PhD student studying tissue engineering at the centre for the cellular microenvironment (CeMi) at the University of Glasgow. Also a member of the lifETIME CDT.
Joined October 2020
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📢NEW PAPER📢 "Synthetic peptide hydrogels as a model of the bone marrow niche demonstrate efficacy of a combined CRISPR-CAR T-cell therapy for acute myeloid leukaemia" in biomaterials! doi.org/10.1016/j.biomateria…
@theglasgowcemi
#research #tissueengineering #AML #CRISPR #CART
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I was delighted to attend the #TCESxCDTs conference this week, in which I had the pleasure of presenting my research on developing a synthetic bone marrow niche for haematopoietic stem cell maintenance #phd @CDTLifETIME
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(1/3) Developing an artificial BM niche
Haematopoietic stem cells (HSCs) produce blood and immune cells. Mutations in HSCs lead to diseases such as leukaemia and sickle cell anaemia. HSC research promises to help treat these diseases #TCESxCDTs
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(2/3) HSCs quickly lose their stemness when removed from the BM niche, limiting HSC research. My project, in collaboration with @MancBIOGEL, aims to develop an artificial BM niche that can grow HSCs in the lab #TCESxCDTs
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(3/3) If successful, this niche will revolutionise our understanding of the BM niche and associated diseases, as well as satisfying the demand for HSCs for research and clinical uses #TCESxCDTs @theglasgowcemi
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Seb retweeted
16 May 2022
Delighted to share our new review from @theglasgowcemi - a deep dive into bone marrow niche biology, and the complexity of engineering the BM niche in vitro. Fab team effort led by @Yinbo_Xiao. @Chanelle_McG, @Seb_sci, @ManuelMime, @DalbyMatthew doi.org/10.1016/j.biomateria…
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google.com/amp/s/www.technol… This is very cool! Is AI predicting results going to replace lab work? And how long before this can be applied to all experiments? What will this mean for the research community?