link.springer.com/article/10…
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Alaina Weinheimer @scubalaina@genomic.social retweeted
14 Mar 2024
How many SAR11 cells are phage-infected in the environment? And what are zombies🧟♂️?
We studied phage infection in SAR11 using the🔬. Up to 19% of SAR11 cells were phage infected and many host cells were devoid of ribosomes🧟♂️!
What else did we find? A 🧵
researchsquare.com/article/r…
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Alaina Weinheimer @scubalaina@genomic.social retweeted
3 Jul 2023
Super cool paper from Ernie Osburn, @Gaowen_Yang @mrillig and @strickm27 showing that alpha-diversity relationships with soil ecosystem function are non-causal.
3 Jul 2023
"We show... microbial community membership and abundance characteristics, rather than α diversity, most strongly predict ecosystem functions and... are more likely to represent the direct microbial drivers of functional changes at the ecosystem scale."
nature.com/articles/s43705-0…
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How tf didn’t the UK or Ukraine or Slovenia or Austria get more points????
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Alaina Weinheimer @scubalaina@genomic.social retweeted
10 Apr 2023
Can large language models understand genomic sequences and uncover new biology? 🧬🧬🧬 Excited to share a new #preprint with @sokrypton, @ancornman1, and @pgirguis. TLDR: A Large Language Model for genomic sequences! #genomics #AI #machinelearning #NLP
biorxiv.org/content/10.1101/… 1/
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Instead of asking “did you feed the cat her wet food?”, we ask “were you the hero today?” And I’m only now realizing how sad it is that we have to exaggerate our importance to her to convince ourselves she needs us bc cats
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Alaina Weinheimer @scubalaina@genomic.social retweeted
6 Apr 2023
New paper alert!🌋🌊🧬🦠 I'm so excited to share our paper "Viruses interact with hosts that span distantly related microbial domains in dense hydrothermal mats" 1/ nature.com/articles/s41564-0…
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I’m sure I’m not the first to ask this, but if Pseudomonas exists, who is the real monas?
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Casually asked my friend “do you know Bob’s Red Mill flour?” , and just realized the full depths of my baking addiction mindset
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Alaina Weinheimer @scubalaina@genomic.social retweeted
16 Mar 2023
Excited to share our new preprint! Phage tRNA act as a counter to the Retron defense system, and Rad is a broad-spectrum retron inhibitor.
biorxiv.org/content/10.1101/…
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Alaina Weinheimer @scubalaina@genomic.social retweeted
8 Mar 2023
In @Nature today (open access), we report the structural and mechanistic basis of how bacteria harvest energy from air. We reveal a novel enzyme, Huc, consumes atmospheric levels of hydrogen gas and transfers the derived electrons for aerobic respiration. nature.com/articles/s41586-0…
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Alaina Weinheimer @scubalaina@genomic.social retweeted
3 Mar 2023
Do you have a crappy phage? Do you have 4 days? We found that we could rapidly evolve our bacteriophages to increase low titers by 100-10,000 times in only four days! In many cases, the host ranges expanded at the same time! Amazing! Try it! #Phage #Evolution @kok_danielle
3 Mar 2023
In Vitro Evolution to Increase the Titers of Difficult Bacteriophages: Rapid Appelmans Protocol biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Alaina Weinheimer @scubalaina@genomic.social retweeted
28 Feb 2023
Still looking for a postdoc in soil viral ecology, start date flexible, bioinformatics/omics background useful but you don't need virology experience, apply by March 6 if possible
6 Feb 2023
Postdoc at UC Davis in soil viral ecology now open for applications. Apply by March 6 if possible, start date flexible. recruit.ucdavis.edu/JPF05497
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Is it acceptable yet to have a cat/pet in your professional headshot? (The only recent pics I have of just me currently without alcohol)
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31 votes • Final results
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Working from home today, but not without close supervision
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Alaina Weinheimer @scubalaina@genomic.social retweeted
16 Feb 2023
Four principles to establish a universal virus taxonomy
journals.plos.org/plosbiolog…
It was a wonderful experience to share a workshop with world experts on virus diversity, genomics and classification.
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Alaina Weinheimer @scubalaina@genomic.social retweeted
18 Feb 2023
Impact of microbial genome completeness on metagenomic functional inference | ISME Communications nature.com/articles/s43705-0…
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