Clinical language modeling @ucsf Butte Lab || 🌲

Joined February 2016
36 Photos and videos
Brenda Miao retweeted
Excited to be at #AMIA2024 in SF this week, giving two talks (both today!): ➡️ Evaluating Large Language Models for Drafting ED Discharge Summaries ➡️ Utilizing GPT-4 to determine reasons for missed follow-up colonoscopy following abnormal non-invasive colorectal cancer screening
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Brenda Miao retweeted
#AI is helpful in an ER setting but shouldn't be blindly trusted, UCSF’s Dr. @cykwilliams tells @kron4news. It can help answer exam questions & draft notes—"but it’s not currently designed for situations that call for multiple considerations," he explains. ucsfh.org/3U5bhRF
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Brenda Miao retweeted
Grateful for the opportunity provided by the NAIRR Pilot program! I hope it becomes a permanent program to democratize access to computing resources. Extending thanks to @bmeow19 for helping all through the ideation and writing, and Oksana for helping shape it even further!
21 Sep 2024
WOW! @MadhumitaSushil wins another National Artificial Intelligence Research Resource (NAIRR) pilot award, now bringing @UCSF total to 5 and the @UofCalifornia total to 16! BRAVO! nairrpilot.org/projects/awar…
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Brenda Miao retweeted
21 Sep 2024
WOW! @MadhumitaSushil wins another National Artificial Intelligence Research Resource (NAIRR) pilot award, now bringing @UCSF total to 5 and the @UofCalifornia total to 16! BRAVO! nairrpilot.org/projects/awar…

13 May 2024
35 teams were awarded @NSF @WhiteHouse Natl AI Research Resource NAIRR pilot projects, for access to @DOEScience & NSF advanced computing systems! AMAZING to see three awarded to @UofCalifornia, and TWO at @UCSF including @MadhumitaSushil! CONGRATS! buff.ly/4be3sPQ
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Brenda Miao retweeted
3 Jul 2024
Congrats to @mariebinvignat @bmeow19 @msirota84 @lindseycriswell @UCSFRheum @UCSF_BCHSI and team on our new publication in @JCI_insight on single-cell RNA-seq analysis in rheumatoid arthritis! insight.jci.org/articles/vie…
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Brenda Miao retweeted
20 Jun 2024
And it's out! Congratulations @madhumitasushil and team on our new publication in Journal @AMIAinformatics on comparing multiple LLMs on zero-shot inference and task-specific supervised classification of @UCSF breast cancer pathology reports, including UCSF-BERT! "On tasks where large annotated datasets cannot be easily collected, LLMs can reduce the burden of data labeling" academic.oup.com/jamia/advan…

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Brenda Miao retweeted
4 Jun 2024
If you’re currently having trouble accessing ChatGPT, Claude, or other platforms… you know where to go. You.com systems are alive and well.
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Brenda Miao retweeted
Come by poster 432 to talk to @ardademirci14 about his work with @TravisZack2 applying large language models to identifying discrepancies in assigning performance status! #ai #asco24 @UCSF_BCHSI @UCSFCancer @UCJointCPH
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Brenda Miao retweeted
24 May 2024
I recently had the privilege of presenting some words at the 2024 Graduation Commencement of the @McWilliamsSBMI (thanks for the invite, Dean @JiajieZhang100)! Here is the speech I delivered, if anyone is interested: Dear parents, families, faculty members, staff, and of course the 54 distinguished graduates celebrating with us here, out of the 90 total. You are not just getting a degree today, you have somehow managed to be the very best experts in getting computers to understand humans, and humans to understand computers, in the especially difficult area of biomedicine!  You’ve mastered the art of algorithms and analytics and artificial intelligence. You’re the magicians who turn data into diagnoses, treatment plans, and pathway analyses, and sometimes, even more data! But to be serious, we are privileged to be in this field. We are lucky to be alive when computers are so incredibly powerful and data from protons to patients to planets are so available, and even open access!  It may not seem so, but we are lucky to be able to write grant proposals and get a few of them funded. It is fun and sometimes funny to complain on social media when NIH doesn’t fund the very best grant proposal we’ve ever written. But we are privileged. In most cases, we still get to keep our jobs as much needed informaticians, in academia or industry, when budgets or proposals don’t get funded. Let’s remember how lucky we are all to be here. Today, I really want to communicate my thoughts about duties. I think of four duties we have as informaticians. The first duty is a Duty to help others: especially those we call patients or participants.  The importance of health data has never been stronger for the entire world’s population. It could not be more clear how much of the rest of the world’s education, commerce, transport, exchange, communication, prosperity, and livelihoods all depend on health. And as we’ve seen, the opening and closing of the world for business depends on a daily streams of numbers. Biomedicine, and all the industries that it touches, is already a data-driven business, but let’s not lose the humanity behind it.  And it’s important for all of our organizations to take care of the data, respect it, protect it, but also to use it, to help our patients and families. Respect the data and especially respect those that luckily let us have their data, samples, and measurements. Here’s another way to think about our duty to help others. How many of you were funded on a federal grant? Like a training grant, or your lab principal investigator’s NIH grant? Why do you think the federal government gives out grants to us? I don’t think they just give us money for us to get a great job as a scientist. I think they give us money for us to create jobs too!  When the government says we want to create jobs, how do you think they do it?  We are part of that solution! Look, many of you are looking to get a job either in industry or academia for your next steps. But in your future steps, I am asking you to think about how to create even more jobs and perhaps start more companies! I believe that is a big reason why the government gives us money to pursue our ideas is to empower us to help our communities by creating careers. The second duty is a Duty to the truth: we are strangely in a reproducibility crisis, a false data crisis, and a plagiarism crisis, all at the same time! And we have a lot of competing interests in healthcare. Some of you might end up working at a health care payer. Some of you might end up at a health care provider. IF we are not careful, your AI is going to fight their AI! But go after the big problems! A small solution for a really tough problem is still going to help more than yet another way to analyze the same type of data again and again. And don’t just build a web-site. If you’ve built a computational tool, you are already the best at using it! Use that tool on data, and if you can’t find data, use open public data, and teach the world what you’ve found, not just the mechanics of your tools. I do very much believe that the vast majority of scientists and engineers do well and mean well. Don’t fall into traps like believing your career depends on H-index or citation counts. These are made up games. Did Marie Curie or Albert Einstein even care what their citation count was? i’m guessing not. The third duty is a Duty to yourself in the end, you are responsible for your health, physical and mental. They say we only get one body, so watch out for it. it’s easy to spend hours in our profession sitting in front of a computer. Please remember to seek out the outside and walk, yes, even though it is impressively and oppressively humid here in Houston! Finally, the fourth duty is a Duty to those who got you here: They’ve invested time, money, effort, and in most cases love, and we owe them our thanks. They are counting on you to change the world.  I would love for the graduates to stand and thank those that are here and beyond, for getting us here, all together for this moment. We’re in a time when we, in general, are incredibly privileged to be here with our education and our potential, but we are admittedly living in complicated times, where even universities around us are trying to reestablish their roles in education, public discourse, or even as the town square.  I do encourage you to try to seek out the goodness in the news, in your science and engineering, in your neighbors, and in your colleagues. We are all in this together, we get one big chance at it, let’s all try to do some good for this world. Thank you.
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23 May 2024
It’s been a fun journey working in the clinical LLM space 🙂 Come check out my PhD thesis seminar @ucsf Byers Auditorium Thursday 2pm or message me for a zoom link! @UCSF_BCHSI
22 May 2024
PhD exit talk by Brenda Miao @bmeow19 happening on Thursday 2pm @UCSF Byers Auditorium, with reception to follow! Join us in celebrating Brenda's PhD work! Uncovering Strategies For Personalized Treatment Selection Using Large Language Models Healthcare data has never been so accessible to patients and physicians, from smartphones and other remote monitoring devices to improved Electronic Medical Record (#EMR) data access. Despite this increasing ubiquity, insights from these data are often only captured in medical notes and other complex, spare, and unstructured real-world data. Here, we develop methods to use large language models (#LLM) to identify points of actionable insights from real-world data for both digital and pharmaceutical therapeutics. These new methods allow us to take an unprecedented look at the conversations, decisions, and medical expertise captured in millions of clinical notes and other real-world text data. #AI
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Brenda Miao retweeted
Excited to be at @AMIAinformatics #CIC24 in Minneapolis this week alongside an incredible @UCSFHospitals @UCSF_DOCIT team, giving a talk on how #LLMs can be used to identify barriers to optimal patient care #qualityimprovement Join us at 9.30 am CT Wednesday in Marquette 2&3!
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Brenda Miao retweeted
7 May 2024
The potential for LLM #AI to do accurate triage in the emergency department for patient acuity @JAMANetworkOpen @atulbutte jamanetwork.com/journals/jam…
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Brenda Miao retweeted
Thrilled to announce our latest paper "Use of a Large Language Model to Assess Clinical Acuity of Adults in the Emergency Department" published today in @JAMANetworkOpen @TravisZack2 @bmeow19 @madhumitasushil Michelle Wang @AaronKornblith @atulbutte
LLMs may be able to accurately identify higher acuity patient presentation when given pairs of presenting histories extracted from patients’ first ED documentation. ja.ma/3y3M55E @atulbutte
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Brenda Miao retweeted
LLMs may be able to accurately identify higher acuity patient presentation when given pairs of presenting histories extracted from patients’ first ED documentation. ja.ma/3y3M55E @atulbutte

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Brenda Miao retweeted
7 May 2024
Out today in @JAMANetworkOpen! Cross-sectional study w/ 10 000 pairs of ED visits, @OpenAI GPT accurately identified the patient w/ higher acuity when given pairs of deidentified presenting histories. Work by @cykwilliams @TravisZack2 @bmeow19 @madhumitasushil Michelle Wang @AaronKornblith.
LLMs may be able to accurately identify higher acuity patient presentation when given pairs of presenting histories extracted from patients’ first ED documentation. ja.ma/3y3M55E @atulbutte
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Brenda Miao retweeted
5 May 2024
Check out @UCSF_BCHSI @ImmPortDB poster B941 by @SanchitaB and Reuben Sarwal on Leveraging GPT-4 for Enhanced Cell-Type Deconvolution in Immunological Research, today between 11:30 am and 12:45 pm! #AAI2024 #AI #opendata
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