Lab of Daniel Flaherty, Ph.D. Associate Professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University.
Joined August 2015
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180 Photos and videos
29 Aug 2025
New paper out today from @Katrina_Holly98 and Prabhakara Rao Tharra on their work on development of bacterial carbonic anhydrase inhibitors against vancomycin-resistant Enterococci. They produced an analog with oral efficacy rescuing mice in a septicemic peritonitis model.
Bacterial carbonic anhydrase inhibitors with improved PK and efficacy in VRE septicemia mouse model. #JMedChem @flahertylab @DrugDiscoveryPU @Purdue_MCMP
go.acs.org/d4V
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Flaherty Lab retweeted
Design strategy from @FlahertyLab yields improved solubility for AC1 inhibitors with in vivo efficacy in rat model for inflammatory pain. #JMedChem
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25 Oct 2024
Our postdoc position is still open! #malaria #ubiquitin #proteasome #protein degradation #UPR #artemisinin #resistance #drug resistance
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15 Oct 2024
This project in collab with Dr. Val Watts and @Purdue_MCMP grad student @tiffany_summerr has gone from hit identification to through two manuscripts. The current scaffold had solubility liabilities and we took an approach to break up the molecular planarity to improve solubility
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New ethoxzolamide analogs from @FlahertyLab show improved PK properties and efficacy in mouse model for gonococcal infection. #JMedChem
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Covalent UCHL1 inhibitor with crystal structure and anti-metastatic properties from @FlahertyLab @WendtLab_Cancer @KesslerlabOx
Read in #JMedChem here ➡ go.acs.org/8LT
ALT abstract image from linked article
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19 Feb 2024
I am honored to receive this title. Thank you to Chip and Jane Rutledge and to @purduepharmacy for the support!
19 Feb 2024
Chip and Jane Rutledge have a history of impactful service to Purdue. The duo shares a passion for supporting early career faculty that inspired them to endow a new professorship. Daniel Flaherty is the inaugural recipient. Full story: loom.ly/kLB-aqY #pharmacysgiantleap
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28 Sep 2023
Our department is hiring two positions. One in chemical biology and one in translational neuroscience. Come join a fantastic department with great colleagues!
27 Sep 2023
@Purdue_MCMP is hiring for Faculty Positions in Translational Neuroscience and Chemical Biology careers.purdue.edu/job-invit…
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27 Sep 2023
@Purdue_MCMP is hiring for Faculty Positions in Translational Neuroscience and Chemical Biology careers.purdue.edu/job-invit…
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25 Aug 2023
New paper from my group and @nglab_malaria on the identification of covalent inhibitors against P. falciparum UCHL3. Keep an eye on this work in the future from our groups 😉 @Purdue_MCMP @DrugDiscoveryPU @UNMC_PathMicro
sciencedirect.com/science/ar…
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