This is the official Twitter account of DANIO-CODE, an international collaborative effort that aims to annotate the functional elements of the zebrafish genome.
ALT black and white line genome browser track lines forming different developmental stages of zebrafish in the style of the album cover unknown pleasure by joy division.
ALT List of research highlights:
Highlights
• 1,802 samples, 38 stages, 38 labs, 19 assay types
• precise TSS, alternative promoters, promoter architecture classes
• developmental TF activity-qualified TFBS prediction
• >140,000 cis-regulatory elements, single-cell based cell-type specificity
• new visualisation of epigenetic profiles, new functional subclasses
• H3K27ac-rich ensembles support early expression of developmental factors and long-range regulation
• vertebrate epigenomic landscape conservation by anchored projection tool
• vertebrate regulatory element equivalence without sequence conservation
DANIO-CODE is proud to share our findings and a huge multi-genomics resource on the regulatory elements in the development of #zebrafish. We analyzed 1,802 previously (un)published sequencing data sets across 38 developing stages and 21 assay types. (1/n) biorxiv.org/content/10.1101/…
ALT Screenshot of the title and authors of the paper.
ALT bubble chart of all available datasets per zebrafish stage
The deep learning model integrated information about enhancer activity (like ChIP-seq data, histone modification data, known motif sequences and actual vertebrate data from zebrafish @daniocode. We found patterns of transcription factor binding site enrichment 8/n
A regulatory network of Sox and Six transcription factors initiate a cell fate transformation during hearing regeneration in adult zebrafish dlvr.it/SX2xBS
ALT black and white line genome browser track lines forming different developmental stages of zebrafish in the style of the album cover unknown pleasure by joy division.
ALT List of research highlights:
Highlights
• 1,802 samples, 38 stages, 38 labs, 19 assay types
• precise TSS, alternative promoters, promoter architecture classes
• developmental TF activity-qualified TFBS prediction
• >140,000 cis-regulatory elements, single-cell based cell-type specificity
• new visualisation of epigenetic profiles, new functional subclasses
• H3K27ac-rich ensembles support early expression of developmental factors and long-range regulation
• vertebrate epigenomic landscape conservation by anchored projection tool
• vertebrate regulatory element equivalence without sequence conservation
ALT black and white line genome browser track lines forming different developmental stages of zebrafish in the style of the album cover unknown pleasure by joy division.
ALT List of research highlights:
Highlights
• 1,802 samples, 38 stages, 38 labs, 19 assay types
• precise TSS, alternative promoters, promoter architecture classes
• developmental TF activity-qualified TFBS prediction
• >140,000 cis-regulatory elements, single-cell based cell-type specificity
• new visualisation of epigenetic profiles, new functional subclasses
• H3K27ac-rich ensembles support early expression of developmental factors and long-range regulation
• vertebrate epigenomic landscape conservation by anchored projection tool
• vertebrate regulatory element equivalence without sequence conservation
DANIO-CODE is proud to share our findings and a huge multi-genomics resource on the regulatory elements in the development of #zebrafish. We analyzed 1,802 previously (un)published sequencing data sets across 38 developing stages and 21 assay types. (1/n) biorxiv.org/content/10.1101/…
ALT Screenshot of the title and authors of the paper.
ALT bubble chart of all available datasets per zebrafish stage