Co-founder and CEO at OneAngstrom | I post about molecular design and #SAMSON, the integrative molecular design platform | samson-connect.net

Joined February 2012
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Big update from OneAngstrom: SAMSON 2026 R1 is here! This release brings powerful new capabilities: the Path Analyzer, the Strain Explorer, and integration of Meta’s UMA force fields - plus more improvements across the platform. We’re excited to keep pushing SAMSON forward for the molecular modeling community! Learn more: • What’s new in SAMSON 2026 R1: documentation.samson-connect… • Path Analyzer: samson-connect.net/extension… • Strain Explorer: samson-connect.net/extension… • UMA force fields: samson-connect.net/extension… #MolecularDesign #ComputationalChemistry #MolecularModeling #SAMSON #MaterialsScience #DrugDiscovery
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Couple quick tips for modeling DNA in SAMSON
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Get your very own 2 Axle Pin Beam that was featured in the summer blockbuster movie "CAD models to atomistic assemblies" samson-connect.net/documents…
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DNA structures can now be viewed directly in the #SAMSON web-app, no need to download just to check them out, so check out the Turberfield Pyramid. samson-connect.net/documents…
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A hyperscale AI datacenter consumes the power of a small power plant. A mature molecular mechanical computer might perform comparable computation on the power budget of a hearing aid with no water. That's the promise of reversible nanomechanical computing!
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Important new part! This embedded bearing allows a hexagonal shaft to rotate without complicated nanotube bearings. Check it out here: samson-connect.net/documents…
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Learn to model this 3-arm DNA tile that can self-assemble into a large hexagonal pattern. youtu.be/LJ-Anu3awRY
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Coming up 🌐
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Racks for the 32-tooth gear. There is a bushing on the other side as well, but it is a little too large. Making it smaller would be an excellent intro project for someone. samson-connect.net/documents…
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If you're interested in DNA nanotechnology and nanoscale designs, please check out Tom's incredible work!
World largest repository of Diamond and DNA nanotechnology models. All available for download. samson-connect.net/TomMoore
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World largest repository of Diamond and DNA nanotechnology models. All available for download. samson-connect.net/TomMoore
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It's a pretty straightforward leap from this TX crossover to stapling together origami. Download here samson-connect.net/documents…
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They call me One-Take Tommy. Learn DNA nanotechnology with the DPE crossover youtu.be/nBJIpBHfukg
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DAO crossover. Same as the double anti-parallel even (DAE) but now with an odd number of half-turns between crossovers. Got 10 crossovers to get though and then we'll put them together for more complex stuff. samson-connect.net/documents…
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Let's soften things up some from diamond. I'm starting a new series and part repository for DNA structures, machines, and origami. DNA is what I worked on before I got into diamond machines. Here is the first tutorial. youtu.be/Ipkd4hwkckk
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HDRIs 🥰
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Testing how materials combine with skyboxes.
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Playing with the upcoming SAMSON path tracer update. Model by @mooreth42
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Good diamondoid-machine designer rule of thumb: adding 6 rings around the circumference increases the diameter by 0.5 nm. Download here samson-connect.net/documents…
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On April 30, I’ll be hosting a webinar to introduce SAMSON 2026 - the new release of our platform for molecular modeling and simulation. This version brings major improvements across SAMSON, including new tools to help researchers move faster from structure to insight. During the webinar, I’ll show in particular how to: ✅ use the new Path Analyzer to analyze paths and molecular dynamics trajectories and generate advanced plots in just a few clicks ✅ use UMA Force Fields in interactive simulations ✅ use the new Strain Explorer to analyze ligand poses If you work in molecular design, computational chemistry, structural biology, materials science, or related fields, this session will give you a concrete look at what’s new and how it can accelerate your workflows. 📅 April 30, 2026 🕔 5 PM CET / 11 AM EST / 8 AM PST Register here: oneangstrom.com/webinar-intr… If you’d like to follow along during the webinar, you can create a free account on SAMSON Connect and install SAMSON beforehand. Excited to share what we’ve been building! #SAMSON #MolecularDesign #ComputationalChemistry #DrugDiscovery #MaterialsScience #MolecularModeling #LifeSciences #Simulation #Chemoinformatics #OneAngstrom

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