Postdoc @huiskenlab, developed isotropic and rapid light sheet microscopy. Nature Biotechnology (2025). Read here: nature.com/articles/s41587-0…
Joined June 2011
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Pinned Tweet
14 Nov 2025
🎉 I am very glad to share that our paper on the rapid isotropic light-sheet microscope has just been published in @NatureBiotech.
🔗 Read the full article: nature.com/articles/s41587-0…
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Mostafa Aakhte retweeted
For Nature Biotechnology’s 30th anniversary, our editors look back at a few of their favorite papers published in the past decade go.nature.com/4sWhZs1
rdcu.be/fbCVM
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Mostafa Aakhte retweeted
Mar 5
Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx
Part of sfb1690.uni-goettingen.de/ that studies hearing, vision, and more.
Plus, you can create pretty pictures like the one below :).
ALT A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.
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Mostafa Aakhte retweeted
Jan 11
⚠️ Update: #Iran's internet shutdown is entering its fourth day with connectivity to the outside world remains at just 1% of ordinary levels; at 72 hours, diminished telecoms continue to impact the public's ability to access information and communicate with loved ones ⏱️
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Mostafa Aakhte retweeted
Jan 9
BREAKING: The Iranian anti-regime protesters have practically taken over Iran’s 2nd-largest city Mashhad.
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Mostafa Aakhte retweeted
Jan 9
به تکتک شما که پنجشنبهشب (١٨ دی)، خیابانهای سرتاسر ایران را تسخیر کردید، افتخار میکنم. دیدید که جمعیت انبوه، باعث عقبنشینی نیروهای سرکوب میشود. آنهایی که تردید داشتید، جمعهشب (١٩ دی-ساعت ٨) به دیگر هممیهنان بپیوندید، و جمعیت را بیشتر کنید تا توان سرکوب رژیم از این هم کمتر شود. همچنین از رهبران میدانی دعوت میکنم که تلاش کنند تا مسیرهای مختلف جمعیت به هم برسند و بزرگتر شوند. میدانم که با وجود قطع اینترنت و ارتباطات، خیابانها را رها نخواهید کرد. مطمئن باشید که پیروزی از آن شماست!
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Yes
As soon as we kick you out
Jan 9
God willing, God will bring the feeling of victory to the hearts of all the Iranian people very soon.
Community note
Missing important context:
As of the time this post was written, Iran's government headed by Khamenei shut down the Iranian people's phone and internet lines, in a nationwide blackout coupled with threats to issue death penalties to Iranians protesting the government.
reuters.com/world/middle-e…
bloomberg.com/news/articles/…
dw.com/en/iran-protes…
theguardian.com/world/2026/jan…
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President Trump, this is a serious offer.
We offer you this 4900 acres complex in Tehran as a gift.
Free our country, and you can turn it into a hotel & casino.
It is currently a shrine housing the founder of the Islamic Revolution’s tomb. You can do whatever you want with it
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Mostafa Aakhte retweeted
Jan 9
This is a direct threat to the President of the United States @POTUS.
Khamenei has shut down all means of communication, and is killing Iranians on the streets who are demanding the End of IR, and the Return of Prince @PahlaviReza.
@RapidResponse47
@SecRubio
@WhiteHouse
Jan 9
The US President who judges arrogantly about the whole world should know that tyrants & arrogant rulers of the world, such as Pharaoh, Nimrod, Mohammad Reza [Pahlavi] & other such rulers saw their downfall when they were at the peak of their hubris. He too will fall.
Community note
Ali Khameni is a dictator who has ruled for 37 years. Throughout his tenure, his government has been responsible for several crimes, including human rights abuses against the citizens of Iran, the support for terrorist organizations, and shooting down civilian airliners.
en.wikipedia.org/wiki/Human_rig…
hrw.org/world-report/2…
en.wikipedia.org/wiki/Mahsa_Ami…
en.wikipedia.org/wiki/Ukraine_I…
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Jan 9
The Islamic brutal regime is killing people in Iran.
Internet shut down. Voices silenced. Truth buried.
This is fear clinging to power—not strength.
The world must not look away.
@realDonaldTrump @_FriedrichMerz @bundeskanzler @EmmanuelMacron @EU_Commission #Iran
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Mostafa Aakhte retweeted
14 Nov 2025
Research Briefing: High-speed isotropic light-sheet microscopy nature.com/articles/s41587-0…
rdcu.be/ePWjG
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Mostafa Aakhte retweeted
13 Nov 2025
Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue go.nature.com/4odcS49
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Mostafa Aakhte retweeted
13 Aug 2025
Deeplearning-based #CRISPR DNA integration and editing by @XenoThomasnaert @SLienkamp @UZH_en with lots of #mesoSPIM #lightsheet #Microscopy data (and some taken with the #Schmidt multiimmersion objective prototype!) 🔬nature.com/articles/s41587-0…
12 Aug 2025
Elated to present our study on how AI can improve CRISPR-Cas9 precision! 🎉🧬 Read about it in our press release news.uzh.ch/en/articles/medi… while we prepare a big tweetorial for later this week. @frogwranglers
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Mostafa Aakhte retweeted
30 Jun 2025
Self-organized criticality can occur in cellular systems, but its origins remain unclear. Now it is shown that cytoskeletal criticality is influenced by the F-actin architecture and myosin active stress.
nature.com/articles/s41567-0…
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Mostafa Aakhte retweeted
19 May 2025
We are excited to share our development of a new 10X lens with NA=0.50 over a 7.2 mm FOV and a 35 mm working distance (water), fully corrected from 400-850 nm. This lens will power our upcoming ExA-SPIM "2" and is available for dissemination - please get in touch if interested!
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Mostafa Aakhte retweeted
17 Apr 2025
New review out on imaging 3D cell cultures. Congratulations to Huai-Ching and @jonliu123 on leading this excellent new review! nature.com/articles/s41592-0…
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#ScientificBreakthrough: AI-designed protein targets heart failure mechanism. First demonstration of a new, lab-verified protein designed to target cellular energy depletion in heart failure.
Experimental validation confirms successful synthesis, improved stability, and confirmed ATP binding affinity.
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Mostafa Aakhte retweeted
4 Apr 2025
Sound-sheet microscopy - in this study, we introduce nonlinear sound-sheet microscopy (NSSM), a method to image targeted biological functions across cubic centimeters of opaque living tissue. science.org/doi/10.1126/scie…
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