Please consider giving your pathology images a forever home on WebPathology. Now you can load them directly from the site using Submit Images form. Give it a try. Webpathology.com: A Collection of Surgical Pathology Images #PathTwitter #PathX

I refrain from posting anything non-pathology related on this account....however, I couldn't resist sharing this with you. If you are ever in Richmond, Virginia, pay them a visit...their single malts and old-fashioned are to die for.....

Update in #HemePath - Intranodal Palisaded Myofibroblastoma; 15 images; check it out on the website under Hematopathology ➡️Lymph Node➡️Spindle & Vascular Proliferations #pathresidents #pathology

Update in #HemePath - Progressively transformed germinal centers. 20 images. Check it out on the website under Lymphadenopathies - II.

Rosai-Dorfman disease in skin -somebody please call the police - the emperipolice! An S100 protein stain highlights the nuclei (arrow) and cytoplasm of abnormal histiocytes but not the engulfed inflammatory cells in the cytoplasm (emperipolesis - engulfment without destruction).

I’m updating mediastinum section and looking for images of T-cell lymphoblastic leukemia/lymphoma. Anyone have a case that they would like to contribute? Thanks. #hemepath

Macroscopic examination of a prostate specimen, with a focus of malignancy at the extreme superior, dark yellow in color. Necropsy finding

50s M, bladder transurethral resection. Diagnosis? #PathTwitter @MGBpathology @MGHPathology

Public service announcement of the day: remember that ALK alterations are not only seen in lung adenocarcinomas. Here is an example of a carcinoid tumor with ALK fusion (extremely rare, except here at #Moffitt). We are certainly writing this one up. The IHC is ALK D5F3. Pulmonary carcinoid tumors very rarely harbor ALK rearrangements, in contrast to non–small cell lung cancers where ALK fusions represent a well‑established oncogenic driver. The literature documents only isolated case reports, underscoring the exceptional nature of this finding. This scarcity suggests that ALK testing in carcinoid tumors is generally low yield; however, when detected, these fusions may offer meaningful therapeutic implications, particularly given the success of ALK inhibitors in other thoracic malignancies. #lung #pathology #pulmpath #thoracicpath #MedEd #PathTwitter

This metastatic leiomyosarcoma reached the colonic mucosa.

Pseudomyxoma peritonei, in the form of a high-grade mucinous peritoneal neoplasia with signet ring cells (G3). History of appendiceal mucinous neoplasm. CDX2 and Alcian Blue are shown here. #PathX #pathresidents #PathTwitter

Additional images: Lymphoepithelioma-like Urothelial Carcinoma. Sheets, clusters of undiff. cells with syncytial appearance surrounded by lymphoplasmacytic infiltrate. Resembles nasopharyngeal lymphoepithelioma but lacks association with EBV or HPV. Pos for cytokeratins, GATA3.

Bladder mass in an elderly male. What is your diagnosis? Additional images to follow. #gupath

Here's the entire case with additional images. Adult male. Large ulcerated, indurated lesion on foreskin. T. pallidum antibody test reactive. Organisms readily seen with T. pallidum immunostain. Final Diagnosis: Primary #Syphilis #gupath

Adult male with a large ulcerated and indurated lesion on foreskin. What would you do next? Additional images and diagnosis will be posted later. #gupath

Can you identify the organ/site and the diagnosis?

Collagenous micronodules in #ProstateCancer. A specific but infrequent finding, usually in mucin-producing CaP. Not seen with benign prostate, nodular hyperpl or high-grade PIN. #GUPath