MD-PhD, researcher in ADHD, Psychiatry resident @PittPsychiatry

Joined February 2020
3 Photos and videos
18 Apr 2025
Very happy to see this paper out!
New paper alert🚨 Our new study led by @dtleffa & @guilhermepovala published @alzdemjournals links genetic risk for ADHD to more severe dementia. Check here: alz-journals.onlinelibrary.w…
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Douglas Leffa retweeted
Looking forward to the Pascoal team’s presentations at this Saturday’s #AIC pre-conference! @NeuroimagingPIA @ISTAART @alzassociation Check out our line-up:
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Douglas Leffa retweeted
Congratulations to @BellaverBruna for receiving the Publication of the Year Award from the Biofluid Based Biomarkers @ISTAART Professional Interest Area at PIA day, for her recent paper in Nature Medicine! #AAIC24
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Douglas Leffa retweeted
Very proud to share this one! Here we showed transcriptomic similarities and differences between three AD animal models and EOAD and LOAD. Thank you all to collaborators involved @giovannacollar @erzimmer @mvlourenco @aslfricardo @TharickAPascoal @pedrorosaneto
🚨ONLINE NOW! In our new article led by @BellaverBruna and #DeBastiani published in @iScience_CP, we took advantage of comparative medicine tools to investigate molecular core similarities and differences among AD mouse models and EOAD and LOAD individuals tinyurl.com/3fj8b8tb
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11 Jan 2024
Amazing work by the great @jpfsouza33 !
Out now in Neurobiology of Aging! In this new article, we demonstrated that vascular risk burden & AD pathophysiology jointly accelerate neurodegeneration and cognitive decline in CU individuals @erzimmer @ufrgsnoticias @ppgbioq @CAPES_Oficial @TharickAPascoal @LabPascoal
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Douglas Leffa retweeted
Please join us in welcoming new faculty members Bruna Bellaver, PhD (Research Assistant Professor of Psychiatry), and Pamela Lukasewicz Ferreira, PhD (Research Assistant Professor of Psychiatry)! bit.ly/3SeYaNE
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Douglas Leffa retweeted
Research from Pitt's School of Medicine may hold the key to understanding Alzheimer's progression. Read more about this groundbreaking study. pittmag.pitt.edu/news/advanc…
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Douglas Leffa retweeted
A link between #ADHD and #Alzheimers disease has been suspected for some time, and now two separate #research studies have shown a #connection. Find out more āž”ļø bit.ly/3KrQnHD.
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Douglas Leffa retweeted
What an amazing experience at #AAIC23! Thanks a lot for the @alzassociation @ISTAART for the opportunity to share our work from @LabPascoal šŸ‡ŗšŸ‡ø & @zimmerneurolab šŸ‡§šŸ‡·. Already excited to see you all again in Philly #AAIC24 🧠
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Amazing @jpfsouza33 !
Congrats to our PhD student @jpfsouza33 for receiving the Prof. Gilberto Schwartsmann Award for publishing the best paper in 2022-23 (rdcu.be/dhOJk) among the medical students at @ufrgsnoticias! Huge team effort led by JoĆ£o together with @LabPascoal & @zimmerneurolab šŸ‘
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Any program would be lucky to have you!
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Douglas Leffa retweeted
We are happy that @dtleffa's work linking ADHD with Alzheimer's is being featured in numerous TV broadcasts across the country, reaching millions of Americans wgem.com/2023/07/24/brain-co…
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Douglas Leffa retweeted
We thank the @alzassociation and are very proud of our postdocs @gbnegrini and @SarahAbbas52 awarded with the AA Research and Clinical fellowships, respectively. They will address important gaps in tau PET harmonization and the use of inflammation biomarkers in trials. Congrats!!
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Douglas Leffa retweeted
What a fantastic talk by @guilhermepovala at #AIC23, where he discussed the impact of microglial activation on brain atrophy in preclinical AD. #AAIC2023 @alzassociation @ISTAART
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Douglas Leffa retweeted
During the coffe break don’t miss the opportunity to check the beautiful poster of @FrancieliRohden where she evaluated the association between astrocyte reactivity and synaptic distinction!! #AAIC2023 @alzassociation
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Douglas Leffa retweeted
Fantastic presentation by @dtleffa where she showed that the individuals with ADHD and cognitive impairment may have a more severe disease phenotype. #AAIC2023
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29 May 2023
Amazing work by @BellaverBruna !!
Replying to @LabPascoal
By assessing more than 1,000 CU participants, we observed that plasma p-tau181 increases as a function of Aβ only in individuals that present positive astrocyte reactivity biomarker signature (Ast ). The presence of both A /Ast showed a large magnitude of effect on p-tau levels.
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Amazing work from @jpfsouza33 ! You will shape the Alzheimer’s field, my friend!
Our latest work is out in @ScienceAdvances🚨! Using multiple PET radiotracers, we found clinical evidence that APOEε4 contributes to microglial activation in early Braak regions, which is further associated with AD progression 🧠. Link: science.org/doi/10.1126/scia…
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Douglas Leffa retweeted
This morning @BellaverBruna presented her results on how kidney function impacts plasma p-tau levels, mainly in cognitively unimpaired individuals. If you missed it, her presentation is also available on-demand! @adpdnet #ADPD2023 #adpd23
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Douglas Leffa retweeted
@BellaverBruna work "BLOOD-BRAIN BARRIER PERMEABILITY IMPACTS THE PERFORMANCE OF PLASMA AMYLOID-B" can be found in the poster hall by the number 329.#ADPD2023 @adpdnet
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