Transforming #genomics with #deeplearning
Joined September 2014
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23 Oct 2023
We're at the #OTS23 Meeting this week -- excited to share updates on our application of #AI to the discovery and development of #oligonucleotide and #RNA therapeutics.
Stop by to learn more at the following 4 posters.
oligotherapeutics.org/2023-a…
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23 Oct 2023
3/4: P041: BigRNA: A Large Neural Network Enabling Accurate Oligonucleotide Design and Variant Effect Predictions
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23 Oct 2023
4/4: P104: DeepMirBind: A Deep Learning Approach for MicroRNA Target Site Prediction and Design of Upregulation Oligonucleotides
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Deep Genomics retweeted
27 Sep 2023
Découvrez ce nouveau travail étonnant du sponsor bronze de Vecteur @deepgenomics et du cofondateur de Vecteur, Brendan Frey. Comme indiqué ci-dessous, l'équipe a développé le premier modèle de base pour les thérapies ARN 👇
27 Sep 2023
We are thrilled to share our manuscript ‘An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics’ as a preprint! 🧵
biorxiv.org/content/10.1101/…
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Deep Genomics retweeted
27 Sep 2023
Check out this amazing new work from Vector Bronze Sponsor @deepgenomics & Vector co-founder Brendan Frey. As outlined below the team developed the first foundation model for RNA therapeutics 👇
27 Sep 2023
We are thrilled to share our manuscript ‘An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics’ as a preprint! 🧵
biorxiv.org/content/10.1101/…
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Deep Genomics retweeted
27 Sep 2023
The first foundation #AI model for RNA
biorxiv.org/content/10.1101/…
Predicting protein and microRNA binding sites, tissue-specific expression, variants -> gene expression and splicing
@deepgenomics @frey_brendan and colleagues
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27 Sep 2023
We are thrilled to share our manuscript ‘An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics’ as a preprint! 🧵
biorxiv.org/content/10.1101/…
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27 Sep 2023
15/16 Here it’s important to have accurate predictions to lower the number of drugs screened. We analyzed variants in ClinVar that are amenable to this approach.
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27 Sep 2023
16/16 We hope that our model BigRNA, and more RNA foundation models like it, will continue to transform the fields of disease variant interpretation and personalized therapeutics
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