A good general overview of
#Fluoroquinolone antibiotic toxicity
Fluoroquinolone toxicity -
Dec 16, 2022
article by Dr. Peggy Hung
(Excerpt)
How fluoroquinolones cause severe side effects:
The underlying mechanisms and symptoms include:
Toxicity to musculoskeletal tissues, degradation of collagen, and damage to the cartilage -
This can cause symptoms like joint pain, joint stiffness, tendonitis, and tendon rupture.
Damage to the nerve cells (neuropathy) -
Which can result in numbness, tingling, burning, pain, tremors, changes in sensation (e.g. touch, temperature) in the arms and legs, and dizziness.
Downgrade of GABA-A receptors and cause neurotoxicity -
GABA is responsible for calming and inhibitory effects on our central nervous system. What FQs do is that they bind to GABA receptors but instead of exerting an inhibitory effect, they do the opposite. So they not only compete and prevent the binding of GABA and other molecules like benzodiazepines (medication used to treat anxiety and insomnia) to GABA receptors, but they also induce stimulant effects on the central nervous system. This can result in a series of neuropsychiatric symptoms like anxiety, agitation, insomnia, and seizures.
Other possible symptoms include depression, nightmares, paranoia, confusion, hallucinations, suicidal thoughts, convulsions, and psychosis.
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For the complete article in its entirety, please go here:
drpyhung.com/post/fluoroquin…
Disclaimer: Fluoroquinolone Toxicity Study does not provide medical advice, and all articles and written content are intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Supplements, treatments, and pharmaceutical outcomes can vary greatly between individuals.
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