Lab of Adrian Salic @harvardmed @HarvardCellBio Our lab studies how vertebrate cells send and respond to Hedgehog signals #hedgehog šŸ¦” #cilia

Joined March 2018
32 Photos and videos
13 Jul 2019
Congratulations Hui-Ting!
Our structure of thee BBSome is out: cell.com/structure/fulltext/…. We find evidence of a conformational change upon recruitment to membranes. Fantastic collaboration with Tom Walz, special thanks to Hui-TIng Chou who kept working on this project for 6 years.
2
9 Jul 2019
Rest In Peace.
9 Jul 2019
We are at a loss of words. May she rest in peace. Our thoughts are with her family, friends and colleagues. Let us remember SUZANNE as the phenomenal thinker, mother and human being she was... mpi-cbg.de/news-events/lates…
1
Salic Lab retweeted
5 Jul 2019
Please share this message to anyone in #cretegreece or surrounding regions m.facebook.com/story.php?sto…
3
142
31
5 Jul 2019
Please RT/share! šŸ™.
4 Jul 2019
With a heavy heart we have to inform you that SUZANNE is missing from her hotel @orth_acad_crete since Tuesday. She was attending a meeting in Kolymbari, Crete. Search is on in full swing. Please spread this to reliable networks and PRAY for her safe return.(1/2)
3
1
Salic Lab retweeted
More exciting news! Former postdoc Long Li has struck out on his own with great success! Here’s his first #cryoEM structure: a complex of SecA and SecY translocating a polypeptide chain substrate. nature.com/articles/s41467-0…
9
30
27 Jun 2019
Congratulations to Ed and Zhejian! #cdc48 #cryoEM
We’re thrilled to share the #CryoEM structure of the Cdc48-UN complex bound to and unfolding a polyubiquitinated substrate! Cdc48 first unfolds a K48-linked ubiquitin moiety allowing the processing of diverse substrates. Congrats to Zhejian and @cryoET! science.sciencemag.org/conte…
1
18 May 2019
A very comprehensive review! #hedgehog šŸ¦”
A review from our own Jenn Kong on biochemical mechanisms of Hedgehog signaling, written with Christian Siebold, is out in Development-- includes an analysis of the many patched and smoothened structures. @Dev_journal dev.biologists.org/content/1…
5
29 Apr 2019
Wnt3 with Fz8 CRD 🐸nature.com/articles/s41594-0…

5
11
Salic Lab retweeted
15 Apr 2019
A fully referenced guide to making your lab more nurturing, collaborative and people-centred, courtesy of @ftmaestre. journals.plos.org/ploscompbi…

1
6
11
15 Apr 2019
Baby Smo blossoms, Now the spring is here to stay, When will petals fall? #happystpatricksday #BostonMarathon #BostonStrong
6
2 Apr 2019
Congratulations!
26 Mar 2019
Congratulations!
A big congratulation to Prof Stephen Harrison who will receive Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research "for his fundamental and far-reaching studies of protein structure using X-ray crystallography" tonight during an award ceremony at @BrandeisU
2
20 Mar 2019
Congratulations to Yanyan and Ben! Very nice work!
2
19 Mar 2019
Team Steptonemes taking on the Take the Stairs challenge @HarvardChanSPH. @kornberg_t look closely!
3
18 Mar 2019
Celebration time! Congratulations Dr. Petrov! #patched
1
7
18 Mar 2019
Very proud of our Kostadin! #patched #thesisdefense #phd
13
15 Mar 2019
Congratulations, Marco!
We're excited to share the newest research from our lab! In collaboration with @JoeLoparo, we use smFRET to observe the conformational changes of the AAA ATPase SecA as it translocates a model substrate through the SecY channel. emboj.embopress.org/content/…
Salic Lab retweeted
On #InternationalWomensDay, we’re celebrating women in the Harvard Medical School community who are making a difference in the world
70
195
7 Mar 2019
Team Cytomeme at the Cell Bio tri lab trivia night, with @RapoportLab and Liberles lab #TriviaNight
6