Schwab lab at the Department of Neurology - University Clinics Muenster, Germany. Clinical & Translational Neuroimmunology.
Joined April 2019
- Tweets 54
- Following 58
- Followers 70
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Jun 4
It was a long road, but happy that it’s finally out. The scientific results of our SMILE trial showing that MS patients have a blunted response to UVB light. In them its effects stay in the skin and do not translate systemically. link.springer.com/article/10…
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Jan 23
Happy to share our new paper on the effects of Cladribine on the T and Bcell repertoire and how they translate to clinical efficacy. onlinelibrary.wiley.com/doi/…
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24 Sep 2025
Our new study shows that natalizumab treatment gap not only changes serum biomarkers (e.g. sVCAM-1), but also (subsequently) CSF composition, suggesting that renewed immune infiltration into the CNS and other tissues might play a role in reducing PML risk. onlinelibrary.wiley.com/doi/…
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31 Jul 2025
Our paper is out: the first genetic treatment response biomarker in MS. A finding only made possible by AIRRseq. This was a truly collaborative effort with @jsabatino37 @hwiendl @AdaptiveBiotech and is a huge step towards personalized medicine.
thelancet.com/journals/ebiom…
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11 Jul 2025
Our new AIRR paper alongside Ocrelizumab, thanks to @NFDI4Immuno and the whole team! cell.com/iscience/fulltext/S…
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18 Jul 2024
The next chapter in our continued effort to understand EBV and MS: Broader anti-EBV TCR repertoire in multiple sclerosis: disease specificity and treatment modulation academic.oup.com/brain/artic…
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Schwab Lab retweeted
11 Jul 2024
Structure-based prediction of T cell receptor recognition of unseen epitopes using TCRen. Yes, it works: pubmed.ncbi.nlm.nih.gov/3898…
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24 Jun 2024
Rare diseases need some attention, too.
Chemokine-mediated cell migration into the central nervous system in progressive multifocal leukoencephalopathy: Cell Reports Medicine cell.com/cell-reports-medici…
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Schwab Lab retweeted
4 Jun 2024
Glad to finally be able to showcase our #TCR-#epitope annotation tool DETECT and the cool results we have gotten with it at the @airr_community #AIRRC7 conference!
And as of now you can use it yourself!
4 Jun 2024
We just launched ImmuneWatch DETECT!
immunewatch.com/news/introdu…
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Schwab Lab retweeted
21 Feb 2024
AIRR Community Meeting VII – Learnings and Perspectives: antibodysociety.org/the-airr…
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8 Feb 2024
Transcriptomics reveals CSF cellular composition in multiple sclerosis but detects no viral RNA
New scientific commentary by Nicholas Schwab tinyurl.com/nmw5dej8
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10 Jan 2024
I wrote a commentary about a new MS CSF scRNAseq study that was recently published in @Brain1878 Transcriptomics reveals CSF cellular composition in multiple sclerosis but detects no viral RNA academic.oup.com/brain/artic…
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Schwab Lab retweeted
20 Dec 2023
Our #OpenAccess paper on human CNS #macrophages went online today. It was a multi-year collaborative effort between clinician scientists from #Neuropathology #Neurosurgery #Oncology and #gynacology. It struck with the question: what are the phenotypes of human CNS macrophages? /1
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8 Nov 2023
The new special issue of #ScienceTranslationalMedicine is out! This issue features a collection of studies and articles exploring frontiers in #neuroimmunology and the role of the immune system in neurological conditions such as Parkinson's disease.
scim.ag/4KN
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8 Nov 2023
I wrote a review in @ScienceTM with my long-time collaborator @hwiendl about what we can learn about CNS immunity when we look closely at patients treated with interventions that target BBB trafficking. science.org/doi/10.1126/scit…
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23 Oct 2023
Beautiful example of bedside -> bench -> bedside #Tcell immunology for the treatment of #autoimmunity
nature.com/articles/s41591-0…
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Schwab Lab retweeted
5 Sep 2023
Also included is an exciting session devoted to identify the obstacles in turning AIRR-seq into a diagnostic tool
5 Sep 2023
The AIRR Community Special Event 2023 – Zooming in to the Community II - WG/SC updates & discussion is approaching!
Registration link available here:
antibodysociety.org/the-airr…
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3 Jul 2023
A new episode of #OnAIRR - the podcast of the AIRR Community is available. We discuss AIRR-seq, machine learning and disease diagnostics with @zazius, @ScottBoydLab. Subscribe and listen in your favourite app or grab the episode here: onairr.airr-community.org
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25 Apr 2023
A new episode of #OnAIRR - the podcast of the AIRR Community is available. Prof Xenophon Papademetris, @YaleRadiology, USA, introduces Software as a Medical Device. Subscribe and listen in your favourite app or grab the episode here: onairr.airr-community.org
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