Computational Cancer Genomics Lab - Turn Cancer Data into Knowledge
Joined March 2021
- Tweets 43
- Following 156
- Followers 128
- Likes 158
1 Photos and videos
19 Sep 2025
๐ New preprint! scXpand โ the first ML framework to detect T-cell clonal expansion from scRNA-seq (no TCR needed). Built on 2.6M T cells, robust across cancers & TME contexts.
๐ Led by Ofir Shorer & @RonAmit5
๐ doi.org/10.1101/2025.09.14.6โฆ
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19 Sep 2025
๐ป Code: github.com/yizhak-lab-ccg/scโฆ
๐ Docs: scxpand.readthedocs.io
#MachineLearning #scRNAseq #scTCRseq #CancerResearch #Bioinformatics #bioRxiv
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6 Apr 2025
๐ข Excited to share our new paper in @CellGenomics!
We analyzed matched #scRNAseq and #scTCRseq from 767K T cells to uncover clonal programs that predict response to immune checkpoint inhibitors.
๐ cell.com/cell-genomics/fulltโฆ
#CancerImmunotherapy
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2 Apr 2025
๐ข Excited to share our new paper in #npjPrecisionOncology: We present a roadmap for using #scRNAseq and #MachineLearning to study and predict response to immune checkpoint inhibitors.
๐ nature.com/articles/s41698-0โฆ #CancerImmunotherapy
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KerenYizhakLab retweeted
17 Mar 2025
ืืืืื ืื ืืชืื/ื ืืืื ืืคืชืื
ืืืกืืื ืืืืฉ ืืชืืืจ ืฉื ื ืขื ืืชืืืืช ืืจืคืืื ืืืฉืืืืช
ืืคืงืืืื ืืจืคืืื ืืืื ืืื!
20.3, ืืฉืขื 16:00 .
ืืคืจืืื ื ืืกืคืื :
compmed.net.technion.ac.il
ืืืจืฉืื ืืืื ืืคืชืื:
did.li/n8e6q
ื ืชืจืื!
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3 Oct 2024
๐จ New preprint alert! We performed scRNA-seq & scTCR meta-analysis on cancer patients treated with ICIs, revealing key T cell signatures linked to therapeutic response, with insights into clonal replacement vs reinvigoration! #scRNAseq #Immunotherapy
biorxiv.org/content/10.1101/โฆ
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KerenYizhakLab retweeted
20 Sep 2024
We are excited to share the agenda for our 1st annual event, 26/9 @ELSCbrain๐ช
w/ spotlights ๐ฆ@YOrenLab, Amos Tanay, @yizhaklab, @atownfool & @SItzkovitz.
A field overview by @mor_nitzan & @naomi_habib, and sc-ience sessions led by @bitonm, Oren Ram, @YosefLab & @OCohenlab
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KerenYizhakLab retweeted
10 Jun 2024
Iโm happy to share our new paper showing moonlighting function of ASS1 in the nucleus. Under the tough circumstances we are facing this paper would have never been published without the help of a wonderful editor, great collaborators and resilient students. Thank you all! โฅ๏ธ
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KerenYizhakLab retweeted
5 Feb 2024
We celebrate the much-deserved selection of @gaddyg to this yearโs class of 2024 AACR Academy Fellows!! Congrats, Gaddy ๐! aacr.org/about-the-aacr/newsโฆ
@MGHCancerCenter @broadinstitute
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My second cousin Yagev Buchshtab was kidnapped on October 7 and is being held in Gaza for 81 days now. Please listen to his sister Nufar and share.
26 Dec 2023
My brilliant PhD student Nufar, whose brother is a hostage in Gaza for over 80 days. Nothing prepared me to being a mentor under such a scenario. How can we even continue research in the lab?? Please help her, help us, spread this heart-breaking humanitarian call.
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We are thrilled to announce that OncoHost has been named one of the Top 10 Precision Oncology Solutions Companies of 2023 by @HealthCareTO! ๐
Thank you for this honor ๐
Read more: bit.ly/4a4BjdT
#PrecisionOncology #HealthcareInnovation #CancerResearch #Proteomics
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KerenYizhakLab retweeted
5 Dec 2023
Happy to share this work lead by Daniel Schaffer, using a deep learning model to identify microbial RNAseq reads that are assembled into longer contigs. We find that the presence of several microbial genes strongly predicts outcomes in esophageal cancer
nature.com/articles/s43705-0โฆ
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KerenYizhakLab retweeted
ื ืขื ืื, ืืืฉืคืืชื ืฉื ืกืืจ ืืืจื ืงืืืจืื ืฉืฉืืืจืจื ืื ืืืืื ืขืืคืจ ืขืืืื ืืืืฃ, ืืืืื ืืชืืื ืืช ืืืืคื ืืืฉืืช 12.
ืื ื ืฉืื ืงืืข ืืืืจืื, ืขื ืืชืืืืืช.
ืืฆืคืืช, ืืืคืืฅ ืืื ืขืืจ
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27 Oct 2023
In these darkest days our country have ever known, we somehow manage to do science. Our new paper shows how #metabolism of immune cells predicts patients response to ICI. Ofir finished this paper while in reserve duty helping to bring our people back home
cell.com/iscience/fulltext/Sโฆ
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KerenYizhakLab retweeted
20 Oct 2023
ืืกืจื ืืื ืืื ืืืื ืืืจืืืช - ืืื ืคื ืืืืจืื ืืืขืืขืื ืืจืืืฉืื - ืื ืกื ืืืงืฉืื ืืืจืืืช ืฉืืืื ื ืจืฆื, ืืื ื ืืืคื ืืืืื ื ืขืืจ
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KerenYizhakLab retweeted
19 Oct 2023
An Open Letter to Every Parent In America
Please help me get this message out to every parent in the United States.
Please help me protect your children.
I am BEGGING you - "liking" this is not enough.
Please retweet right NOW.
youtube.com/watch?v=uo7fdxrjโฆ
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KerenYizhakLab retweeted
21 Sep 2023
Before we have to pay to tweet, I want to post an opening for a PhD position at the Weizmann Institute for a student interested in characterizing the tumor MACROenvironment for therapeutic implications.
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22 Apr 2023
Check out our new #preprint on the metabolism of immune cells in the TME of patients treated with #immunotherapy led by Ofir Shorer. We analyzed scRNA-seq from >1M cells and found a metabolic signature predictive of response across cancer types. biorxiv.org/content/10.1101/โฆ
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23 Feb 2023
We had a great time at the #ILANIT2023 meeting. Very proud of my team with 4 talks, 3 posters, 3 runners and one fun lab outing which as usual, we forgot to take a photo of.
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KerenYizhakLab retweeted
11 Jan 2023
Our work on genomic compartments is now out in @NAR_Open!
I really have to commend both the reviewers and NAR team for very professional and speedy handling of the manuscript ๐๐๐
academic.oup.com/nar/advanceโฆ
5 Oct 2022
New preprint!
biorxiv.org/content/10.1101/โฆ
So whatโs the deal with this checkered Hi-C pattern, aka genomic compartments (GC)?
Led by the one and only Hagai Kariti @hakariti
Tweetorial>>
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