Structural Biology. Immunology. Integrins. TGF-beta/BMP. Lab account for PI: @timothyspringer.

Joined December 2013
12 Photos and videos
Pinned Tweet
📣 The Springer Lab is hiring! Advance groundbreaking research at the intersection of integrin signaling, organoid development, and cell surface receptor mechanobiology. timothyspringer.org/news/202… #postdocjobs, #academictwitter, #ECRchat, #phdchat

3
3
574
Tim Springer Lab retweeted
Apr 8
Forbes will be co-hosting “America Innovates,” a free, open-to-the-public, family-friendly, three-day experience featuring an immersive walk-through exhibit, as a part of Forbes’ year-long campaign celebrating America’s 250th anniversary. Meet our speakers: forbes.com/sites/pr/2026/04/… #Forbes250
2
9
9
10,878
Tim Springer Lab retweeted
Feb 23
As the U.S. approaches its semiquincentennial, Forbes is focusing on what has always united the country: the American Dream and the innovation it inspires. That's why we're launching the Innovator 250, our list of the 250 greatest living American innovators, judged through Forbes’ entrepreneurial lens. #Forbes250 forbes.com/sites/randalllane… 📸: Jack Dorsey By Krishna Shenoi For Forbes, Judy Faulkner By Guerin Blask For Forbes, Vlad Tenev By Guerin Blask For Forbes, Oprah Winfrey By Krishna Shenoi For Forbes, Mark Zuckerberg By Guerin Blask For Forbes, Steven Spielberg By Chantal Anderson
9
16
40
10,498
Tim Springer Lab retweeted
Mar 19
Come experience innovations of the past, present and future as Forbes and @America250 cohost America Innovates on May 16-18 in San Francisco. The event is a free, open-to-the-public expo with business leaders in every industry and Forbes Innovator 250 honorees. eventbrite.com/e/america-inn… #Forbes250 #A250
3
5
18
13,467
We’ve joined Bluesky! Follow the Springer Lab (@springerlab.bsky.social) for insights into integrin and TGF-β signaling, mechanobiology, organoids and regenerative medicine, and structural biology. #Integrins #StructuralBiology #Biophysics #Organoids #RegenerativeMedicine
2
120
Thanks @ipiproteins for sharing our work!
From Viet Le & @timothyspringer of @timspringerlab @harvardmed @BostonChildrens: #Integrin αVβ6 has a specific & unappreciated role in #TGF-β2 activation, unlike the αVβ8-driven activation of TGF-β1/β3 & with big implications for fibrosis drug development pnas.org/doi/abs/10.1073/pna…
1
451
Tim Springer Lab retweeted
Hear a panel on synthetic #antibodies & #OpenScience 👇 🧪Errik Anderson, @AlloyTx 🧪@aledmedwards, @thesgconline & @UofT 🧪Andrew Kruse, @harvardmed 🧪Rob Meijers, IPI #Antibody Platform director 🧪Andreas Plückthun, @UZH_en 🧪Meghan Rego, @Addgene proteininnovation.org/ipisur…
2
2
1,201
Tim Springer Lab retweeted
Don't forget! Join IPI Surfacing tomorrow at @harvardmed. Networking, discussion, posters & talks👇 🧪Christopher Garcia, @Stanford 🧪Yvonne Jones, @UniofOxford 🧪@deboramarks, @Harvard 🧪Andreas Plückthun, @UZH_en 🧪Junichi Takagi, @osaka_univ_e proteininnovation.org/ipisur…
1
1
3
773
Tim Springer Lab retweeted
Proteins need to breathe: Stabilising conformations in a #malaria #parasite surface protein stops #Plasmodium #sporozoite migration and blocks transmission. Our latest collaboration with @TimSpringerLab out @emboreports. 'Fixing' TRAP 'kills' the parasite. doi.org/10.15252/embr.202357…
1
4
38
5,718
Tim Springer Lab retweeted
11 Jun 2023
Transforming growth factor (TGFß) is key regulator: immune system, development. There are 3 TGFß's; 1,2,3. Springer @BostonChildrens @HarvardMed use @ATUM_bio constructs. Show TGFß2 is activated by separate integrin. New opportunities for treating fibrosis pnas.org/doi/10.1073/pnas.23…
1
1
2
310
Tim Springer Lab retweeted
🎉 IPI has partnered with @Addgene to provide biomedical researchers worldwide with access to well-validated #antibodies and other reagents, and expertise on how to use them. Look out for our release of a set of #integrin antibodies this fall! Read more: proteininnovation.org/2023/0…
2
5
2,099
Tim Springer Lab retweeted
Recent research by @MyungHyunJO1 @taekjip @XuefengWang11 @timspringerlab & @ipiproteins shows exactly how #integrins harness chemical cues and respond to physical forces. Curious how it works? Read more here 👇 proteininnovation.org/2023/0…
2
7
2,405
Tim Springer Lab retweeted
With Richard Hynes & Erkki Ruoslahti, Springer discovered integrins, cell surface proteins that enable cells to interact with their surroundings Today, IPI is creating antibodies that can bind to integrins to accelerate #basicresearch and #drugdiscovery proteininnovation.org/2022/0…
4
6
Tim Springer Lab retweeted
Congratulations Richard O. Hynes, Erkki Ruoslahti, and Timothy A. Springer, 2022 #LaskerAward winners! — “for discoveries concerning the #integrins—key mediators of cell-matrix and cell-cell adhesion in physiology and disease”. @MIT @sbpdiscovery @harvardmed #Lasker2022
12
152
502