Pediatric oncologist and Physician-Scientist at MSKCC. Receptor tyrosine kinase (RTK) fusions and condensates in cancer. DNA repair. Pediatric sarcomas.
Beyond thrilled to share that I am moving to Memorial Sloan Kettering this fall to join #MSKKids, the Tow Center for Developmental Oncology and HOPP. The @TulpuleLab will be hiring at all levels! Can't wait to get to work. See you soon, NYC! @MSKCancerCenter
It can be hard to say no to service requests in academia.
We sought advice on how to ensure researchers don’t get stuck doing unpaid labour
go.nature.com/4bUX6WN
The Tulpule Lab is looking for research technicians. Come spend a few years in New York City and help advance pediatric cancer research!
Research Technician in NYC @TulpuleLab
Memorial Sloan Kettering Cancer Center
See the full job description on jobR...
jobrxiv.org/job/memorial-slo…
Postdoctoral Fellow - Cancer Research at MSKCC @TulpuleLab
The Tulpule lab at MSKCC is seeking postdocs to study pediatric cancer, biomolecular condensates, and DNA repair.
To read the full job description and apply, see link in the thread!
#cancer_biology#cell_signaling #...
We posted a BIG update to our study on Ewing sarcoma and other FET fusion-driven cancers. FET fusion oncoproteins are aberrantly recruited to DNA breaks and cause ATM defects, which can be targeted with the ATR inhibitor elimusertib. Updates include:
biorxiv.org/content/10.1101/…
We would love to hear feedback, opportunities for new directions and collaborations. This is the work of many at @UCSF and @MSKCancerCenter, but led by 2 super star postdocs @Shruti_menon09 and @DmGracilla33811.
2. New mechanistic studies of the interaction/competition between EWSR1-FLI1 (the Ewing fusion) interaction with native FET proteins (i.e., EWSR1) at DNA double-strand breaks.
3. Cell-line and PDX testing of the ATR inhibitor elimusertib as a synthetic lethal therapeutic strategy to target ATM defects across the class of FET rearranged tumors.
Meet #MSKPostdoc Daniel Gracilla from the @TulpuleLab. Daniel is studying the role of FET and FET fusion proteins in altering DNA 🧬 damage response to elucidate the DNA Damage Repair vulnerability of Pediatric Sarcoma.
🇵🇭 #NPAW2024#MSKKids
ALT #BestPartOfScience: Using our imagination to further expand the explanation of biological and other scientific phenomena and unveil the secrets of nature.
#CareerMotivation: To all hard-working postdocs out there, we need to keep going. Who knows, one of us may be on the verge of making another groundbreaking cancer treatment. Despite the challenges, we need to forge ahead.
#BecomingAScientist: I wanted to blaze a new trail in which I can contribute to ensuring the health of the world. Back in grade school, I had been fascinated with biological things like how our heart beats, how our eyes can see, how a bird can fly, and even how a fish can swim. That propelled me to pursue a scientific career.
Daniel Gracilla, PhD
Tulpule Lab
33 fully funded PhD positions are available this autumn for people interested in studying the devastating childhood tumor neuroblastoma in Berlin (Charité, MDC), Heidelberg (DKFZ) or Cologne. Please share with your students.
nature.com/naturecareers/job…