Embracing a multitude of computational methods, biomedical data, & unique perspectives to advance precision medicine - & having a lot of fun in the process!
The @SirotaLab has openings for postdocs who are interested in exploring one or more of the following research areas: electronic health records, multi-omics integration, pregnancy, endometriosis, autoimmune diseases, and Alzheimer’s disease. See below for contact info. Please RT!
It is with a mix of emotions that I finally announce this work, my very last w/ @atulbutte. Atul believed in the power of open data and our ability to learn from the data we already have to improve healthcare now. This work is a tribute to this belief, made possible by his career
Tremendous thanks to Martin Papenberg, Cheng Wang, MaĂŻgane Diop, Syed Hassan Bukhari, Boris Oskotsky, Brittany Davidson, Kim Chi Vo, Binya Liu, Juan C. Irwin, Alexis J. Combes, Brice Gaudilliere, Jingjing Li, David K. Stevenson, Gunnar W. Klau, Linda C. Giudice, and Marina Sirota
ALT Issue cover for Volume 5, Issue 8 Aug 18, 2025 On the cover: In this issue of Cell Reports Methods, Papenberg et al. present an anticlustering algorithm for balanced batch assignment in high-throughput sequencing studies and other applications. The cover image depicts the anticlust algorithm optimizing the assignment of units, such as samples, to balanced batches. Created with biorender.com
Today, tech & health communities remember life of @atulbutte & celebrate @UCSF_BCHSI 10 years. Colleagues revealed a single person & approach - optimism-generosity-expertise - can shape the future of an industry. His protege @msirota84 of his words to her: Take it, run with it!
ALT Marina Sirota sharing a slide about Atul's life.
Scientists at Gladstone and @UCSF have identified a combination of two anticancer drugs that the researchers suggest may reverse the changes that occur in the brain during Alzheimer’s disease, potentially slowing or even reversing its symptoms.
bit.ly/3Jhfgbi
Using big data to tackle endometriosis! Umair Khan from our lab combined AI and large-scale health records to uncover new insights into a disease that affects millions, out in Cell Reports Medicine today. @SirotaLab@UCSF_BCHSI@CellPressNewsucsf.edu/news/2025/07/430471…
We are excited to introduce a dedicated Agent Track as part of the SEA-AD DREAM challenge!
Informational webinar on Monday 8/11, 3pm PT synapse.org/Synapse:syn66496…
Join our worldwide challenge leveraging #snRNAseq data & cutting-edge #AI/#ML approaches. #Alheimers#neuropathology
The SEA-AD DREAM Challenge is now live on @SynapseOrg🧠🧑‍💻
Join this worldwide challenge leveraging single-cell data and cutting-edge AI/ML approaches. P.S. An exciting announcement will be coming - stay tuned! #MachineLearning#Alzheimer#OpenSciencesynapse.org/Synapse:syn66496…
FDA-approved cancer drugs reversed brain changes tied to Alzheimer’s and brought back memory. UCSF and @GladstoneInst researchers combined patient data with genetic analysis to fast-track a potential new treatment.
tiny.ucsf.edu/579NOK
The UCSF community mourns the passing of Atul Butte, MD, PhD, a bold thinker, inspiring mentor and founding director of the Bakar Computational Health Sciences Institute.
tiny.ucsf.edu/tGz3QY
A new study has identified FDA-approved cancer drugs that reverse gene expression signatures associated with Alzheimer’s. gladstone.org/news/combinati…
.@msirota84 on how she and colleagues used the EHR, genetics data & @UCSF_BCHSI SPOKE knowledge graph to improve predictive power for #Alzheimer's among women, and detect links with #osteoporosis. For more research highlights, connect to CPH YouTube channel (link in bio)!
Today, 3/26 at 6-7pm. Join us online for this webinar! AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine
Join the @UCSF@Stanford Enact webinar on Wed., 3/26 w/ BCHSI team "AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine" @msirota84@tomiko22 Umair Khan - Details here enactcenter.org/
Join the @UCSF@Stanford Enact webinar on Wed., 3/26 w/ BCHSI team "AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine" @msirota84@tomiko22 Umair Khan - Details here enactcenter.org/