The Scintillon Institute for Biomedical and Bioenergy Research is a 501(c)(3) non-profit research institute that is developing biologically-based technologies.
Joined October 2014
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A teaser of what Scintillon’s fundamental research can lead to new aging and cancer drugs from today’s special seminar by Dr. Valentin Cracan.
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Join us at Scintillon this Friday, 1 p.m., for an in-person seminar by Dr. Valentin Cracan to learn about his development of xenotopic tools for investigation of the role of redox imbalance in metabolic decline linked to aging, with fascinating potential for aging intervention.
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scintillon.org/2026-sif-regi…, Dr. Peter Adams on aging and Dr. Hideyuki Okano, President of International Society of Stem Cell Research (ISSCR) will give keynote speeches on Aging and iPSC and cell therapy approval. This FRIDAY at Catamaran Hotel in San Diego scintillon.org/2026-1st-scin…
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Our 1st annual Scintillon Institute Innovator Forum at the Catamaran Hotel in Pacific Beach is taking place this Friday, March 27! Come join us!
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Come join us for our 1st annual Scintillon Institute Innovator Forum at the Catamaran Hotel in Pacific Beach on March 27. This year, we aim to bring together colleagues from academia and industry to discuss aging and rejuvenation research.
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Dr. Peter Adams, Director of the Cancer Genome and Epigenetics Program at Sanford Burnham Presbys and PI of the San Diego Tissue Mapping Center, will be a speaker for our 1st annual Scintillon Institute Innovator Forum on 3/27 at Catamaran Hotel in PB.
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Scintillon Scientific Advisory Board Member Professor Hideyuki Okano, President of the International Society for Stem Cell Research, will be a speaker for our 1st annual Scintillon Institute Innovator Forum on 3/27 at Catamaran Hotel in Pacific Beach.
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Our 1st annual Scintillon Institute Innovator Forum will be held on March 27 at the Catamaran Hotel in Pacific Beach. This meeting aims to engage colleagues from academia and industry to discuss innovative topics such as aging and rejuvenation research.
lnkd.in/gRjWquEx
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Congratulations to @VFCracan and colleagues for developing a genetically encoded tool based on a bifunctional enzyme that can restore redox imbalance and modulate lipid metabolism in vitro and in a mouse hepatic steatosis model.
rdcu.be/e4cTK
Feb 22
I am excited to share our newest paper, "A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity," which is now live in @NatMetabolism! This study was led by outstanding members of my lab @XingxiuPan and @smunan1995, in close collaboration with the @hardikshah42 lab at @UCCancerCenter and the @russpgoodman lab at @MassGenBrigham. In this study we present a genetically encoded tool based on a bifunctional enzyme that can regenerate NAD⁺ while simultaneously executing an engineered glycerol shunt. We used this tool, which we call CrGPDH, to restore redox imbalance and modulate lipid metabolism in vitro and in a mouse hepatic steatosis model. 🧵
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Scintillon Center for Resilience to Aging was presented at the Biophysical Society Annual Meeting 26in San Francisco. Learn more about our center's innovations at Scintillon's 1st Innovator Forum in San Diego on March 27th lnkd.in/gRjWquEx #aging, #Scintillon, #BPS2026
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5 Nov 2025
Congratulations to our faculty, Dr. Brian Lawson, for receiving a Healthy Longevity Catalyst Award from the National Academy of Medicine for developing microglia with chimeric antigen receptors as treatment for multiple sclerosis.
scintillon.org/brian-lawson-…
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22 May 2025
Prof. Guoping Fan of Scintillon has published a new paper in Molecular Cell linking a DNA epigenetic enzyme to mRNA modification and mitochondrial function, with implications for neurodegenerative diseases such as Parkinson’s and Alzheimer’s, and aging.
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19 May 2025
Panda Express Community Programs community-fundraiser.com/vir…
Scintillon faculty Drs. Yun Yung and Jiwu Wang serve on the SAB of the Hydrocephalus Association and encourage everyone to support efforts toward finding effective treatments and, ultimately, a cure for hydrocephalus.
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Scintillon Institute retweeted
4 Apr 2025
NEWS&VIEWS | X Pan & @VFCracan (@Scintillon, @scrippsresearch)
A new study reveals that in contrast to other #cancer types, translocation renal cell carcinoma is rewired towards an #OXPHOS state, which renders it vulnerable to NADH reductive stress.
nature.com/articles/s42255-0…
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Scintillon Institute retweeted
1 Apr 2025
Metabolic dysregulation is a driving force of aging.
Enzymes from lower organisms—such as bacteria and yeast—may be able to reverse age-associated metabolic changes in humans, a new study finds. @VFCracan @Scintillon @Aparhit @AgingPitt @PittDeptofMed scim.ag/4i31Lrr
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16 Oct 2024
Scintillon and #scrippsresearch scientists uncover a role for non-coding RNAs in Autism Spectrum Disorders. Using patient-derived stem cells, the team discovers aberrant neuronal activity could be partly rescued by NMDA-receptor blocker Nitrosynapsin. scintillon.org/news/nitrosyn…
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16 Jul 2024
Scintillon welcomes three new faculty members, Drs. Guoping Fan, Alexey V. Terskikh @_terskikh and Tal Teitz who have joined the institute to strengthen our research focus on healthy aging and neurological diseases.
scintillon.org/faculty-recru…
ALT Drs. Guoping Fan, Alexey Terskikh, Tal Teitz
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Scintillon Institute retweeted
15 May 2024
The scientific founder of K Pharma, Dr. Hideyuki Okano, the next President of ISSCR, has developed an iPSC differentiation method using transgene expression. Allele has developed transcription factor-directed differentiation protocols, but with mRNA. allelebiotech.com/allele-and…
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15 May 2024
Scintillon Institute Associate Professor Albert Chen @aic2002 has been awarded a grant from the @NIH @NIDDKgov to study the link between the cerebellum, dopamine signaling and obesity.
scintillon.org/cerebellum-ob…
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