PhD Candidate at UNC, Chapel Hill 🔬🧠👩🏻‍🔬 Looking at #organelles during #neurodegeneration with #multispectral #microscopy #WomenInSTEM

Joined April 2020
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Shannon Rhoads retweeted
During #NeuronalDifferentiation, #organelles dramatically reorganize. #Microtubules are essential tracks for transport. But are they just highways, or can they instruct organelle behavior? Are tubulin modifications a regulatory code that guides organelle position or function?1/9
Tubulin acetylation governs organelle remodeling and lysosomal reformation during neuronal differentiation biorxiv.org/content/10.64898… #biorxiv_cellbio
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Shannon Rhoads retweeted
Cells come in many shapes and sizes, with diverse physiological functions. But how do #organelles and their interaction networks remodel during #differentiation of stem cells into different cell types? Here’s what we discovered about neuronal differentiation: 1/13
Organelle communication networks rewire to support lipid metabolism during neuronal differentiation biorxiv.org/content/10.64898… #biorxiv_cellbio
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Shannon Rhoads retweeted
Nominations are open for the Index of Inspiring Black Scientists! Help us build a global, searchable resource of inspiring Black scholars in STEM. Eligibility: Self-identified Black scholars at any career stage! Nominate here: forms.gle/7nq5s2xBENUFvitY9
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Come see me at #CellBio2024!! I’ll be presenting on our recent pre-print using imaging-omics to characterize organelle differences between neurons and astrocytes!
Cohen lab will be well represented at #CellBio2024! If you love #Organelles, #MembraneContactSites, and/or #Neurons and #Astrocytes, please come say hello!
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Shannon Rhoads retweeted
Please read our latest newsletter in which we launch the 2024 Feast for Families program, this year our goal is over $10,000, so that we can provide over 100 meals to our NC ALS community. If you would like to donate and follow the progress. Details here: alsnc.org/october-2024-newsl… #ALSNC #ALSUnited #Thanksgiving2024
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Wow, I love this and am glad the topic has been discussed within such a large group and compiled so nicely. Great work!! 🎉
New from me and a huge cast of amazing bioimage analysts in @J_Cell_Sci - - "The crucial role of bioimage analysts in scientific research and publication" journals.biologists.com/jcs/… . Hop into 🧵to learn more! (1/x)
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Check out our preprint using imaging-omics to characterize the #OrganelleSignature - the morphology interactions & distribution of #ER❤️ #Lysosomes🩵 #Mitochondria💚 #Peroxisomes🧡 #Golgi💛 & #LipidDroplets🩷 - of live #neurons and #astrocytes! doi.org/10.1101/2024.10.30.6… 🧵1/11

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Our dataset includes 173 Z stack and 99 timelapse multispectral images and is accompanied by a quantitative dataset of 1418 organelle signature metrics. The data are on BioImage Archive (ebi.ac.uk/biostudies/BioImag…) for further exploration, analysis and hypothesis generation. 10/11
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A huge THANK YOU🎉 to co-authors at @UNC_SOM (@ValerieDon83999 @ChihHsuanHsu1 @MC_Zanellati @ToddCohen27 @cohenlaboratory and more); collaborators (@DataTecnica); @FishCsCells and UNC’s Hooker Imaging Core for expert microscopy advice; @NIH and @ChanZuckerberg for funding!! 11/11
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Shannon Rhoads retweeted
Cool story from @YoniMalis and @KoretHirschberg on the role of Rab1 in targeting proteins from the #EndoplasmicReticulum to #LipidDroplets
30 May 2024
Happy to share that our #Rab1 - #LipidDroplets paper is now published in @ScienceAdvances. We show that Rab1b regulates the recruitment of the essential lipid synthesizing enzyme #DGAT2 from the ER to the LD surface in order to promote their growth. We also link Rab1b’s role in LDs to the pathogenesis of Warburg Micro syndrome. @KoretHirschberg @EllaSklan @TAUMedFaculty science.org/doi/10.1126/scia…
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Shannon Rhoads retweeted
5 Apr 2024
How can machine learning help you to analyze your microscopy images? Find out at the "Deep Learning for Microscopy Image Analysis" course at the @MBLScience in Woods Hole from Aug 21-Sep 5! Applications are due 🚨 April 17 🚨 Read on for more! 👇 mbl.edu/education/advanced-r…

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