Joined October 2014
- Tweets 604
- Following 376
- Followers 665
- Likes 2,698
75 Photos and videos
Fern Koay 郭 retweeted
Feb 27
We are looking for a Project Manager to facilitate a new program of work centered around a novel CAR T technology that will lead to a phase I trial & development of novel assets. Please see details below for role description and for further details.
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Feb 3
Untangling how γδ T cells kick-start CD8 immunity!
Ever wondered why gamma delta T cells are required for immunity to liver-stage malaria?
Spoiler - they make IL-4!
@TheDohertyInst @NatImmunol
nature.com/articles/s41590-0…
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Fern Koay 郭 retweeted
19 May 2025
Our third webinar from the AUS/APAC region, will feature Nick Gherardin and Sho Yamasaki. Thursday, June 12th at 17:00 AEST (8:00 London, 16:00 Tokyo).
If you'd like to keep up to date, sign up to the mailing list here: cd1mr1.com/cd1-mr1-society
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Fern Koay 郭 retweeted
26 Jan 2025
Our second webinar hosted from USA, will be by Laurent Gapin and Antonia Rotolo.
Thursday, February 6th at 16:00 GMT (8:00 Pacific, 11:00 Eastern, 1:00 Friday Tokyo)
If you haven't join, get updates and link here: cd1mr1.com/cd1-mr1-society
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Fern Koay 郭 retweeted
9 Dec 2024
Role for γδ T cell-derived IL-4 in initiating CD8 T cell immunity to Plasmodium
doi.org/10.1101/2024.12.06.6…
@Lynette_Beattie
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Fern Koay 郭 retweeted
2 Dec 2024
💪 New immunity research published in the Journal of Experimental Medicine highlights how the body keeps its prompt immune response in check. go.unimelb.edu.au/pgk8
Authors: @_fernace, Prof Dale Godfrey, Dr Calvin Xu
@UniMelbMDHS @TheRMH
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Fern Koay 郭 retweeted
26 Nov 2024
Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signaling. New study from Calvin Xu, Dale Godfrey, Hui-Fern Koay @_fernace @TheDohertyInst @UnimelbMDHS and colleagues: hubs.la/Q02YLYGN0
#LymphocyteBiology
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Fern Koay 郭 retweeted
27 Nov 2024
Sharing our latest work @PNASNews
MR1 presents vitamin B6–related compounds for recognition by MR1-reactive T cells
We postulate that tumours' increased metabolism of vit B6 leads to elevated levels of pyridoxal and preferential recognition of tumours by pan-cancer T cells
see 🧵
ALT MR1 presents vitamin B6–related compounds for recognition by MR1-reactive T cells | PNAS https://www.pnas.org/doi/10.1073/pnas.2414792121
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22 Nov 2024
We're incredibly stoked and honoured to have Fabio Grassi's commentary on our paper - this work has built on many of his team's findings and body of work, in the nexus of purinergic control of T cell activation and function! 🌟
19 Nov 2024
Grassi @LaStatale discusses new study by Xu, @_fernace et al (hubs.la/Q02YM3m20) which defines NAD-induced cell death via purinergic P2RX7 receptor in type 1 unconventional T cells, particularly intrahepatic MAIT cells pivotal in liver homeostasis hubs.la/Q02YMplz0
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21 Nov 2024
Sharing our latest work @JExpMed! We've uncovered that P2RX7 regulates unconventional T cells selectively, particularly subsets that co-produce IFN-γ & IL-4. Hoping this helps more discoveries in the role of these innate-like cells, using inhibitors from the P2RX7/ARTC2 field!
19 Nov 2024
In @JExpMed, Xu, @_fernace et al. @TheDohertyInst reveal that the ARTC2–P2RX7 regulatory axis is a key modulator of unconventional T-cell survival, showing how this pathway selectively influences innate-like, IFN-γ and IL-4 co-producing T cells. hubs.la/Q02YMvMt0
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21 Nov 2024
Conceptually, non-peer review'd diagram here: Within T cells at least, integrating thoughts posed by labs of P.Brennan, B.Jabri, perhaps the extent of tissue damage sensitivity could be a hallmark of the ‘T cell-innateness’ theory. tinyurl.com/ycy6dv24
tinyurl.com/bd6kxekk
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21 Nov 2024
Huge thanks to all our collaborators including @LMackayLab @Lynette_Beattie @JeffreyYWMak and those not on here, across @TheFlorey @UQ_News @UniMelbMDHS labs!
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Fern Koay 郭 retweeted
19 Nov 2024
Xu, @_fernace et al. @TheDohertyInst reveal that the ARTC2–P2RX7 regulatory axis is a key modulator of unconventional T-cell survival, showing how this pathway selectively influences innate-like, IFN-γ and IL-4 co-producing T cells. hubs.la/Q02YM2N90
#LymphocyteBiology
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Fern Koay 郭 retweeted
Such an inspiring morning spent celebrating the 2024 @LOrealAustralia @UNESCO Fellows! For 26 years now, L'Oreal have supported talented females across the globe to shape the future of STEM 🙌
@DrMistyJenkins @LeannTilley @_fernace @ProfJennyGraves
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Fern Koay 郭 retweeted
31 Oct 2024
Delighted to share our paper on adipose gd T cells making IL-17 every night for homeostasis, coordinating lipid metabolism after eating @Nature Huge effort by
@Akaron0884 & @BrennethS and the team and collaborators to work this out. Aaron's Tweetorial 👇
nature.com/articles/s41586-0…
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