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Chandra Lab @SChandraLab
Joined November 2020
  • Tweets 99
  • Following 62
  • Followers 345
26 Photos and videos
Chandra Lab retweeted
Yale Neuroscience@YaleNeuro
Jun 4
Lipofuscin accumulates in the brain with age and neurodegeneration. But what is it, where does it come from, and where does it go? The @SChandraLab built a lipofuscin brain atlas and shed light on its composition. medicine.yale.edu/news-artic…
Green fluorescing dots of lipofuscin in the brain of a mouse lacking PPT1. Image from the Chandra lab.

ALT Green fluorescing dots of lipofuscin in the brain of a mouse lacking PPT1. Image from the Chandra lab.

Chandra Lab@SChandraLab
May 26
Earlier this month, this exciting paper from previous PhD student in the lab, Sofia, came out! Take a look at her exciting work characterizing lipofuscin in aging and Neuronal Ceroid Lipofuscinosis! link.springer.com/article/10…
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Huge congratulations to Dr. Chandra @leah_harmon13, whose thesis work forms the basis of this Blavatnik funded project!
Yale Neuroscience@YaleNeuro
Mar 24
CONGRATS 🎉 to @YaleNeuro's Sreeganga Chandra (@SChandraLab), @Janghoolim, & Stephen Strittmatter, who recently received funding 💰 from the Blavatnik Family Foundation for their innovative research in the field of #neuroscience! 🧠 More 👇 ventures.yale.edu/news/blava…
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Chandra Lab retweeted
Yale Neuroscience@YaleNeuro
Mar 24
CONGRATS 🎉 to @YaleNeuro's Sreeganga Chandra (@SChandraLab), @Janghoolim, & Stephen Strittmatter, who recently received funding 💰 from the Blavatnik Family Foundation for their innovative research in the field of #neuroscience! 🧠 More 👇 ventures.yale.edu/news/blava…
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Had a wonderful time discussing Parkinson's disease research at the World Parkinson's Congress 2026! PhD candidate @leah_harmon13 presented her work on synuclein and Multiple Systems Atrophy
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Earlier this month, this exciting paper from previous PhD student in the lab, Sofia, came out! Take a look at her exciting work characterizing lipofuscin in aging and Neuronal Ceroid Lipofuscinosis! link.springer.com/article/10…

Lipofuscin accumulation in aging and CLN1 is associated with deficient de-S-acylation, lyso-mitoc...

Acta Neuropathologica - Lipofuscin is an autofluorescent material that accrues in brain tissues with age and in Neuronal Ceroid Lipofuscinosis (NCL), a neurodegenerative disease with pediatric...

link.springer.com
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This work was also recognized by Alzforum! Read more here: alzforum.org/news/research-n…
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Our paper exploring the link between cognitive deficits and GBA mutations in Parkinson's disease is out now in @NatureComms. Congratulations to @VidyadharDJ and all of the authors on the success of their hard work! nature.com/articles/s41467-0…

Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked...

Nature Communications - GBA, a major gene for Parkinson’s disease and dementia with Lewy bodies, is associated with increased risk of developing dementia. Here, we demonstrate that GBA...

nature.com
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See also this great write-up from @YaleMed about this work! medicine.yale.edu/news-artic…
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It was an honor for PhD students @leah_harmon13 @maallnutt to be part of the Connecticut contingent at last week's Parkinson's Policy Forum Hill Day run by @MichaelJFoxOrg @APDAParkinsons to meet with our CT representatives and advocate for funding for Parkinson's research!
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Had a wonderful & engaging meeting at Grand Challenges in Parkinson's disease earlier this month! It was good to see lab alumni Jamie and Mike!
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Postdocs: Apply now for the SYNAPSES seminar series @YaleNeuro @KavliAtYale ! Deadline to apply is September 7th, 2025.
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Thank you to @PFResearchTeam for this story highlighting the work we've been doing at Yale with @PDClab and Dr. Shawn Ferguson's lab as a Parkinson's Foundation Research Center! parkinson.org/blog/research/…

From Parkinson’s Foundation Research Center to Powerhouse: How Yale Became a Leader in Parkinson’s...

parkinson.org
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The lab had a wonderful time visiting the new neuroscience exhibit at the @yalepeabody! Congratulations to curators @aprilnpruitt, @dacolon, and everyone who worked on this exciting exhibit!
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On #RareDiseaseDay2025, we want to recognize patients with Neuronal Ceroid Lipofuscinosis (NCL) and their families. Graduate student Alex Esqueda and recent grad Dr. Sofia Tieze are working to improve our understanding of the pathogenesis of these rare and devastating diseases.
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Excited to be at the organization meeting for the 2026 World Parkinson Congress- save the dates! @WorldPDCongress #WPC2026
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medicine.yale.edu/news-artic… Check out this coverage of our recent publication with @lesleylezhang, @DavidHaflerMD, and colleagues!

Parkinson’s Disease Associated With Neuroinflammation in the Brain, New Analyses Reveal

Using single-cell transcriptomics and proteomics, Yale researchers have created a detailed cell atlas of brains affected by Parkinson’s disease.

medicine.yale.edu
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PhD student in the lab Leah Harmon presenting her work on Dopamine transporter imaging techniques at #SfN24!
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Hey #SfN24 attendees- check out the Celebration of Women in Neuroscience event on 10/8 (hosted by our own Dr. Chandra!) 👩‍🔬🧠
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On this #PostdocAppreciationWeek we're celebrating our 3 incredible postdocs, @VidyadharDJ @ChungJungLi1, and Na Wang! Your experience, advice, and brilliant science are invaluable to our lab!
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We're thrilled to share that Sofia will be defending her thesis in just two short weeks! Come join us on 9/25 to hear about (and celebrate!) all of her incredible thesis work 🎓
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