We study single-cell genomics, cancer heterogeneity, aging, complex diseases, and anything else that satisfy our curiosity.
Joined June 2018
- Tweets 38
- Following 83
- Followers 86
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The first AI-based study from my lab. I am actively learning how to use attention matrices in research, and more is to come. A big shout-out to the fabulous Yang Zhang from my lab.
biorxiv.org/content/10.64898…
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Read our latest rdcu.be/dNPbB on a new single-step Single-Cell Total-RNA-seq method: SnapTotal-seq and its applications in identifying regulatory hubs of TFs, published with @SpringerNature in @NatureComms. So proud of two fabulous students: Yichi Niu & Jiayi Luo.
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What we may be able to do in a few years if funded...
nature.com/articles/s41386-0…
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Zong Lab retweeted
4 Aug 2023
Ever since our discovery of multi-receptor expression in the developing nose in 2015 @MolSystBiol and solving their 3D genome structure in 2019 @NatureSMB, it has been my dream to measure them (RNA Hi-C) from the same cell. We finally did it! Thank you @Wu_Honggui for hard work
4 Aug 2023
I'm thrilled to introduce our latest technique—LiMCA (Linking mRNA to Chromatin Architecture (LiMCA)), from Sunney's lab @XieSunney, which simultaneously profiles 3D genome and transcriptome with the same cell. Preprint: researchsquare.com/article/r…
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Zong Lab retweeted
14 May 2023
Most of academia is by now so distracted by grantsmanship, publishing, and administration they no longer even seen it as a distraction.
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Zong Lab retweeted
Congratulations to Dr. Gibbs @BCM_HGSC, Dr. Doddapeneni, Dr. Rui Chen, Dr. Sedlazeck @sedlazeck and Dr. Zong @Zonglab on your funding to study somatic mosaicism and its full impact on human health!
11 May 2023
Read more about Dr. Chuck Zong's #SomaticMosaicism project @bcmgenetics to detect somatic mutations in single cells for wide use within the #SMaHTnetwork bcm.edu/news/baylor-college-…
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Zong Lab retweeted
As a medical #geneticist, Dr. Brendan Lee helps #patients understand their #geneticInformation so they can use it to make decisions about their #health, #diet, and #wellbeing. @AllofUsResearch @bcmgenetics @BCM_MSTP @BCMDeptMedicine @bcmhouston allofus.nih.gov/news-events/…
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Our paper on high-throughput transcriptome profiling of individual synapses is online. Congratulations to all the students and postdocs contributing to this work. Cannot express enough gratitude to Dr. David Weitz and Dr. Hui Zheng for their gracious support throughout this work.
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Single-cell Damagenome Profiling by Linear Copying and Splitting based Whole Genome Amplification (LCS-WGA) —BIO-PROTOCOL en.bio-protocol.org/e4357#.Y…
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DNA 'Damagenome' May Provide Disease Clues, Study Suggests genomeweb.com/sequencing/dna…
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Very proud of my team, special thanks to the two co-first authors: Qiangyuan (now with his own lab at Zhejiang U) and Yichi. This work will have far-reaching impacts on human disease. You can count on my words. advances.sciencemag.org/cont…
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doi.org/10.7554/eLife.64204 @eLife
The first mouse model work from my lab. It combines transcriptome profiling of individual early neoplastic lesions and SWI/SNF complex related mechanistic study in pancreatic cancer. Congrats to all who contributed to the work.
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Please retweet! Check out jobrxiv.org, the job board for scientists, by scientists: Thousands of jobs from academia and industry, free job postings and candidates from over 160 countries @jobRxiv
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cell.com/cell-reports/fullte…
Another good example of MATQ-seq in detecting subtle heterogeneity among the apparently homogeneous cells.
Kudos to Neus, Priyam, Yichi, and Wenjian for deliverying it.
Zong Lab retweeted
18 May 2020
New Article online now at Cell: Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients’ B cells zpr.io/tvueJ
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Nobel winner who transformed condensed-matter and particle physics. ift.tt/35mNf9X
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Zong Lab retweeted
5 Feb 2020
I am delighted that today we are announcing that newly submitted papers to @nature will be published with peer review reports & authors' rebuttals upon their acceptance #peerreview #transparentreview nature.com/articles/d41586-0…
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Zong Lab retweeted
22 Nov 2019
Thank you @sciencemagazine for this award! I'm extremely honored to be selected.
21 Nov 2019
Longzhi Tan has been named the 2019 Grand Prize winner of the Science & @SciLifeLabPrize for Young Scientists for his work in developing an approach that allows us to visualize our genome’s three-dimensional structure. fcld.ly/tkjhvo6
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Zong Lab retweeted
28 Mar 2019
Super-resolution imaging of transcripts from 10,000 genes in single cells—a >10-fold improvement over current methods #NBThighlight go.nature.com/2U2B4N7
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