Finally someone with sense

Robots in China are doing it all now, even dancing on stage like pros. Here Unitree robots doing Webster flips and are performing at Chinese-American singer Wang Leehom’s concert in Chengdu.

🚨 Mental illness has just been traced to a single gene for the first time. For decades, mental illnesses like schizophrenia were believed to arise from the complex interplay of numerous genes and environmental factors. Now, a groundbreaking study has identified the first single gene capable of triggering psychiatric disorders entirely on its own. Researchers have pinpointed GRIN2A as this rare culprit. In some individuals carrying specific damaging variants of the gene, severe psychiatric conditions – including schizophrenia-like symptoms – can emerge as early as childhood, rather than the typical onset in late adolescence or early adulthood. Perhaps most strikingly, several patients exhibited purely psychiatric symptoms with no trace of the seizures, intellectual disability, or developmental delays that were previously considered hallmarks of GRIN2A-related disorders. This finding dramatically reframes our understanding of how genetic mutations can lead to mental illness. GRIN2A encodes part of the brain’s NMDA receptors, which are critical for communication between neurons. When the gene is faulty, it throws this signaling system into disarray. Encouragingly, some affected individuals showed clear improvement when given L-serine, an inexpensive amino acid supplement that helps restore NMDA receptor function. Though still in its early stages, the discovery raises the prospect of genuinely precision-based treatments for certain forms of mental illness – therapies that correct the root genetic cause rather than merely managing symptoms. The results come from the world’s largest registry of GRIN2A patients and represent more than ten years of close collaboration between neurologists, psychiatrists, and geneticists across the globe. ["GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy." Molecular Psychiatry, 2025]

What can't Lionel Messi do 😅

This is a really stupid account which post old research as new and simplifies it as sensationalism to get more clicks

If black, fight back If brown, lay down If white, good night

Hey @grok, who was the most famous person to visit my profile? It doesn't need to be a mutual, don't tag them, just say who it was

Everyone is waiting for #GTA6 meanwhile me waiting for the next Dan brown novel.

Here's my conversation with astrophysicist @JannaLevin all about black holes, information paradox, general relativity, quantum mechanics, gravitational waves, wormholes, alien civilization, and more. It's here on X in full, and is up everywhere else too (see comment). Timestamps: 0:00 - Episode highlight 2:03 - Introduction 3:03 - Black holes 10:37 - Formation of black holes 21:28 - Oppenheimer and the Atomic Bomb 27:50 - Inside the black hole 40:53 - Supermassive black holes 44:22 - Physics of spacetime 47:25 - General relativity 52:56 - Gravity 1:09:29 - Information paradox 1:17:59 - Fuzzballs & soft hair 1:21:10 - ER = EPR 1:27:49 - Firewall 1:36:41 - Extra dimensions 1:39:06 - Aliens 1:54:42 - Wormholes 2:05:40 - Dark matter and dark energy 2:15:43 - Gravitational waves 2:27:51 - Alan Turing and Kurt Godel 2:40:05 - Grigori Perelman, Andrew Wiles, and Terence Tao 2:46:40 - Art and science 2:56:19 - The biggest mystery

This one is FUCKING WILD. Literally. Ben Lamm and his team are Colossal Biosciences have brought back the Dire Wolf. Fascinating conversation available now on @spotify open.spotify.com/episode/6G5…

Proposed Immediate Rule Changes for UWW: 1.) 1kg second Day Weight Allowance. 2.) Weigh-ins pushed from 8:30am to 10:30am. 3.) Forfeit will occur in future finals if opposing finalist misses weight. 4.) After a semifinal victory, both finalists’ medals are secured even if weight is missed on Day 2. Gold can only be won by a wrestler who makes weight on the second day. 5.) Give Vinesh the Silver medal.

Here's my conversation with Sara Walker (@Sara_Imari), a physicist and astrobiologist. We discuss how life emerged on Earth and in the Universe. She wrote a new book on just this topic, go pre-order it. This was a mind-blowing and super fun conversation. It's here on X in full, and is up on YouTube, Spotify, and everywhere else. Links in comment. Timestamps: 0:00 - Introduction 1:07 - Definition of life 21:45 - Time and space 32:26 - Technosphere 36:51 - Theory of everything 45:32 - Origin of life 1:07:10 - Assembly theory 1:23:24 - Aliens 1:35:14 - Great Perceptual Filter 1:39:12 - Fashion 1:43:14 - Beauty 1:49:35 - Language 1:56:16 - Computation 2:06:03 - Consciousness 2:14:55 - Artificial life 2:38:48 - Free will 2:45:32 - Why anything exists

Messi is one of one. 🐐

⚽️ Messi's brace, including his first penalty goal in 16 months, takes him to 2nd in the MLS scoring charts, just 1 behind leader Cristian Arango ✨ 🥇 C Arango 8⃣⚽️ 🥈 L Messi 7⃣⚽️📈 🥉 L Suarez 6⃣⚽️ Messi has missed 4 of Miami's 10 league games this season!

Conversations with in-game characters are getting more real! Presenting our research project, NEO NPCs, a new kind of NPC that uses generative AI to really talk to you! Discover how our team of writers and developers are coming together in this exciting experiment: ubi.li/PDyOG

STRAIGHT HANDS ARE BACK ON THE SOULS SERIES THANK YOU ELDEN RING

In the Land of Shadow, Miquella awaits the return of his promised Lord. Pre-order #ELDENRING Shadow of the Erdtree: bnent.eu/EldenRing-SOTE

SORA can animate images pretty amazingly. Prompt: "In an ornate, historical hall, a massive tidal wave peaks and begins to crash. Two surfers, seizing the moment, skillfully navigate the face of the wave." #SoraAI