PhD candidate in Neuroscience, McGill University. #HBHL#DKG#FRQS fellowship recipient. Studying #epigenetics in the human brain at single-cell resolution.
In this paper, we explored the functional role of the genome-wide significant DNA locus on chromosome 7 linked to FOXP2 gene and associated with suicide risk and attempts using genotypes and single-cell data.
nature.com/articles/s41380-0…
Curious about how brain cells are different in people with major depressive disorder (MDD) who died by suicide? We uncovered genetic variation in NR4A2 neurons and disruption in microglial function. Join me on Monday, Oct 7th (Poster M35, 8AM-12PM) #sfn2024#sfn24🧠✨See you! :)
What are the long-term impacts of trauma? How can it cause depression? How can we try to answer these questions through DNA sequencing of brain cells? Please join me for my talk on May 8th @HBHLMcGillhbhlsymposium.ca/speakers/ Register: eventbrite.ca/e/hbhl-symposi…
Differential Chromatin Architecture and Risk Variants in Deep Layer Excitatory Neurons and Grey Matter Microglia Contribute to Major ... biorxiv.org/cgi/content/shor…#biorxiv_genomic
I am very proud of this work in collaboration with Gustavo Turecki, driven by the brilliant @MalosreeM and supported by @TrippyNeuron, Naguib Mechawar and many others @DouglasResearch
🔥Hot off the press @NatureComms: @DrCorinaNagy et al. show concordant cortical transcriptomic patterns in #depression within individual cell types in males and females, although major dysregulated cell types and genes were distinct for each sex.♂️♀️ 👇
nature.com/articles/s41467-0…
Anjali Chawla sharing the aims of her study on "Cell-type specific open #chromatin signatures in the brains of individuals diagnosed with major depressive disorder and died by suicide."
#CanEpi21#ThisIsEpigenetics
Tune-in for my talk on Nov. 5th at the 7th Annual Canadian Conference on Epigenetics. The talk will be directly related to my PhD research on - "Cell-type specific open chromatin in the brains of individuals diagnosed with the major depressive disorder"
x.com/CEEHRC/status/14229580…
Registration is OPEN! The 7th Canadian Conference on Epigenetics is November 2 to 5, 2021 with both in-person (at Estérel, Quebec) & virtual attendance options. Visit ceehrc.ca/2021 for confirmed speakers & info on registration, travel awards & abstract submission
This article reviews the #chromatin research in disease occurrences, elucidating how non-coding genetic variations impact complex diseases. Congratulations to the authors!
More info: mdpi.com/1422-0067/22/14/761…