Products with extensive/rich UIs lots of sliders, switches, menus, with no scripting support, and built on opaque, custom, binary formats are ngmi in the era of heavy human AI collaboration.
If an LLM can't read the underlying representations and manipulate them and all of the related settings via scripting, then it also can't co-pilot your product with existing professionals and it doesn't allow vibe coding for the 100X more aspiring prosumers.
Example high risk (binary objects/artifacts, no text DSL): every Adobe product, DAWs, CAD/3D
Example medium-high risk (already partially text scriptable): Blender, Unity
Example medium-low risk (mostly but not entirely text already, some automation/plugins ecosystem): Excel
Example low risk (already just all text, lucky!): IDEs like VS Code, Figma, Jupyter, Obsidian, ...
AIs will get better and better at human UIUX (Operator and friends), but I suspect the products that attempt to exclusively wait for this future without trying to meet the technology halfway where it is today are not going to have a good time.