Professor of Neurology, Myologist, Myopathologist & Electromyographer at Mayo Clinic; Tweets limited to Medicine, Travel & Food.
Joined October 2019
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Inflammatory myopathies are typically associated with a myositis-specific autoantibody that determines the diagnosis and prognosis. Myositis subgroups have distinct pathomechanisms that now allow for targeted therapies.
Learn more in the Review Article “Inflammatory Myopathies” by Yves Allenbach, MD, PhD, and Olivier Benveniste, MD, PhD: nej.md/49Iy9Oo
ALT The image is a scientific illustration from a Review Article on inflammatory myopathies. It features a series of labeled diagrams and MRI images associated with different myopathy types. The diagrams show human figures with muscle weakness highlighted, and there are close-up images of muscle fibers under a microscope. The myopathy types include Inclusion-Body Myositis, Immune-Mediated Necrotizing Myopathies, Antisynthetase Syndrome, and Dermatomyositis. Diagnostic markers and affected areas are indicated.
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Teerin Liewluck, MD, FAAN, FANA retweeted
Hot off the press! Nerve biopsy is more sensitive than fat aspirate and skin biopsy for amyloid diagnosis in symptomatic ATTRv peripheral neuropathy (95% vs 48% and 53%). Great @MayoClinicNeuro enterprise collaboration and strong work from Mayo MS4 and incoming @UVANeurology star resident @APanrudkevich . @GreenJournal bit.ly/4tqCXPH
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Teerin Liewluck, MD, FAAN, FANA retweeted
I had so much pleasure to interview Dr. Margherita Milone on this group of genetically determined disorders that may present with the triade of IBM, Paget's disease, and FTD. The phenotype is variable, which makes the diagnosis challenging.
@AANEMorg
open.spotify.com/episode/4jD…
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Teerin Liewluck, MD, FAAN, FANA retweeted
May 6
Newsflash: A randomized controlled trial supports a treatment that millions of patients been using over the last 70 years!
This could have gone two ways, and speaking on behalf of everyone who cares about MG care, all I can say is... Phew!
pubmed.ncbi.nlm.nih.gov/4194…
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Teerin Liewluck, MD, FAAN, FANA retweeted
Before you diagnose CIDP:
✅ Make sure to check if the motor conduction velocity is truly in the demyelinating range. Upper limb CV should be slower than 35 m/s and lower limb less than 25 m/s. Be careful with amplitude-dependent slowing.
✅ Consider whether it's a variant — if so, be aware that these cases are more prone to misdiagnosis.
✅ Exercise caution with elevated CSF protein levels, as this finding is non-specific and should not be solely relied upon for diagnosis.
✅ Look for the presence of monoclonal gammopathy, which could indicate POEMS syndrome, AL amyloid, or IgM/Anti-MAG neuropathy.
✅ If any of these are present consider an auto-immune nodopathy: markedly elevated CSF protein (>200 Mg/dl), distal predominant weakness, CNS demyelination, nephrotic syndrome, marked hypertrophy of nerve roots and plexi, respiratory failure, or cranial neuropathy
✅ Finally, verify your diagnosis against the EAN/PNS guidelines to ensure accuracy here: live.avomd.io/algo/d483be0c-…
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Teerin Liewluck, MD, FAAN, FANA retweeted
Apr 24
#Myositis mimics are a regular challenge encountered in clinics, and critically important for our patients.
A real pleasure working with #neurology colleagues on this—highlighting practical #guidance that is especially useful for new consultants : lnkd.in/eupVTqze
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Teerin Liewluck, MD, FAAN, FANA retweeted
📄 New review in JND: Somatic instability in DM1
CTG repeat expansions:
• Grow over time
• Vary by tissue (muscle > blood)
• Are shaped by DNA repair (MMR, FAN1)
Read the open access review here: buff.ly/VcelXQu
#DM1 #RepeatExpansion #Genetics #RareDisease
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Teerin Liewluck, MD, FAAN, FANA retweeted
IVIg for CIDP: Start with the loading dose (2 g/kg), then give 1 g/kg every 3 weeks. Schedule a follow-up visit in 9-12 weeks. Treatment response should be assessed using the INCAT score (at least 1 point improvement) and/or the MRC sum score (>2 points). If there is no response, reconsider the diagnosis, as it is unlikely to be CIDP. Do not use symptom improvement or “halted progression” as proof of response. Refer to a @gbscidp center of excellence if there is no response or if there are doubts about the diagnosis.
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Teerin Liewluck, MD, FAAN, FANA retweeted
Are you finding it challenging to counsel patients with peripheral neuropathy? Interested in strategies for managing diabetic, idiopathic, and metabolic syndrome-related neuropathies? Tune into this @neuro_podcast podcast, where we dive deep into these topics. Don’t miss out! Listen on your way to the @AANmember meeting. 🤓 open.spotify.com/episode/0Tc…
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We’d like to thank the @_ENMC
& all participants for their invaluable contributions in making this workshop a success. This lay report summarizes the key discussions and outcomes of the 294th workshop on #paraproteinemia #myopathy (#SLONM & #Amyloidosis)
enmc.org/?p=11618
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Teerin Liewluck, MD, FAAN, FANA retweeted
📄 New in JND
Muscle MRI detects early, subtype-specific patterns in idiopathic inflammatory myopathies: buff.ly/ihGdZJG
✔️ Distinct signatures across IBM, DM, PM, ASYS, IMNM
✔️ Correlates with muscle strength & CK
#Myositis #MRI #Neuromuscular
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Teerin Liewluck, MD, FAAN, FANA retweeted
Why do only some cancer patients develop #paraneoplastic neurological syndromes (PNS)? 🧠
This review explores the immune mechanisms behind PNS and how tumor genetics & immune tolerance shape risk. Kudos to @AKunchok. Open access link: journals.lww.com/co-neurolog…
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I am very grateful to @_ENMC for making this 294th workshop on #paraproteinemia #myopathy possible. Thanks to all participants for great discussion and active engagement over the past 3 days.
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Teerin Liewluck, MD, FAAN, FANA retweeted
I had the pleasure to interview Teerin Liewluck @TLiewluck and Pannathat Soontrapa to discuss monoclonal gammopathies associated myopathies. These myopathies are rare yet treatable. Muscle biopsy reamains a gold standard tool for diagnosis.
@AANEMorg
open.spotify.com/episode/0y9…
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Teerin Liewluck, MD, FAAN, FANA retweeted
Dear Neuromuscular Medicine Fellowship Applicants: Apply to our program! Master EMGs, NM ultrasound, and nerve and muscle biopsy interpretation through clinical rotations, elite didactics, and 3 months of electives. We look forward to interviewing and getting to know you!
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Teerin Liewluck, MD, FAAN, FANA retweeted
🧬🚨New in @medrxivpreprint: Spatial transcriptomics reveals mechanism of autoimmunity driven by internalized autoantibodies: antibody secreting cells induce antibody internalization, disrupt autoantigen function, and drive muscle damage and inflammation
doi.org/10.64898/2026.02.14.…
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I am honored to be invited to speak at the 2026 AOMC #AOMC2026 meeting in Perth. The program looks outstanding and I am looking forward to reconnecting with colleagues from across Asia, Australia, and New Zealand. eecw.eventsair.com/ann-aomc-…
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Teerin Liewluck, MD, FAAN, FANA retweeted
If you write a review article, please try to educate the reader rather than vomiting up the literature. Many can summarize the evidence, but few can do so in an informative and didactic way. There are too many reviews out there. Try to make yours unique and meaningful.
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Teerin Liewluck, MD, FAAN, FANA retweeted
20 Dec 2025
Treatment Strategies for Sporadic Late-Onset Nemaline Myopathy
Current Treatment Options in Rheumatology 2025
link.springer.com/article/10…
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