🇨🇦 Rheumatologist, scientist, dad, he/him, advocate for #healthcare, #rheumatology, #research, #osteoarthritis. Tweets my own

Joined March 2011
69 Photos and videos
Tom Appleton retweeted
🚨Standard scRNA-seq often excludes cells with high mitochondrial RNA content (pMT).🚨 Work by Tran et al. investigates how exclusion of high-pMT cells affects the transcriptional landscape of knee OA synovium and explores their role in disease. 🔗sciencedirect.com/science/ar…

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Tom Appleton retweeted
📢 “When we first started to see the big effects of these blockbuster #GLP1 drugs, people were talking about weight loss from Hollywood to regular people’s homes,” said Dr. Tom Appleton @appletonlab. Read the Healio Exclusive @HealioRheum 👇 vist.ly/4tb3a
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Tom Appleton retweeted
15 Jan 2025
🎙️NEW #AroundtheRheum podcast episode! Co-hosts Drs. Daniel Ennis & @Janetbirdope chat with Dr. Sherry Rohekar about the new Canadian Living Guideline for the Management of Axial Spondyloarthritis! You won't want to miss it! Listen now🔈podcasts.apple.com/ca/podcas…
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Oof 😓. 🇦🇺 AUS health demographics often parallels Canada 🇨🇦… not so great outlook. Intl. #osteoarthritis research community: let’s go! 📈
Out now in @TheLancetRheum - our new arthritis projections for Australia @ArthritisAust @Monash_SPHPM @RachelleBuchbin @danielleberko ➡️ 3.11 million people living with OA by 2040 ➡️ almost $10 billion of health system expenditure for OA by 2040
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Well said @ronjune2 this is helpful insight
6 Dec 2024
Wanted to add a bit about this paper...I learned a ton! First, there is some very good OA biomarker work out there, led by the Krauss Lab at Duke. Also, almost 50% of the papers were papermill crap. Written with/exclusively by AI using public data and not contributing...
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A total honour! You will all do great things in, and for the world. Science medicine 💜🩺 🧬
Last week, we had the incredible opportunity to hear from Western MD/PhD alum & @CITAC_ACCFC co-founder Dr. Tom Appleton @appletonlab on all things clinician-scientist (no cap 😎) — from funding research to finding jobs, writing great grants #ABW, & balancing career & family 💡👏
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Rheumy (the bear) and the Rheums! Our new band name! Jk, come see Rheumy at the ⁦@takeapaincheck⁩ booth at #ACR24
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Replying to @jrheum
@ACEJointHealth Love @jrheum A constant in Canadian rheumatology since 1728! 😉🙌🏼 @CarterCartho @Janetbirdope @appletonlab @RheumNow @EsdaileJohn #ACR24 #jrheum
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Should we be striving to prevent STD (synovial tissue damage) in #osteoarthritis trials? 📣
Interesting findings in this month's @OACJournal 🚨 Worse histopathological scores for synovial tissue damage is associated with more pain in late-stage knee OA ➡️ Free to read doi.org/npbv @HollyPhilpott14 @appletonlab @Path_Matt @WOBL_Western ⁩ ⁦
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Inflammation is bad. What if synovial tissue damage is even worse? In our new study, ⁦@HollyPhilpott14⁩ and the #WOREO team discover a link between synovial tissue damage and worse OA pain. ⁦@WOBL_Western⁩ ⁦@westernuBJI⁩ ⁦@WesternUsciencedirect.com/science/ar…

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Fun with the @CanRIO_Tweets team!
Thanks to @NigilHaroon and @CRASCRRheum for sponsoring the members of #Canadian #CanRio ▶️cohort on oncology Pts who have #rheumatic complications from #immune #checkpoint #inhibitors A lovely dinner and #karaoke 🎤 #ICI 🇨🇦 Singing and dancing nearly surpasses research!
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Alright #MedTwitter What’s your differential for knee pain? Let’s do this! ⬇️ #osteoarthritis
3 May 2024
As part of our @oarsinews Early-stage symptomatic knee osteoarthritis (#EsSKOA) initiative: Our goal is to identify common conditions considered in the differential diagnosis of #EsSKOA. Take the survey here: redcap.utoronto.ca/surveys/?… Closes May 20, 2024
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Got data? Join the effort! ⬇️📣
3 May 2024
The Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) Initiative @oarsinewsis seeking datasets for analyses Let us know if you have a dataset with >100 adults with knee symptoms & data on identified candidate items redcap.utoronto.ca/surveys/?…
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Tom Appleton retweeted
3 May 2024
The Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) Initiative @oarsinewsis seeking datasets for analyses Let us know if you have a dataset with >100 adults with knee symptoms & data on identified candidate items redcap.utoronto.ca/surveys/?…
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Go Frank! 🥂
Congratulations to the Distinguished University Professor Dr. Frank Beier. Great lecture and well deserved celebration 👏🏼 @BeierLab @westernuProvost @WesternU @SchulichMedDent @westernuPandP
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Tom Appleton retweeted
Interested in helping the early-stage symptomatic knee #osteoarthritis (#EsSKOA) classification criteria development @OARSInews initiative? Participate in this survey: redcap.utoronto.ca/surveys/?…
Early-stage symptomatic knee #osteoarthritis (#EsSKOA)— an @OARSInews initiative expertly presented by @curious_zan, @Lauren_King_, & @rheum_cat (and expert handling of Q&A!) #OARSI2024
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The #EsSKOA classification criteria initiative is being led by outstanding early career investigators ⁦@curious_zan⁩ ⁦@Lauren_King_⁩ and ⁦@rheum_cat#OARSI2024@OARSI_ECI
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Great discussion and priorities to be set! Add your voice 📣⬇️ #OARSI2024 @OARSInews
Don't miss the inaugural @OARSInews Post-Traumatic OA (PTOA) Discussion Group meeting at #OARSI2024 in Vienna Follow this link for more information & to express your interest (even if you can't attend in person) bit.ly/3U5rBlz
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⁦Tremendously well-deserved! My PhD supervisor and close friend ⁦@BeierLab⁩ is indeed distinguished by his internationally recognized work as a scientist, compassionate leadership, and courage and optimism as a person. Congratulations Frank! 🎉👏🏻 news.westernu.ca/2024/04/dis…
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