Wayne ~~ ~Jupyter Distinguished Contributor~ ~ ~ fomightez.github.io ~ ~ ~ ~ ~ ~ I run Proteopedia's social media too ~~ ~He/His

Joined September 2012
12 Photos and videos
Wayne retweeted
Project Jupyter is thrilled to share the news about the Jupyter Foundation! #jupyter #jupyterfoundation #opensource
Millions of researchers, scientists, and engineers rely on @ProjectJupyter 📓 Today, the LF is proud to announce the launch of the Jupyter Foundation to support Project Jupyter’s software, standards and services for interactive computing.  🔗hubs.la/Q02YCFV00 #OpenSource
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Wayne retweeted
This is super cool: a full Python app and LLM running in the browser at @py_cafe
1 Oct 2024
Now that LLMs are able to run entirely on client side, I ported over my matplotlib tweaker app and made a few upgrades! Try it over at PyCafe; no API key needed! py.cafe/ahuang11/chat-with-p…
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Wayne retweeted
How does the human #ribosome machinery select an open reading frame on mRNA for translation? Check out our #cryoEM work @NatureSMB: rdcu.be/dUbMg Thanks to all involved - most of all first author @V_Petrychenko and our collaborators from the Rodnina lab @mpi_nat. 1/5
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Wayne retweeted
First structure of a H/ACA snoRNP acting in ribosome synthesis. In a great collaboration with the Hurt lab, we provide a detailed structural and biochemical view of the snR30 snoRNP guiding local 18S rRNA subdomain folding. 👇👇👇
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Wayne retweeted
31 Jul 2024
We're thrilled to share an update about our continued collaboration with @developmentseed on the @NASA Visualization, Exploration and Data Analysis (VEDA) platform! See how we've made it easier for researchers to explore large geospatial datasets 🌍 2i2c.org/blog/2024/veda-devs…

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Wayne retweeted
29 Jul 2024
🥳 Exciting news! You can now experiment with free-threaded Python! 🐍 This major change to CPython allows running multiple threads in parallel for better performance on modern CPUs. Check out Quansight Labs' blog to learn more and get started! 👀 buff.ly/3LIRwdV #python

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Wayne retweeted
The Animation Lab is hiring! We're looking for a software developer for an exciting new project creating intuitive tools for molecular animation. Experience with Python req'd and Blender preferred. Please forward to any interested folks! employment.utah.edu/salt-lak…

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Wayne retweeted
I am excited to share this story led by Yujing Cheng and Siwen Wang (not on X) in @CellCellPress which describes a new function for a small nucleolar RNA (snoRNA) in senescence and ribosome biogenesis. Read on for a brief 🧵1/ cell.com/cell/fulltext/S0092…
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YeastMine is closing July 15 due to ongoing funding cuts. For more info: community.alliancegenome.org… #yeast
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Wayne retweeted
Did you see the bridge RNA papers yesterday? Bacterial transposons promote programmable, RNA-guided DNA recombination. Remarkably, we found that the recombinase was co-opted in archaea and eukaryotes for widspread RNA-guided RNA modification, an essential function in humans!
23 Jun 2024
New preprint: In a fun collaboration with the @SternbergLab, we reveal the evolutionary origin of eukaryotic RNA-guided RNA modification (Nop5 and Prp31) in recently characterized bacterial IS110-family transposons. biorxiv.org/content/10.1101/…
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25 Jun 2024
"In this first map of pseudouridine modifications for C. elegans, we find that they largely reside in coding sequences and that the number of genes with this modification increases with age."
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Wayne retweeted
It was a pleasure presenting at my first @Sca_DS.AI #SummerSchool! I spoke about #LLMs for #BioImageAnalysis, including best-practices for prompt-engineering, LLM fine-tuning, RAGs and benchmarking. 🔬💻🚀🔓 Slides #openaccess: zenodo.org/records/12518075
After a quick lunch, @haesleinhuepf shared insights on using large language models for quantitative bio-image analysis. His talk highlighted the role of prompt engineering in solving common bio-image tasks. #ScaDSAISummerSchool24 #AppliedAI
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Wayne retweeted
🎉 Great news for the #GIS and #Jupyter communities! The @ESA is funding a project by @QuantStack and @simula_research to bring collaborative editing to GIS workflows in JupyterLab. Let's explore new ways of working with geospatial data! 🚀 blog.jupyter.org/jupytergis-…
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Wayne retweeted
11 Jun 2024
Here is another fun one over on @py_cafe ☕️ Protein residue coloring in ipymolstar is now super fast with the latest PDBeMolstar version. Makes for very responsive protein viewer apps! And supports dark mode 😎
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Wayne retweeted
Super excited to announce the pre-release of @py_cafe 🎉 py.cafe is a platform that lets you create, run, edit, and share Python (web) applications directly in your browser. No installation is needed—just a single click, and it runs! #Python #pyodide 🧵👇🏻

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Wayne retweeted
That's two RNA 3D structure modules: one is a four-way junction loop and another is a long-range helix-helix interface, but can you spot the difference?🧐 Find out which is which in our recent preprint on RNA tertiary motif search and their isostericity: doi.org/10.1101/2024.05.31.5…
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Wayne retweeted
Figeno, my visualization tool for genomics🎨🧬, is now published in Bioinformatics! doi.org/10.1093/bioinformati… It can generate publication-quality figures for sequencing data along genomic coordinates: bigwig, HiC, @nanopore data with base modifications, and WGS with CNAs and SVs.
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Wayne retweeted
NEW preprint: 1,154 #yeast genomes🧬 from yeast reveal that faster-evolving lineages experienced higher rates of #gene losses, particularly in gene families related to mRNA splicing, carbohydrate metabolism, and #cell division. The importance of evolution by loss is immense!
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