nephrologist & clin. scientist; ultrasound enthousiast; vasc. biology&kidney disease; #FOAMed; 👩🏻⚕️👩🏻💻👩🏻🔬🔬🎻🏔️🏝️🚴♀️🏃🏻♀️views = own //🦋sfleig
Joined October 2018
- Tweets 984
- Following 953
- Followers 588
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64 Photos and videos
Pinned Tweet
20 Apr 2022
PAPER ALERT! :-)
Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures -
nature.com/articles/s41467-0…
rdcu.be/cLIL1 out today in @NatureComms .
Thank you to all coauthors!
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5 Apr 2025
Cold-induced hypertension via sympathetic nerve activation 👇
3 Apr 2025
RESEARCH ARTICLE: Progressive Increase in Renal Sympathetic Nerve Activity Induced by Cold Exposure
ahajrnls.org/3YgKt2J
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5 Apr 2025
Next up Laetitia Préau from @lenoblelab on novel organotypical angiogenic cell types determining neural vascularization
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5 Apr 2025
And Haaglim Cho from MPI Bad Nauheim on EC insulin resistance induced by adrenomedullin mediating obesity-associated diabetes
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Susanne Fleig retweeted
5 Mar 2025
Now online in @NDTsocial
The evolving spectrum of kidney amyloidosis
🧐 Advances in diagnosis, typing and treatment
▶️academic.oup.com/ndt/article…
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17 Jan 2025
Open call for abstract submission and applications for the GfMVB Emerging Scientist award and the Aletta Jacobs Award session at pcvb2025.de in Frankfurt, April 3-5, 2025!
#vascularbiology
#cardiovascular
#EVBO
#GfMVB
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Susanne Fleig retweeted
18 Dec 2024
1/13) We are thrilled to share our new paper published in @NatureCommunications (shorturl.at/M5ie4) that systematically compares scRNA multiplexing methods and develops a new genetic multiplexing workflow SoupLadle.
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Susanne Fleig retweeted
12 Dec 2024
Thrilled to see the final version of our venous #thrombosis study on procoagulant platelets on the Cover of this week‘s @BloodJournal issue 🩸🫶
@nicolai_leo @LMU_Uniklinikum @dzhk_germany @EKFStiftung @dfg_public
Props to our PhD student Maité, who took this beautiful image!
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Susanne Fleig retweeted
9 Dec 2024
In this editorial, the authors argue that a study by Winkelman et al. puts into question the traditional dietary recommendation to avoid whole grains in CKD and underscores the importance of diet quality in CKD, by pointing out the potential negative effects of plant-source UPFs on cardiovascular and kidney outcomes. bit.ly/CJASN0595
@fleig_s
ALT Photo by Rachael Gorjestani on Unsplash.
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Susanne Fleig retweeted
5 Dec 2024
Happy to share our new paper @NatureComms led by @KonradHoeft @BleckwehlTore @sikandhayat. Label-free single-cell RNA multiplexing leveraging genetic variability. nature.com/articles/s41467-0… 🔥🔥👇👇 Tweetorial will follow
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Susanne Fleig retweeted
20 Nov 2024
For all those interested in vascularizing organoids, check out this great paper from Maggiore et al on their inducible vascularized kidney organoid model and my accompanying commentary!
kidney-international.org/art…
kidney-international.org/art…
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Susanne Fleig retweeted
19 Nov 2024
Is Fast not Furious?
In cohort studies reviewed by a giant in electrolyte research, rapid correction of severe hyponatremia is associated with better rather than worse outcome
@MarcusSaemann @dgfn_ev @AKronbichler @hswapnil @Julie_Celine @nervensystemck
jamanetwork.com/journals/jam…
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Susanne Fleig retweeted
12 Nov 2024
Patient Education: Creative Ways to Add Flavor to Meals Without the Salt by @windycityRD and ChatCPT
jrnjournal.org/article/S1051…
@MarcusSaemann @gregorymmarcus @BruceNeal1 @dgfn_ev @fleig_s @oegnephro @luisbeckdasilva @JustinEzekowitz
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Susanne Fleig retweeted
Chronische Nierenkrankheit (#CKD) ist die 7. häufigste Todesursache bei #Frauen weltweit🌍. Eine neue Studie zeigt: Prävalenz um 2,10 % gestiegen📈, Sterblichkeit um 3,39 %. Besonders betroffen: Frauen ab 70. #Nierengesundheit #Prävention Link zur Studie: tinyurl.com/yn8ztyjn
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Landmark revisit
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
Notch, a vessel-maturation signal, transcriptionally activates CPT1a & #FattyAcidOxidation during #EndothelialCell quiescence
FAO-fed TCA cycle serves as a main source of NADPH (instead of ATP) in quiescent EC😁
EC CPT1a KO⏫LPS-induced endothelial ROS & inflammation
Etoxomir CPT1i⏬EC barrier function
@JoannaKalucka @CarmelietLab @Cell_Metabolism 2018
cell.com/cell-metabolism/ful…
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Susanne Fleig retweeted
Very happy to have contributed to the review on intestinal lymphatics @NatRevGastroHep!
New online! Transport functions of intestinal lymphatic vessels go.nature.com/3C8MA0i
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Susanne Fleig retweeted
3 Nov 2024
Limiting sugar before age 3 protects against diseases later in life science.org/doi/10.1126/scie…
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Susanne Fleig retweeted
2 Nov 2024
Awaiting @Dan_Fuster's interventional SWEET STONE trial: Here comes more epidemiological data that SGLT-2 may substantially lower the burden of nephrolithiasis - here studied in patients with prevalent stone disease
@natalie_mccor @dgfn_ev @MarcusSaemann
bmj.com/content/387/bmj-2024…
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Susanne Fleig retweeted
Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient: Cell cell.com/cell/fulltext/S0092…
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Susanne Fleig retweeted
31 Oct 2024
A new prospective study finds that the angiogenic proteins sFlt-1 and PlGF may predict and improve the diagnostic accuracy for preterm preeclampsia among patients with CKD @placentaMD
ahajrnls.org/4frX7Ck
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