Opinions are my own.
Joined October 2018
- Tweets 460
- Following 395
- Followers 591
- Likes 19,787
107 Photos and videos
Pinned Tweet
30 May 2022
Our work on ab initio phasing #MicroED data is now published @naturemethods! Big thanks to @markherzik @_KevinCorbett for writing an awesome News & Views (and Mark for reviewing the work). Big thanks to @gonenlab @maxclabbers and Johan for their hard work! nature.com/articles/s41592-0…
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Mike Martynowycz retweeted
18 Jul 2025
Another fantastic results published in #JACS. This work shows a great potential of #microED for studying mineralogical and geological samples. ED data were acquired on our Glacios at CeNT UW. pubs.acs.org/doi/full/10.102…
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5 Jul 2025
🍃➡️🧬 First paper from the Martynowycz Lab!
Spontaneous seed-protein nanocrystals → 0.85Å ab-initio structure of crambin by #MicroED No crystallization screens, no MR bias.
Watch the diffraction-to-density movie & grab the preprint below!
biorxiv.org/content/10.1101/…
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Mike Martynowycz retweeted
2 Apr 2025
Congratulations to Judge Susan Crawford on her victory, and to the people of Wisconsin for electing a judge who believes in the rule of law and protecting our freedoms.
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Mike Martynowycz retweeted
What holds your eye lens together? UCLA scientists along with now UB-HWI faculty found out! Using advanced microcrystal electron diffraction, they solved the structure of the abundant lens protein MP20. nature.com/articles/s41467-0…
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Mike Martynowycz retweeted
26 Mar 2025
Super stoked that this study is finally out
Heroic effort from several people and of course #cryoem #MicroED #FIB 👍👍
Structure of the lens MP20 mediated adhesive junction | Nature Communications
nature.com/articles/s41467-0…
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Mike Martynowycz retweeted
Researchers from UCLA and UB-HWI have pushed the boundaries of electron crystallography, achieving sub-atomic resolution using energy-filtered #MicroED #CryoEM. This improves structural detail, advancing drug discovery and biomolecular research. nature.com/articles/s41467-0…
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Mike Martynowycz retweeted
6 Mar 2025
Now most folks cant tell the difference between an Xray diffraction pattern and #MicroED 😁
Behold 0.9Å 😍
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6 Mar 2025
Our latest work shows how energy filtering, PFIB, and direct electron detection unlock sub-atomic resolution for #MicroED! 🎯
Great work from @maxclabbers and JohanHattne back when I was with @gonenlab at @BC_UCLA. Excited to bring this capability to @UBuffalo!
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Mike Martynowycz retweeted
4 Mar 2025
Happy to share high throughput ligand and inhibitor screening against enzymes using MicroED. Drug discovery based on structures
Ligand Screening and Discovery using Cocktail Soaking and Automated MicroED | bioRxiv biorxiv.org/content/10.1101/…
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Mike Martynowycz retweeted
5 Mar 2025
Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @CellCellPress cell.com/cell/fulltext/S0092… . What’s new?
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Mike Martynowycz retweeted
4 Mar 2025
Probing ion channel dynamics at atomic resolution using vanishingly small crystals and #MicroED.
Yes, dynamics can be probed even qith crystals...
High-throughput MicroED for probing ion channel dynamics | bioRxiv biorxiv.org/content/10.1101/…
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Mike Martynowycz retweeted
4 Mar 2025
Whats the best slit width for your energy filter? @maxclabbers systematically tested the settings. The results may surprise you...
Characterization of energy filtering slit widths for MicroED data collection | bioRxiv biorxiv.org/content/10.1101/…
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Mike Martynowycz retweeted
19 Jan 2025
The 7th Challenges in Structural Biology Summit will be 9/9-12/25 at UCLAs Lake Arrowhead Resort. @BrentNannenga and I are taking nominations for speakers. Please write, self nominations are OK. Focus is on methods and challenges. Everyone speaks. Limited to 50 speakers/attendees
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8 Jan 2025
I’m happy to share that @HWMRI has merged with @UBuffalo. My lab will stay at HWI, and my title is changing. I’m starting a new position as a tenure track Assistant Professor at the Jacob’s School of Medicine at the University at Buffalo!
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Mike Martynowycz retweeted
7 Jan 2025
#FeaturedProtocol this week from @gonenlab: The preparation of #microcrystals for #CryoEM enables the acquisition of diffraction patterns from nanometre-sized samples go.nature.com/4j47NcK See also accompanying News & Views
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Mike Martynowycz retweeted
7 Jan 2025
@WiwiSFC @maxclabbers @ScienceMick @calliesayshi @Anna_Shiriaeva_ cody gillman and many others that contributed over the years to this collective #cryoem #MicroED knowledge - now at your fingertips 😍
7 Jan 2025
#FeaturedProtocol this week from @gonenlab: The preparation of #microcrystals for #CryoEM enables the acquisition of diffraction patterns from nanometre-sized samples go.nature.com/4j47NcK See also accompanying News & Views
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