Account managed by members of Ziv Reich's lab at the Weizmann Institute

Joined August 2022
5 Photos and videos
Ziv Reich's lab retweeted
This study was conducted by Maor Knafo, Elena Casacuberta, and Iñaki Ruiz-Trillo at @IBE_Barcelona.
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Ziv Reich's lab retweeted
By modeling individual organisms as learners that are capable of building, refining, and testing internal models of environmental states, this study offers a new paradigm for understanding biological adaptation beyond passive selection. Check it out: go.aps.org/4vAU56R
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Ziv Reich's lab retweeted
17 Feb 2025
With a DNA barcoding method called gUMI-BEAR, scientists show how yeast populations adapt to environmental stressors through two distinct modes depending on stress type — rare or prevalent — indicated by their gene expression variability. Read the paper: go.aps.org/40W3OrX
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Ziv Reich's lab retweeted
31 Jan 2025
We (finally) managed to publish the first part of my PhD! In many ways, this work challenged most of the fundamental stuff I think about how yeast adapt to stress, the roles and mechanisms of inducing variability, and how we should even approach approximating it.
30 Jan 2025
Yeast populations adapt to environmental changes through two distinct modes that depend on stress familiarity: Rare stressors trigger uniform adaptation while familiar ones elicit diverse responses, reflected in gene expression variability. 🔗 go.aps.org/40W3OrX
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Ziv Reich's lab retweeted
17 Jan 2024
Here, the authors describe CosMIC as a hybrid approach for large-scale, high-resolution microbial profiling of novel niches. This powerful tool for profiling microbial diversity detected over 40,000 novel small subunits. bit.ly/3RFSw6o #PoweredByPacBio
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Ziv Reich's lab retweeted
10 Dec 2023
A new #preprint! Variability is strange, right? Especially when it arises in the background of an identical genetic background. Why would cells, having the same machinery, regulation, and environment, behave differently? Why would there be #noise? 1/13 rb.gy/45y36m
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Ziv Reich's lab retweeted
4 Sep 2023
🚨 New preprint alert! 🚨 biorxiv.org/content/10.1101/… Is microbiome surveying accurate? Meaningful? Robust? For the most part, the answer is sadly underwhelming, especially for those working in undersampled niches. 1/8
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Ziv Reich's lab retweeted
8 Jun 2023
🎉New publication alert!🎉 (First yeast one!!🍞🍺) Ever wondered what your life could have been if you'd made different choices? How much of you is determined by your genes? For yeast cells, we have answers! [1/9] journals.plos.org/plosone/ar…
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Happy to share our first microbial evolution preprint describing gUMI-BEAR, a modular, cellular-barcoding method that can be used for large-scale, unsupervised variant screening and to repeatedly track the evolution of the same populations. biorxiv.org/content/10.1101/… 🧵1/1
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Applying the gUMI-BEAR method to track the evolutionary dynamics of 26,000 lineages for 44 days while the population undergoes several temperature changes. 🧵5/6
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Applying gUMI-BEAR for a large-scale, unsupervised screen of variants containing 2-4 randomly generated mutations in the Hsp82 gene. Using the barcode as a reverse primer, we could isolate variants that made up less than 0.2% of the population for further study. 🧵6/6