We collaborate with national & international Doctors & Researchers around the world to help educate & provide research about #MOGAD. 501(c)3 🌺 #ViewsAreOurOwn
Joined April 2020
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363 Photos and videos
The MOG Project retweeted
May 21
✅The “H sign” in axial spinal cord MRI reflects predominant gray matter involvement and is a classic clue for myelitis.
💡It is best seen on T2-weighted images and may help distinguish MOGAD from other inflammatory myelopathies.
doi.org/10.1007/s10072-025-0…
May 20
🫣My optometrist asked me which letter I could see.
🤓My answer apparently worried him enough to recommend new glasses.
What letter do you see here? Does it suggest anything to you?
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The MOG Project retweeted
Jun 3
✅ MOG antibody-associated myelitis (MOGAD).
💡Longitudinally extensive transverse myelitis with predominant central gray matter involvement ("H-sign") should raise suspicion for MOGAD. Remember that spinal MRI may occasionally be normal early in the disease.
doi.org/10.3389/fneur.2023.1…
Jun 2
🥸A previously healthy adult presents with acute to subacute bilateral lower-extremity weakness, sensory disturbances, and urinary dysfunction following a recent infectious illness. Symptoms rapidly progress over days, prompting spinal MRI.
🥼What is your leading differential?
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The MOG Project retweeted
Jun 11
✅MOGAD presenting as ADEM with bilateral optic neuritis.
💡In children, MOGAD often shows an ADEM-like pattern with large white matter lesions, frequently involving the thalami. Optic neuritis is commonly bilateral and tends to affect the anterior optic nerve.
doi.org/10.1111/cei.13641
Jun 10
👧A 3-year-old girl presents with encephalopathy, multifocal neurological deficits, and visual symptoms.
🤔Which demyelinating disorder would you most strongly suspect based on these MRI findings?
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The MOG Project retweeted
May 31
The Italian Registry for Autoimmune Encephalitis 🇮🇹 was presented for the first time in the beautiful setting of Alghero! Thanks to all the friends and colleagues from allover Europe for making this possible💣 @neurotutto @AlvinoBisecco @MGastaldi85 @GruppoNina
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May 23
Last week, leading international experts in #MOGAD research & care gathered in Cambridge, Massachusetts for the International Expert Panel on Research Directions in MOGAD — bringing together leading clinicians, researchers, industry collaborators, & @TheMOGProject’s patient advocacy leadership to help align future priorities in MOGAD.
Discussions focused on:
✅diagnostics ✅biomarkers ✅therapeutics ✅quality of life ✅patient experiences ✅future research directions — with outcomes serving as an important document of record for The MOG Project’s global advocacy & policy work.
The panel was co-chaired by Julia Lefelar, Lisa Ryan & Leslie Hanrahan from @TheMOGProject & Dr @mlevy18 from @MGHNeurology.
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Thank you to our sponsors, @UCBMedia & @Roche
Read more: mogproject.org/international…
We wonder if you can find your picture somewhere in the link 🤪
@Mayo_AING @EthelScl @LisaKRyan @mlevy18 @GabrielaRomanow @chenmayo @EoinFlanagan14 @ESotirchos @EliaSechi @darshi_r @FabienneBrilot @IzzyCotter & many more!
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The MOG Project retweeted
Exciting study showing that IGLON5 antibodies induce neurodegenerative signatures in vitro
science.org/doi/10.1126/scia…
This fits with the sequential human pathology in the same disease
academic.oup.com/brain/artic…
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The MOG Project retweeted
Great OCT study from @HopkinsMedicine @ESotirchos
Although AQP4 NMOSD causes worse optic neuritis outcomes than MOGAD, ganglion cell loss from retrograde degeneration seems similar, both greater than #MultipleSclerosis!
👀 So what drives worse vision in AQP4 NMOSD?
#NMOSD #MOGAD
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The MOG Project retweeted
May 18
Honored to be with the leaders who recognized #MOGAD as a distinct entity, young investigators paving the future, and patient advocacy groups making a difference! My 🩷🙌 Gabriela Romanow @mlevy18 @TheMOGProject for a conference as bright as the gorgeous day we shared in Boston!
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May 16
This weekend, we’re honored to convene leading international experts in #MOGAD research & care for the International Expert Panel on Research Directions in MOGAD in Cambridge, Massachusetts!
Together, global clinicians, researchers, advocates, & industry leaders will collaborate to help shape the future of #MOGAD research, treatment development, and patient care.
We’re especially excited for discussions focused on:
🔹 Worldwide disease patterns and diagnostic access
🔹 Mechanistic and biomarker research priorities
🔹 Future approved therapeutics for MOGAD
🔹 Quality of life, cognitive and behavioral health, and long-term outcome research
🔹 The patient experience and its critical role in shaping future research directions
A major goal of this meeting is to identify the field’s most urgent research gaps and future priorities — work that will help guide advocacy efforts, regulatory decision-making, and the development of a publishable consensus paper for a leading neurology journal.
We’re deeply grateful to the incredible experts and patient voices contributing to these conversations, and to our sponsors, including UCB Biopharma and Genentech, a member of the Roche Group, for supporting this important gathering.
We look forward to sharing more from the weekend ahead!
@FabienneBrilot @darshi_r @IzzyCotter @mlevy18 @MGHNeurology @ucb_news @Roche @Mayo_AING
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The MOG Project retweeted
A case report of Enteroviral encephalitis in a 37 year old woman taking kesimpta for multiple sclerosis. IgG was normal and IgM was low. MRI brain (image) shows symmetrical lesions in the thalamus. She improved but with ongoing neuropsychiatric symptoms journals.sagepub.com/doi/10.…
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The MOG Project retweeted
MOGAD frequently presents as cortical encephalitis and ADEM phenotypes with seizures and encephalopathy. Saini et al presented a case who presented with an extremely rare bilateral opercular syndrome phenotype (without seizures). #MOGAD @neuro_ian Link: 10.4103/aian.aian_1315_25
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The MOG Project retweeted
This proof-of-principle study demonstrates a rapid optofluidic approach to rapidly identify patient-derived monoclonal antibodies against conformational membrane antigens, such as those in #MOGAD: hubs.la/Q04fvWyk0
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The MOG Project retweeted
May 12
Reports of the clinician’s demise are greatly exaggerated! Happy to share this editorial, led by Dr. Buciuc, on study “MOG-IgG Positivity Does Not Equal MOGAD.” Antibody positivity and criteria are powerful tools but they do not replace clinical judgment👇thejcn.com/DOIx.php?id=10.39…
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The MOG Project retweeted
Maintenance Immunotherapy in MOGAD: Early Steroid Benefit, Dose Thresholds, and Disability Risk - Part 3 neurologyminute.libsyn.com/m…
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The MOG Project retweeted
Maintenance Immunotherapy in #MOGAD #NeurologyMinute @AANmember
neurologyminute.libsyn.com/m…
🎙️There is strong evidence that ≥12.5 mg/day (0.16 mg/kg/day paediatric) corticosteroids for 5 months from MOGAD onset reduces risk of relapse and permanent disability📉
#Neuroimmunology
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The MOG Project retweeted
Apr 23
A patient presents with reduced vision, color desaturation and pain on eye movements. What is your favored diagnosis?
View my Radiopaedia Case Read and get up to 0.25 AMA PRA Cat 1 Credits:
radiopaedia.org/courses/case…
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The MOG Project retweeted
Apr 25
Autoimmune encephalitis: what the radiologist needs to know link.springer.com/article/10…
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The MOG Project retweeted
#FLAMES, desafío diagnóstico. Fenotipo atípico de #MOGAD
1️⃣ Crisis epilépticas
2️⃣ Cefalea refractaria
3️⃣ Encefalopatía
Simulando un cuadro infeccioso agudo
RM: lesiones ⬆️intensas T2 cortical y unilateral
Confirmación por CBA
MTP precoz #Neuroinmunologia #NeurologiaClinica
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