Official Twitter of the Journal of Cerebral Blood Flow & Metabolism @_JCBFM is the Official journal of #ISCBFM (iscbfm.org) & biannual meeting #BRAIN2025
📢 Call for up to 2 co-chairs for the Education Committee of the ISCBFM!
Help shape key Society & Brain Conference programs, including Small Meeting Sponsorships, Lab Travel Bursaries, Education Day, and Satellite Symposia.
Interested? Apply here: iscbfm.memberclicks.net/inde…
🚨 What if aging and obesity were silently shrinking the brain’s backup blood supply?
New #HotTopic reveals aging dramatically impairs collateral artery growth after stroke ,far more than obesity, crippling blood flow recovery.
🔗 Free access (1 month): doi.org/10.1177/0271678X2514…
🚨 Could a single gene mutation turn brain vessels into time bombs?
#HotTopic shows KRASG12V mutation in endothelial cells triggers bAVM, and also inflammation, BBB breakdown destabilizing vessels.
🔗 Open access: doi.org/10.1177/0271678X2614…
Excited to share our latest publication in @_JCBFM demonstrating that targeting cellular senescence mitigates the effects of midlife obesity on neurovascular function by restoring BBB integrity and NVC
full article: pubmed.ncbi.nlm.nih.gov/4208…
🚨 Does vascular identity matter in stroke?
This new #HotTopic shows that loss of laminin α4 shifts vessels toward a more arterial-like state and worsens stroke outcomes, likely via increased vascular permeability and autotaxin signaling.
discover more 🔗journals.sagepub.com/doi/ful…
Excited to share our latest publication in @_JCBFM demonstrating that targeting cellular senescence mitigates the effects of midlife obesity on neurovascular function by restoring BBB integrity and NVC
full article: pubmed.ncbi.nlm.nih.gov/4208…
🚨 Exercise your way to a healthier brain 🧠💪
New #HotTopic shows cardio isn’t just for the heart: it boosts brain blood flow and oxygen efficiency.
👉Read the study in healthy adults aged 50 🔗 journals.sagepub.com/doi/ful…#BrainHealth#Exercise
🚨 Could CO₂ be a game-changer in #stroke care?
This #HotTopic shows that COâ‚‚ preconditioning before ischemia:
→ ↑ cerebral blood flow
→ ↓ brain damage
→ protects the blood–brain barrier
→ NO added bleeding risk
🔗 Free access (1 month): journals.sagepub.com/doi/ful…
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📢 Tag @JCBFM to boost the visibility of your work and spark discussion.
🔥 Stay up to date with the journal’s latest “Hot Topic” articles: journals.sagepub.com/topic/c…
Neuroinflammation in vascular cognitive impairment and dementia: Insights from clinical biomarkers and experimental models journals.sagepub.com/doi/10.…
🚨 This #HotTopic shows that stroke isn’t just a brain disease: it also reshapes the gut!
After stroke: 🧠→đź¦
→ early gut dysfunction
→ partial recovery in weeks
→ BUT lasting structural & microbiome changes for months
🔗 journals.sagepub.com/doi/ful…#Stroke#GutBrainAxis
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🙏 Many thanks for bringing attention to a JCBFM paper and encouraging open, healthy discussion. Recognizing and citing relevant work is key to moving science forward.
🔗doi.org/10.1177/0271678X2614…
Our editorial on how genomics and multi-omics can accelerate scientific discovery across stroke research and advance new drug discovery; an introduction to an upcoming special issue for @_JCBFM - with excellent review and original articles journals.sagepub.com/doi/epd…