PhD candidate investigating protein phase separation and other small scale phenomena | @knowleslabcamb @Cambridge_Uni

Joined October 2020
9 Photos and videos
8 Feb 2023
Our paper on the digital sensing of protein:aptamer interactions is finally published! One platform shows the ability to sense everything from single proteins up to biomolecular condensates and exosomes, while elucidating many biophysical parameters. Congrats to all authors!
📢 Finally out now: Our paper describing DigitISA, a platform for direct digital sensing of protein biomarkers in solution 🧪 (incl. antibodies, amyloid aggregates & condensates). @KnowlesLabCamb @ChemCambridge Take a look: 👇nature.com/articles/s41467-0…
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Tim Welsh retweeted
A new method for determining the interaction strengths among compounds that form biomolecular condensates relies on measurements of just one solute in one phase. Read go.aps.org/3Guq7L6 @DaoyuanQian219 @TimWelsh_ @AbellJonny @GeorgKrainer @MichaelsLabETH @KnowlesLabCamb
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Tim Welsh retweeted
While antibodies have a remarkable track record in therapeutics, achieving sufficient specificity remains an issue. A Review in @NatRevChem discusses the physicochemistry of non-specificity and outlines future opportunities to improve protein binding. go.nature.com/3O8fK1y
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7 May 2022
En route to Heidelberg for the #EESPhaseSeparation conference. Only a few more countries to cross before Monday morning! Come find me all week if you want to chat condensates, microfluidics, or bikes!
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25 Feb 2022
When theorists and experimentals collaborate good things happen @DaoyuanQian219. Excited to share our work on the measurement and mechanistic insights of tie-lines in biomolecular phase diagrams. Also, maybe we should stop calling PEG an "inert crowder"? biorxiv.org/content/10.1101/…
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Tim Welsh retweeted
More from @KnowlesLab at #bps2022 in #SanFrancisco. @eaandrzejewska @mus_greta, Alyssa & @TimWelsh_ presenting posters on pre-fibrilliar protein #aggregates and single-molecules studies, oligomer-membrane interactions, microfluidic spray-deposition & #biomolecular condensates.
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19 Jul 2021
Pretty stoked to finish 4th overall (3rd male) in the British 24hr Cycling Time Trial National Championships Easily met my main goal of breaking the 55 year old Cambridge University record Taking a day to recover before training loads of new students on microfluidics this week!
Updated provisional overall result. Please let us know if any further issues.
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29 May 2021
Final #transengland21 activity. @theracingcoll Will be back for more in the future and try to have less mechanicals... strava.app.link/CdvlUQUOEgb
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29 May 2021
Finish 15:54. Brutal #transengland21
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29 May 2021
CP5 robin hood's bay #transengland21
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29 May 2021
CP4 - St Nicholas church #transengland21
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29 May 2021
CP3 highest Inn in Britain #transengland21
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29 May 2021
CP2 after some brutal gravel #transengland21