@SaricLab profile picture
Andela Saric @SaricLab

Prof of Bio & Soft Matter Physics. Living @ISTAustria; Associated @UCL Physics & @LMCB_UCL. Simulations not animations.

Joined September 2019
  • Tweets 667
  • Following 761
  • Followers 1,978
54 Photos and videos
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Andela Saric@SaricLab
12 Aug 2024
Relaxing #beachread 🏝️: filaments that grow and shrink by burning energy🔥, death💀, assembly, division ring formation 💍, and more in our new paper in @NaturePhysics nature.com/articles/s41567-0…. Great collab with @nartimsoole & @seamus_holden , led by soon-doctor @vainhilla96. ⤵️

Self-organization of mortal filaments and its role in bacterial division ring formation

Nature Physics - Treadmilling of cytoskeletal filaments is crucial for their functional self-organization. Now the mechanism underpinning this collective organization is shown to be the dissolution...

nature.com
Christian Vanhille Campos@vainhilla96
12 Aug 2024
Did you know cell filaments love to treadmill? 🔄 They grow and shrink on opposite ends and burn energy doing it! But why? How does it drive self-organisation and bacterial division? Dive into our new publication ft. @SaricLab @nartimsoole @seamus_holden labs to find out! 🧫🔬🖥️
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Andela Saric retweeted
Francesca Bottanelli@Fran_Bottanelli
11 Nov 2024
Registration is open for the 2025 iteration of the wonderful @EMBOevents workshop on cell polarity and membrane dynamics #EMBOcellPolarity25 I am organizing with Ed Munro! Wonderful lineup wonderful please sign up and RT meetings.embo.org/event/25-c…

Cell polarity and membrane dynamics

The ability of cells to polarize is essential for organismal development and physiology, and its impairment underlies numerous diseases. The establishment and maintenance of cell polarity requires a …

meetings.embo.org
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ComeInCell@ComeInCell
10 Dec 2024
Are you a fan of #ComputationalBiophysics?🖥️ The @SaricLab at the #ISTA is seeking a talented #PhDcandidate to investigate the fascinating interplay between #MolecularCondensates and #CellMembranes. Check our #PhDposition: comeincell.org/dc12-in-silic… #MSCA #ComeInCell
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Laura Alvarez@LauraAlvarez_F
10 Dec 2024
New edition of Interdisciplinary challenges (IntCha25) on physics of complexity and life will take place at Heidelberg in 2025 embl.org/about/info/course-a… @embl So proud the event keeps gathering ECR for rich exchanges @Dmichiel1 ready for the 10th anniversaire? Previous Editions👇

Interdisciplinary challenges in the physics of complexity and life 2025 (IntCha25)

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Thank you @AllenInstitute for seeing the magic in #membranebiophysics 🪄✨ We’re thrilled happy to be a part of this cohort!
allen institute@AllenInstitute
3 Dec 2024
Replying to @AllenInstitute
Using simulations, synthetic cells, and live archaeal cell communities, @SaricLab, @KGoepfrich, and Buzz Baum are challenging the assumption that the cell membrane is passive and only changes shape when acted upon. #FrontierScience
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ISTAustria@ISTAustria
3 Dec 2024
Congratulations to Anđela Šarić @SaricLab on being named an Allen Distinguished Investigator by @PGAFamilyFdn! She will lead an international collaboration, funded with $1.5 million, to investigate how chemically active membranes influence cell shape. 🔗 bit.ly/3B65vJc
ISTA Professor Anđela Šarić © ISTA

ALT ISTA Professor Anđela Šarić © ISTA

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ComeInCell@ComeInCell
27 Nov 2024
🤩 Exciting milestone for the #MSCA Doctoral Network #ComeInCell! Today we held our kickoff meeting to drive this groundbreaking project forward. Stay tuned for insights into #SyntheticBiology, #MembraneCondensates, #NeurodegenerativeDiseases, #MembraneTrafficking & more! 🔬✨
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Dimova Lab now at @DimovaLab.bsky.social@DimovaLab
4 Nov 2024
📢 Open PhD position as part of #MSCA network of 17 students @ComeInCell Interested in exploring membrane stability/repair & #condensates ? Check out & apply: 👉bit.ly/4fd8HRU The project will include secondments at @SaricLab, @MarquesLab & @NatureComms
https://doi.org/10.1038/s41586-023-06726-w

ALT https://doi.org/10.1038/s41586-023-06726-w

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Schwille Lab@SchwilleLab
25 Oct 2024
We're hiring for a MSCA PhD position! @ComeInCell We're curious about how biological condensates can be actively targeted to membrane surfaces with the thoroughly mastered self-assembling protein machinery. Check out the project at comeincell.org/dc03-active-s…
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Montenegro Lab@MontenegroLabo
28 Oct 2024
The ITN ComeInCell 🧫comeincell.org is UP sand running! Interested in synthesizing life-like systems from the bottom up? 🔊Apply now to the 2 PhD positions that we offer @ciqus within an outstanding network!! RT is highly appreciated! ⏰👉 usc.es/ciqus/es/formacion-y-…
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ComeInCell@ComeInCell
30 Oct 2024
We're super excited to launch ComeInCell- a doctoral network aimed to develop advanced cellular mimics that integrate functional membrane structures and biomolecular condensates. With a team of 14 PIs and 13 associated partners, this will be an exciting journey!
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Sandhya Koushika@WormlockHolmes
24 Oct 2024
Archeal monolayer membrane properties. Interesting work from @SaricLab. Are there implications for origin of life? biorxiv.org/content/10.1101/…

Stability vs flexibility: reshaping monolayer and bilayer archaeal membranes in silico

Across the tree of life, distinct designs of cellular membranes have evolved that are both stable and flexible. In bacteria and eukaryotes this trade-off is accomplished by single-headed lipids that...

biorxiv.org
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Miguel Amaral@miggral
24 Oct 2024
Did you know there are more than bilayer #membranes in nature? Meet the #archaeal monolayer and its surprising mechanical properties! New #preprint! (1/7)
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Andela Saric@SaricLab
22 Oct 2024
A great 🇬🇧-🇦🇹team of @BillieMeadowcr1 (currently cycling 🚴‍♀️ across 🇺🇸) @IvnPla @v_sorichetti and Eryk teamed up with with @NargessKGharibi and @YanlanMao to simulate collagen-iv remodelling under strain and enzymatic activity. @ISTAustria @LMCB_UCL @UCL_IPLS More ⬇️
Ivan Palaia@IvnPla
22 Oct 2024
Collagen-IV networks rule the #mechanics of our epithelia, but we know little about how they reshape. Our new preprint (with the 1st coarse-grained MD models of #collagen-IV!) shows how consuming energy during remodelling might make the difference: 📑tiny.cc/s6fqzz 🧵
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Andela Saric@SaricLab
22 Oct 2024
Apply! 📝
ISTAustria@ISTAustria
10 Sep 2024
Take your career to the next level: #FacultyCall @ISTAustria is open! We're seeking exceptional group leaders in #chemistry, #ComputerScience, #DataScience, #EarthScience, #LifeSciences, #mathematics, and #SoftMatterPhysics to join our institute. Apply 🔗 bit.ly/47mxEre
📸 © Josef Herfert | ISTA

ALT 📸 © Josef Herfert | ISTA
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Andela Saric@SaricLab
18 Oct 2024
New PhD in the family!: Chris Vanhille Campos @vainhilla96 🍸🥂🧉🧁. Chris was our stellar ☄️💫 student with many passions — from bacterial division, to vesicle reshaping, condensates, self-assembly, guitar, icey Danube 🧊, braving bears, to making softies @ISTAustria happy 🍧
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Andela Saric@SaricLab
18 Oct 2024
He’s currently travelling around South Korea 🇰🇷🍜 before continuing his research path. ⛰️Huge thanks to Karsten Kruse and Philip Pearce @pearce_maths for being on his committee @UCL_IPLS , and looking forward to all the great things he’ll do in the future.
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Ivan Palaia@IvnPla
17 Oct 2024
The actin #cortex is attached to the #membrane via linking proteins. When these linkers get trapped in the cortex meshes, actin jams🚧, #contractility stops🛑 and cells polarise☄️Exciting collaboration ( real fun!) with @diz_lab @TesoroRuben @SaricLab 📑biorxiv.org/content/10.1101/…

Diz-Muñoz Lab@diz_lab
15 Oct 2024
New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging! We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking. biorxiv.org/content/10.1101/…
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Andela Saric retweeted
Diz-Muñoz Lab@diz_lab
15 Oct 2024
New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging! We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking. biorxiv.org/content/10.1101/…

Caging of membrane-to-cortex attachment proteins can trigger cellular symmetry breaking

To migrate, divide, and change shape, cells must regulate the mechanics of their periphery. The cell surface is a complex structure that consists of a thin, contractile cortical actin network...

biorxiv.org
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