💭Striving to understand how cells communicate with their environment 🔍Focusing on TGF-beta in development and cancer @thecrick 🧑🔬Run by lab members
Joined December 2018
- Tweets 134
- Following 248
- Followers 622
- Likes 372
20 Photos and videos
Here's a round-up of recent job adverts on the Node!
▪️Research technician: @CigliolaLab @GabKardon
▪️PhD: @KarenJLiu @Dariloops @smadar_de @RealFany
▪️Postdoc: @CigliolaLab @deMendoza_Alex @devsiglab @LabSpagnoli
Browse our jobs board:
thenode.biologists.com/jobs/
ALT Screenshot of the Node jobs board
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Hill Lab retweeted
5 Dec 2023
👀What's that? Flies 🪰 on the cover of @Dev_Cell ? (Fish 🐟 too) Congrats @WilcocksonScott on getting the cover, and yet another reason to plug Scott's work! Check out the stocks in @flystocks!
cell.com/issue/S1534-5807(22…
ALT https://www.cell.com/issue/S1534-5807(22)X0024-5#fullCover
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Hill Lab retweeted
4 Dec 2023
First Postdoc paper, first 🦓🐟 paper, first journal cover! 🥳
🎶On the fourth day of Christmas, Dev Cell gave to me: An improved Erk biosensor that detects oscillatory Erk dynamics driven by mitotic erasure during early development🎶
cell.com/developmenta...
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Hill Lab retweeted
29 Nov 2023
Caroline Hill @devsiglab has been a JCS editor since 2020 and handles articles relating to #developmentalsignalling and chromatin/epigenetics. Have a manuscript focussing on one of these topics? Send it our way! bit.ly/3SEPVux
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30 Oct 2023
We are looking for 3 #postdoc fellows to join us!! Investigating embryonic patterning, signalling dynamics and buffering stochastic cell fate induction in #zebrafish and #hESCs @TheCrick @devsiglab
eur03.safelinks.protection.o…
eur03.safelinks.protection.o…
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Hill Lab retweeted
14 Sep 2023
Online now: An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development dlvr.it/Sw5sVH
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Hill Lab retweeted
14 Sep 2023
Want to study ERK dynamics in real time? There's an improved tool to do just that!
@WilcocksonScott and @devsiglab's paper is out! We made the fly version of Scott's new construct. Read about it here, and get the fly stocks @flystocks (#95284-8)!
authors.elsevier.com/sd/arti…
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Hill Lab retweeted
14 Sep 2023
For all your Erk-related needs, we have the reporter for you! And it’s out now!
Big thanks to Luca, Pablo, @AmoyelLab and @devsiglab
cell.com/developmental-cell/…
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Hill Lab retweeted
23 Aug 2023
Read about the latest in TGFβ signalling in cell fate regulation: from embryonic development through to tissue homeostasis and disease @devsiglab
go.nature.com/3P7Fwp2
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Hill Lab retweeted
23 Aug 2023
Our latest #NRMCBReview is now online!
Louise Richardson, @WilcocksonScott and Luca Guglielmi (now @MRC_LMB) from the Hill lab (@devsiglab @thecrick) discuss TGF-beta signalling in cell fate regulation:
🔗go.nature.com/3P7Fwp2
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8 Jun 2023
A great blog post summarising our recent adventures imaging ERK signalling live! Thanks for highlighting our preprint!
7 Jun 2023
Just like this ERK reporter, a new UDS Writing Club post is LIVE! Will Anderson describes great work by @WilcocksonScott in the Hill lab @devsiglab 🙌 kwrogers-lab.org/uds-writing…
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Hill Lab retweeted
7 Jun 2023
Submissions in Journal of Cell Science are handled by expert Academic Editors. From cell signalling, cell migration, cell adhesion, and cell division, through to cancer cell biology, immunology, mechanobiology and more, our team of research-active academics covers a range of topics and is supported by an international Editorial Advisory Board. We also show a strong commitment at first decision, with over 95% of invited revisions being accepted for publication. Find out more at bit.ly/3Wyg1PE
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Hill Lab retweeted
21 Dec 2022
Want Erk-cellent representation of Erk signalling dynamics?
@WilcocksonScott and colleagues from @AmoyelLab & @devsiglab explore an improved biosensor that faithfully reports Erk activity without being impacted by Cdk1.
First #preLight from @Kobayashi1S: prelights.biologists.com/hig…
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11 Nov 2022
We’re very excited to present work headed by @WilcocksonScott in collab with @AmoyelLab on an Erk biosensor and signalling dynamics during early development. See 🧵 for the preprint in brief
biorxiv.org/content/10.1101/…
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11 Nov 2022
Finally, we observe that Erk activity is highly dynamic: as cells approach mitosis, they rapidly (~2mins) extinguish pErk which introduces periods of inactivity, a process we refer to as mitotic erasure.
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11 Nov 2022
For anyone interested in Erk signalling dynamics, particularly if your cells of interest are proliferative, please get in contact for plasmids or fish. Drosophila lines are already available at @flystocks (#95284-95288)
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Erk-cited (excited) about the new work from our @devsiglab colleagues !!!
7 Nov 2022
New from my @TheCrick colleagues in @devsiglab lab
Improved Erk-Kinase biosensor w/o off target response to Cdk1
Shows Erk activity transiently extinguished during mitosis, which introduces signaling heterogeneity into an asynchronously dividing tissue
biorxiv.org/content/10.1101/…
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