Embracing a multitude of computational methods, biomedical data, & unique perspectives to advance precision medicine - & having a lot of fun in the process!

Joined September 2021
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Come join us! Info on open postdoc positions below 🧬💻🥳
The @SirotaLab has openings for postdocs who are interested in exploring one or more of the following research areas: electronic health records, multi-omics integration, pregnancy, endometriosis, autoimmune diseases, and Alzheimer’s disease. See below for contact info. Please RT!
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It is with a mix of emotions that I finally announce this work, my very last w/ @atulbutte. Atul believed in the power of open data and our ability to learn from the data we already have to improve healthcare now. This work is a tribute to this belief, made possible by his career
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Tremendous thanks to Martin Papenberg, Cheng Wang, MaĂŻgane Diop, Syed Hassan Bukhari, Boris Oskotsky, Brittany Davidson, Kim Chi Vo, Binya Liu, Juan C. Irwin, Alexis J. Combes, Brice Gaudilliere, Jingjing Li, David K. Stevenson, Gunnar W. Klau, Linda C. Giudice, and Marina Sirota
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Our Anticlust article by Papenberg et al. is now published in Cell Reports Methods, cell.com/cell-reports-method…, and featured on their cover, cell.com/cell-reports-method… 🎉 @UCSF_BCHSI @HHU_de @UCJointCPH @StanfordMed
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Sirota Lab at UCSF retweeted
Today, tech & health communities remember life of @atulbutte & celebrate @UCSF_BCHSI 10 years. Colleagues revealed a single person & approach - optimism-generosity-expertise - can shape the future of an industry. His protege @msirota84 of his words to her: Take it, run with it!
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Sirota Lab at UCSF retweeted
Train UCSF-GPT at Cost of a Costco membership... Rohit Vashisht @UCSF_BCHSI
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Sirota Lab at UCSF retweeted
Scientists at Gladstone and @UCSF have identified a combination of two anticancer drugs that the researchers suggest may reverse the changes that occur in the brain during Alzheimer’s disease, potentially slowing or even reversing its symptoms. bit.ly/3Jhfgbi

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Using big data to tackle endometriosis! Umair Khan from our lab combined AI and large-scale health records to uncover new insights into a disease that affects millions, out in Cell Reports Medicine today. @SirotaLab @UCSF_BCHSI @CellPressNews ucsf.edu/news/2025/07/430471…
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Sirota Lab at UCSF retweeted
What does the next 10 years of @UCSF_BCHSI will look like? @vivicality
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Sirota Lab at UCSF retweeted
We are excited to introduce a dedicated Agent Track as part of the SEA-AD DREAM challenge! Informational webinar on Monday 8/11, 3pm PT synapse.org/Synapse:syn66496… Join our worldwide challenge leveraging #snRNAseq data & cutting-edge #AI/#ML approaches. #Alheimers #neuropathology
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Sirota Lab at UCSF retweeted
The SEA-AD DREAM Challenge is now live on @SynapseOrg🧠🧑‍💻 Join this worldwide challenge leveraging single-cell data and cutting-edge AI/ML approaches. P.S. An exciting announcement will be coming - stay tuned! #MachineLearning #Alzheimer #OpenScience synapse.org/Synapse:syn66496…
Excited to announce the SEA-AD DREAM on @SynapseOrg! Join the global research community to tackle AD using single cell data and innovative AI/ML solutions. Let’s accelerate discovery together! synapse.org/Synapse:syn66496… @AllenInstitute @DR_E_A_M @Sagebio @SirotaLab @UCSF_BCHSI
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Sirota Lab at UCSF retweeted
21 Jul 2025
FDA-approved cancer drugs reversed brain changes tied to Alzheimer’s and brought back memory. UCSF and @GladstoneInst researchers combined patient data with genetic analysis to fast-track a potential new treatment. tiny.ucsf.edu/579NOK

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24 Jun 2025
The UCSF community mourns the passing of Atul Butte, MD, PhD, a bold thinker, inspiring mentor and founding director of the Bakar Computational Health Sciences Institute. tiny.ucsf.edu/tGz3QY

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Sirota Lab at UCSF retweeted
.@msirota84 on how she and colleagues used the EHR, genetics data & @UCSF_BCHSI SPOKE knowledge graph to improve predictive power for #Alzheimer's among women, and detect links with #osteoporosis. For more research highlights, connect to CPH YouTube channel (link in bio)!
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Sirota Lab at UCSF retweeted
Today, 3/26 at 6-7pm. Join us online for this webinar! AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine
Join the @UCSF @Stanford Enact webinar on Wed., 3/26 w/ BCHSI team "AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine" @msirota84 @tomiko22 Umair Khan - Details here enactcenter.org/
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Sirota Lab at UCSF retweeted
Join the @UCSF @Stanford Enact webinar on Wed., 3/26 w/ BCHSI team "AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine" @msirota84 @tomiko22 Umair Khan - Details here enactcenter.org/
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