Excited to share our latest work, creating an artificial lipid droplet! 🦠🧠
This is @TimetogoZ's first first-author paper from her PhD, and my first senior-author paper!! 🎉🥹
Check it out ⬇️
sciencedirect.com/science/ar…
And #COVID can also damage the vision by crossing the blood-retinal barrier after systemic exposure. And don't forget the retina is part of the brain. #NeuroCovid
More here: medicine.missouri.edu/news/c…
SARS-CoV-2 induces Alzheimer’s disease–related amyloid-β pathology in ex vivo human retinal explants and retinal organoids | Science Advances science.org/doi/10.1126/scia…
Virtual staining offers a promising approach to map dynamic cellular systems across various cell types conditions, broadening the scope of live-cell imaging. Congrats to Shalin Mehta & the team at #CZBiohubSF 🎉🙌 bit.ly/4jZJCvg
A little bit late but as they say, better late than never!
Introducing the✨2025 MAPP HDR Executive Committee✨
Stay tuned for a bunch of fun upcoming events planned for the year, with trivia and our monthly Active Hour already in the books!
1/2 🧪 Iodine is a critical ingredient in the chemical industry as a reagent which converts stable Carbon-Hydrogen (C-H) bonds into unstable and reactive Carbon-Iodine (C-I) bonds – prized for their ability to help change and create new molecules. Read: pubs.acs.org/doi/full/10.102…
📢 Exciting new research from @SABE_latrobe opens new doors for future biomedical research!
Dr Zahra Telikani from @HelbigLab has developed tiny fat-based particles that travel to a wider range of cells and organs (including the brain) in mice and zebrafish models.
Read more 👉 shorturl.at/UYWep “
The current attack of the US government is devastating. The internationals in my lab are asking can I come to work today ? I told them NO because I’m afraid government officials will come to arrest them - those are LEGAL international scientists that just lost their visas due to government attacks on Harvard. This is UNPRECEDENTED in the history of United States. Some of these internationals are Jews . This is NOT an antisemitic attack this is ATTACK ON SCIENCE.
Published today in Nature, @CamiloFaustAkl et al. (@KeithLigon5, @EAChiocca , @QuintanaLabHMS) reveal that GBM co-opts TRAIL astrocytes to suppress anti-tumor immunity.
The team identify a distinct subset of TRAIL astrocytes within the GBM tumor microenvironment that induces apoptosis in CD4⁺ and CD8⁺ T cells via a GBM-secreted IL-11 -> STAT3 signaling axis. These astrocytes also modulate microglia- and monocyte-derived TAMs, further amplifying T cell dysfunction. Notably, high TRAIL and IL-11 expression correlated with faster recurrence and worse survival in GBM patients, underscoring the clinical relevance of this pathway.
Crucially, this immunosuppressive circuit can be therapeutically disrupted using an oHSV engineered to express an anti-TRAIL scFv—providing a compelling proof-of-concept for precision immunovirotherapy in GBM.
@MGBResearchNews@MassGenBrigham, @harvardmed@bcmhouston@BUMedicine@DanaFarber@broadinstitute@mcgillu
👏 Not only fantastic cross-disciplinary research from across LIMS & @SABE_latrobe, but a special milestone of firsts for @HelbigLab members Zahra Telikani (first-time first author) and Dr Ebony Monson (first-time senior author). Congrats to all!
Read 👉 sciencedirect.com/science/ar…
So that’s just some of the research we do here at our multidisciplinary research centre! But
today, we are joining together for a Healthy
Heart Walk, and together, choosing healthier
lifestyle choice & luckily surrounded by @latrobe’s beautiful scenery! 🍂🍃#HeartWeek2025
I've had so much fun organising the LIMS Discovery tours this year!! If you don't have plans on Sunday, come along and check out our wonderful labs at @LIMSLTU!!
1/2 🦠 It’s the International Day of Immunology – and we would like to acknowledge our fantastic scientists in LIMS’s Infection and Immunity Program whose research investigates how to harness the immune system to better fight disease.