Assistant Professor, Biomedical Engineering @BME_NUS @NUSingapore | PI, Confinement Mechanobiology Lab @ConfinementLab, Mechanobiology Institute @mbisg
Joined August 2015
- Tweets 615
- Following 447
- Followers 1,442
- Likes 1,749
103 Photos and videos
Pinned Tweet
May 27
Congrats to @nicoleleejw (and other @ConfinementLab co-authors) on her main story coming out this month in @CellReports! Check out this thread if you’re interested in what Nicole discovered on the role #MechanicalMemory plays in facilitating cell migration in #confinement
9 Sep 2025
#Preprint alert! Check out @ConfinementLab’s new research on the role of #mechanical #memory in potentiating confined migration: biorxiv.org/content/10.1101/…
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May 27
Congrats to @nicoleleejw (and other @ConfinementLab co-authors) on her main story coming out this month in @CellReports! Check out this thread if you’re interested in what Nicole discovered on the role #MechanicalMemory plays in facilitating cell migration in #confinement
9 Sep 2025
#Preprint alert! Check out @ConfinementLab’s new research on the role of #mechanical #memory in potentiating confined migration: biorxiv.org/content/10.1101/…
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May 27
Also, since it didn't get selected but I really like the design from @ConfinementLab's Jennifer Marlena, here's our cover art! Bonus points if you can guess my favorite artist... #destijl
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May 27
@nicoleleejw is defending her #PhD in a few weeks and will be on the #postdoc market, so get in touch with her if you are looking for an outstanding #mechanobiologist!
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May 26
Huge congratulations to our Microfab MacGyver Gianluca Grenci for his new position at @UniPadova! As a result-@MBIsg is on the hunt for a new Microfab core facility head. Feel free to get in touch with me or Gianluca with questions! mbi.nus.edu.sg/jobs/seeking-…
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May 18
First international @ConfinementLab retreat on the tropical island of Langkawi (aka Lab-kawi) is in the books! There was plenty to explore for the #beachcrew, #junglecrew, and #culturecrew! Want to join in on the fun as a PhD student or postdoc? Get in touch!
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14 Dec 2025
Congratulations to newly minted Dr. @LY_Sci, Ph.D. #3 from the @ConfinementLab, aka Dr. Kueh Auntie, for her successful defense! If you're wondering what #Kueh has to do with confinement, keep an eye out for Yixuan's upcoming paper!
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This is a great opportunity to do undergraduate research, especially international students!!
14 Dec 2025
Attention #undergrads! Interested in experiencing a summer of #mechanobiology research at @MBIsg ? Apply for our MUST program! We accept students from all around the world, so don't hesitate to reach out for more information!
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14 Dec 2025
Attention #undergrads! Interested in experiencing a summer of #mechanobiology research at @MBIsg ? Apply for our MUST program! We accept students from all around the world, so don't hesitate to reach out for more information!
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Andrew Holle retweeted
11 Sep 2025
@jess_kabigting @Yusuke_Toyama @ahcells showed us the challenges of how immune cells are able to digest and clear large adipocytes (~100um) often found in aged tissue. Multiple smaller macrophages need to infiltrate an ECM shell to reach the dead adipocytes! #MBIMPG2025
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Andrew Holle retweeted
9 Sep 2025
How do cells remember their mechanical environment? Nicole Lee @ahcells @MBIsg identifies transcription factor NFATC2 as a key regulator of mechanical memory – a link between past stiffness and future behaviour such as enhanced migration through confined spaces. #MBIMPG2025
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Andrew Holle retweeted
9 Sep 2025
Day 1, done and dusted! But the party is just getting started with The Hawker Center Mentorship Night at three of Singapore’s most iconic hawker centers – ABC Brickworks, Lau Pa Sat and Newton Food Center. See you there! #MBIMPG2025
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9 Sep 2025
#Preprint alert! Check out @ConfinementLab’s new research on the role of #mechanical #memory in potentiating confined migration: biorxiv.org/content/10.1101/…
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9 Sep 2025
Big picture, we think that interfering with this mechanism to attenuate or even prevent cancer cell #migration in tight spaces holds translational potential. Another example of #confinement helping us gain a better understanding of cell biology in general!
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9 Sep 2025
Bonus- if you happen to be at the @MBIsg #MBIMPG2025 conference this week, @nicoleleejw will be giving a talk on her work TODAY at 5:00 PM!
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