@edilytics profile picture
Edilytics @edilytics

Precision analytics for genome editing. Creators of CRISPResso2.

Joined February 2019
  • Tweets 254
  • Following 128
  • Followers 93
3 Photos and videos
Edilytics@edilytics
7 Apr 2025
Thanks for using CRISPResso!
Profluent
@ProfluentBio
4 Apr 2025
Scientific sharing fuels progress. Our friends at @Edilytics developed CRISPResso, an open-source CRISPR analysis tool built for researchers. Together with OpenCRISPR-1, the future of customizable gene editing is more accessible than ever. Check it out: edilytics.com/#crispresso
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Edilytics@edilytics
7 Feb 2025
We are thrilled to be a part of @BioUtah!
BioUtah@BioUtah
7 Feb 2025
🎉 Welcome, @Edilytics, to @BioUtah! Their flagship product, CRISPResso, is the industry standard for analyzing genome editing events from NGS data, supporting diverse editing modalities with 1,650 citations in academia & industry. 🔗 Learn more: edilytics.com
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Edilytics@edilytics
23 Aug 2024
We are excited to attend @CSHL's CRISPR Frontiers conference next week. Let us know if you are going and we can talk all things genome editing analysis!
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Edilytics@edilytics
22 Nov 2023
Congratulations to @CRISPRTX and @VertexPharma for UK approval of Casgevy to treat sickle-cell disease and β-thalassaemia. Hope to continue to see more therapies brought closer to the clinic! nature.com/articles/d41586-0…

UK first to approve CRISPR treatment for diseases: what you need to know

Nature - The landmark decision could transform the treatment of sickle-cell disease and β-thalassaemia — but the technology is expensive.

nature.com
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Edilytics@edilytics
24 Oct 2023
Excellent talk @grunewaju! #esgct (Thanks for using CRISPResso in your slides and work)
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Edilytics@edilytics
20 Oct 2023
Happy #WorldCRISPRDay! To celebrate we would like to announce the launch of crispresso.com. Join us in celebration by analyzing your #CRISPR experiment, happy analyzing!
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Edilytics@edilytics
20 Oct 2023
Our team is excited to be at the @ESGCT congress next week! If you are going we would love to meet you in person, feel free to reach out so that we can connect.
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Edilytics@edilytics
2 Oct 2023
Fascinating protocol from Changtian Pan @PCT71158462 & Yiping Qi constructing CRISPR-Combo systems for speed breeding of genome-edited plants. Thanks for using #CRISPResso in your analysis! nature.com/articles/s41596-0…

CRISPR-Combo–mediated orthogonal genome editing and transcriptional activation for plant breeding

Nature Protocols - This CRISPR-Combo system enables efficient multiplexed orthogonal genome editing and transcriptional activation in plants. Here, the use of CRISPR-Combo is demonstrated for speed...

nature.com
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Edilytics@edilytics
11 Sep 2023
Congratulations to Bestas et al. on their paper illustrating a new nuclease with lower off-targets and translocations. Thanks for using CRISPResso! nature.com/articles/s41467-0…

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

Nature Communications - SpCas9 unintended editing is a major concern. Here the authors report an off-target method using Duplex Sequencing with increased sensitivity for Cas9 mutation detection;...

nature.com
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Edilytics@edilytics
16 Aug 2023
Excited to be at @CSHL's #CRISPR Frontier meeting this week. If you are there too, send a DM and would love to connect!
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Edilytics@edilytics
13 Jun 2023
Congratulations to Alex Reed, Benjamin Cravatt, @jfernandobazan, et al. on their groundbreaking paper utilizing #CRISPR technology to show the role of TMEM164 in ferroptosis. Thanks for using #crispresso2 nature.com/articles/s41589-0…
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Edilytics@edilytics
24 Apr 2023
Congratulations to Mohr, Damas, Gudmand-Høyer, et al. on their groundbreaking @ACSSynBio paper utilizing #CRISPR technology for precise genetic engineering. Thank you for using #crispresso2! pubs.acs.org/doi/10.1021/acs…

The CRISPR-Cas12a Platform for Accurate Genome Editing, Gene Disruption, and Efficient Transgene...

CRISPR-Cas12a nucleases have expanded the toolbox for targeted genome engineering in a broad range of organisms. Here, using a high-throughput engineering approach, we explored the potential of a...

pubs.acs.org
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Edilytics@edilytics
24 Apr 2023
Congrats to Kaiqin She, Yi Liu, Qinyu Zhao, et al. on their recent paper on correcting mutations and phenotypes in retinal degenerative mice using split prime editing. Thanks for using #crispresso2 doi.org/10.1038/s41392-022-0…

Dual-AAV split prime editor corrects the mutation and phenotype in mice with inherited retinal...

Signal Transduction and Targeted Therapy - Dual-AAV split prime editor corrects the mutation and phenotype in mice with inherited retinal degeneration

nature.com
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Edilytics@edilytics
24 Apr 2023
Congrats to Fuminori Tanihara, Maki Hiratat, et al. on their recent paper using electroporation and #CRISPR to cause an INS point mutation in pigs! Thanks for using #crispresso2! doi.org/10.3389/fcell.2023.8…

Frontiers | Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9...

Just one amino acid at the carboxy-terminus of the B chain distinguishes human insulin from porcine insulin. By introducing a precise point mutation into the...

frontiersin.org
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Edilytics@edilytics
11 Mar 2023
Congrats to @kaisa_pakari @WittbrodtLab @_ThomThum_ et al. on their recent paper on de novo PAM generation to reach initially inaccessible target sites for base editing . Thanks for using #crispresso2 journals.biologists.com/dev/…

De novo PAM generation to reach initially inaccessible target sites for base editing

Summary: A combinatorial and sequential one-shot approach termed ‘inception’ is a twist on base editing that allows initially inaccessible nucleotides to be reached.

journals.biologists.com
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Edilytics@edilytics
10 Mar 2023
Congrats to Li, et al. on their recent paper developing prime editing. Thanks for using #crispresso2! doi.org/10.1038/s41467-023-3…

Development of a versatile nuclease prime editor with upgraded precision

Nature Communications - Strategies to improve the specificity of nuclease-based prime editor (PEn) are needed. Here the authors report a 53BP1-inhibitory ubiquitin variant-assisted PEn platform...

nature.com
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Edilytics@edilytics
10 Mar 2023
Congrats to Jin, et al. on their recent paper on how to circumvent barriers to in vivo #CRISPR use. Thanks for using #crispresso2! genomebiology.biomedcentral.…

Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and...

Genome Biology - CRISPR-based toolkits have dramatically increased the ease of genome and epigenome editing. SpCas9 is the most widely used nuclease. However, the difficulty of delivering SpCas9...

link.springer.com
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Edilytics@edilytics
9 Mar 2023
Congrats to Liao, Chen, Hsiao, Jiang, et al. on their recent paper using #CRISPR base editing to potentially treat inherited monogenic blood disorders! Thanks for using #crispresso2! doi.org/10.1038/s41467-022-3…

Therapeutic adenine base editing of human hematopoietic stem cells

Nature Communications - Here, Liao and colleagues apply adenine base editor ABE8e and its PAM-less variant ABE8e-SpRY to β-thalassemia patient hematopoietic stem cells in the form of...

nature.com
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Edilytics@edilytics
8 Mar 2023
Congrats to @nicopmat #AhmedAllam et al. on their recent paper using high-throughput screen to analyze #primeediting outcomes. Thanks for using #crispresso2 doi.org/10.1038/s41587-022-0…
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Edilytics retweeted
Prime Medicine@PrimeMedicine
2 Mar 2023
We're leading the next generation of gene editing and are excited to make our Twitter debut. Follow us to stay in the loop on all things $PRME.
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