A hub for Extracellular Vesicle Enthusiasts around the globe. #exosomes #extracellularvesicles #disease #therapy #biomarker #technology.

Joined March 2020
435 Photos and videos
New Research: Small extracellular vesicles derived from four dimensional-culture of mesenchymal stem cells induce alternatively activated macrophages by upregulating IGFBP2/EGFR to attenuate inflammation in the spinal cord injury… frontiersin.org/articles/10.… #bioengineering #biotech
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Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall biorxiv.org/cgi/content/shor… #bioRxiv

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Similar but distinct: the impact of biomechanical forces and culture age on the production, cargo loading, and biological efficacy of human megakaryocytic extracellular vesicles for applications in cell and gene therapies biorxiv.org/cgi/content/shor… #bioRxiv

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Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma? | Bruno Sarmento @i3S_UPorto | @brunocsarmento @CRS_SPLC #cancervaccine #genetherapy #exosome #tumormicroenvironment doi.org/10.1016/j.jconrel.20…

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New Research: Bacterial extracellular vesicles and associated functional proteins in fermented dairy products with… #microbiology frontiersin.org/articles/10.…

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iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles biorxiv.org/cgi/content/shor… #bioRxiv

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Exosomal microRNA signature from plasma-derived extracellular vesicles in gastric cancer biorxiv.org/cgi/content/shor… #bioRxiv

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Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery biorxiv.org/cgi/content/shor… #bioRxiv

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Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma? | Bruno Sarmento @i3S_UPorto | @brunocsarmento @CRS_SPLC [50 days' free access] #exosome #glioblastoma authors.elsevier.com/sd/arti…
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High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy biorxiv.org/cgi/content/shor… #bioRxiv

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Solid tumor EV cluster bombs inhibit CAR T cells - small extracellular vesicles carry tumor antigens & immune checkpoint PD-L1, preferentially interact w cognate CAR T cells inhibiting proliferation, migration, & function aacrjournals.org/cancerres/a…
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Sox9 Regulates Extracellular Matrix Stiffness during Vascular Smooth Muscle Cell ageing by increased secretion of LH3 via extracellular vesicles. biorxiv.org/cgi/content/shor… #bioRxiv

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New Research: Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability: Introduction Extracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers… #immunology frontiersin.org/articles/10.…

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#PeerReview from @eLife of 👉🏿 Improved Isolation of Extracellular Vesicles by Removal of Both Free Proteins and Lipoproteins biorxiv.org/content/10.1101/… #bioRxiv #reviewedpreprint

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A rapid one-pot isothermal assay that leverages rolling-circle amplification and the endonuclease Cas12a can accurately detect specific miRNAs in extracellular vesicles in patient plasma. rdcu.be/da7IE
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