With decades of experience in the synthesis & application of Voltage Sensitive Dyes, we can help you choose and use the best VSDs for your experiment or assay.
Joined July 2019
- Tweets 18
- Following 15
- Followers 23
- Likes 12
6 Photos and videos
Just out, led by collaborator Leonardo Sacconi. Uses di-4-ANBDQPQ (Cytovolt2) to combine electrophys, 3D morphometry and modeling.
nature.com/articles/s44161-0…
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8 Apr 2025
Explore unprecedented depths in cardiac voltage imaging! Our patent-pending chromene-based dyes are excited at 730nm, unlocking novel applications.
Our ElectroFluor730p™ has been tested by our collaborators at lens.unifi.it/
Visit PotentiometricProbes.com for more info
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Potentiometric Probes retweeted
11 Feb 2024
Visit Cytocybernetics at booth 634 at @BiophysicalSoc to see plug and play dynamic clamp, voltage-sensitive dyes, and CiPA software #BPS2024
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2 Feb 2024
And come to poster B477 on Tuesday 2/13 to learn about our new series of near ir VSDs excitable at 730nm
Looking forward to seeing all my @BiophysicalSoc friends at #bps2024 in just a week.
biophysics.org/2024meeting#/
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30 Nov 2023
UConn Startup Earns Small Business Grant to Commercialize Voltage-Sensitive Dyes today.uconn.edu/2023/11/ucon…
Potentiometric Probes Awarded $1.9M NIH Phase II SBIR
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Potentiometric Probes retweeted
13 Nov 2023
Visit poster C3 at the neuroscience meeting, then come visit us at Booth 938!!! #DynamicClamp #electrophysiology #SfN2023 #SfN23
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9 Nov 2023
Ratiometric dual wavelength voltage imaging of beating pig heart in vivo. Using one of our ElectroFluor VSDs. in the latest issue of @BiophysJ
cell.com/biophysj/fulltext/S…
youtube.com/watch?v=muRPXoWV…
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And here's the movie (@VSDexperts)
In vivo ratiometric optical electrophysiology in live pig heart
authors.elsevier.com/c/1hvgi…
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Potentiometric Probes retweeted
12 Oct 2023
Excitement for the @43North_ FINALS tonight is growing as we attend the 43Northe showcase!
Good Luck to all Finalists!
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Very detailed theoretical chemistry study of a classic VSD in a lipid membrane with an applied voltage.
Simulating the Voltage-Dependent Fluorescence of Di-8-ANEPPS in a Lipid Membrane | The Journal of Physical Chemistry Letters pubs.acs.org/doi/10.1021/acs…
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Our near IR VSD paper is out, introducing ElectroFluor730 (& more); thanks to the heroic organic synthesis by Ping Yan, with talented @UConnOUR undergrads Giuliana Judge & Alexa Monroe; great cardiac imaging by @LeonardoSacconi & Vale Biasci. @VSDexperts
pnas.org/doi/10.1073/pnas.23…
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Here is a scientific obituary written by Larry's friends and family @BiophysicalSoc @SfNtweets
So sad to report the passing of Larry Cohen. My friend and collaborator of over 40 years. The pioneer of optical voltage sensing and a giant in neuroscience. Wearing a red shirt and telling chicken jokes...
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21 Feb 2023
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13 Oct 2022
Website significantly enhanced with many useful tips, data and new VSDs. Also finally started using easy names for our popular fluorinated dye series: no more need to remember "di-4-ANEQ(F)PTEA", now it's "ElectroFluor630" potentiometricprobes.com
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11 Nov 2020
Advantages of ratiometric voltage imaging of spontaneously beating, human stem cell-derived cardiomyocytes (iPSC-CMs provided by Anthony Pettinato and @TravisHinson) using Di-4-ANEQ(F)PTEA (potentiometricprobes.com/di-…).
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14 Jan 2020
Optical electrophysiology in vivo pig model. Ratio imaging solves the motion problem during beats. New fluorinated long wavelength VSD facilitates loading and has low toxicity. Large animal model is a key step toward human imaging. academic.oup.com/cardiovascr…
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