Ophthopedia Update: Development of diagnostic criteria for Behcets uveitis in a Chinese population dlvr.it/TSzF1L #Ophthalmology #Ophthotwitter #BJO

In Behcets, GLP1 showed a reduction in NETosis through suppression of ROS and the inflammasome.

ละชั้นก็ต้องมานั่งอ่าน guideline Behcets 2025 ให้มัน โอ๊ย

Tomorrow, May 20, is International #BehcetsDisease Awareness Day, and @behcets_usa has everything you need to learn about this rare form of #vasculitis, connect with others, and make an impact—including a webinar tomorrow with @VasculitisFound and a virtual charity walk on Saturday. Read their NORD Guest Blog: rarediseases.org/guest-blog-… #Behcets

Differentials : Proctocolitis herpes simplex virus Behcets

Behcets is a form of vasculitis. I would not expect it to form granules/nodules. @DrKamleshDarji1 could you add something?

Behcets disease - mouth ulcer , joint pain

🧠 Rheumatology MCQ Oral ulcers genital ulcers uveitis Now CVST Next best step? A Steroids B Anticoagulation C Cyclophosphamide D Antibiotics #Rheumatology #Behcets #MedEd @docakx @IhabFathiSulima

What a heartbreaking thread. My healthy 18 yr old daughter has developed POTS. Her dad died of a vascular is (Behcets) and I am so grateful she is tuned in to her body - I hope she takes care of herself.

Grok identified Behcets for me before the drs did.

Great thread 👇 We (rheumatologist) usually see lot of referrals for recurrent Mucositis Most of them have recieved multiple oral vitamins and paste and oral steroids atleast What I have found in our clinic Systematic disease patients often have ma my other clues, which is often easy to elicit, start asking. For eg an SLE patient with palatal ulcer may have many other clues like other rash / female sex / youngish age / Arthralgias / leukopenia Also remember that not all differentials can be proven by blood tests Eg oral lichen Planus or behcets or a malignancy or Crohn’s disease Chronic alcohol and smoking are really significant perpetrators in many Iron deficiency is single most important vitamin probably after b12 which needs good dosing or parental infusion - 7 out of 10 patients referred to us improve with iron. They are often referred because doctors often fail to recognise or treat iron deficiency with or without anemia adequately Recurrent Apthous stomatitis though often invoked by us, there are very few patients who are really refractory. We had one such patient with hepatitis b and under treatment. Had to give regular infliximab and after 2 years evolved to behcets with occurrence of genital ulcers. Hla b51 was negative and there was no other clear semiology to suggest Behcets. Also recieved at-least 10 other drugs before infliximab including colchicine, dapsone, thalidomide, etc. So even if we think of differentials, diseases may take time to evolve. Lastly in rheumatology we see lot of sjogren disease with oral Sicca. Their mucosa is often red and inflamed and under recognition often leads to unnecessary blame on methotrexate / deficiencies / sulfasalazine and they suffer. Timely understanding / use of antifungals for superadded candid infection and use of drugs like oral pilocarpine, salivary substitutes can really be helpful.

Behçet’s 2025 — decode in 60 seconds — 🧠 WHAT CHANGED Organ > disease label Phenotype-driven Rx Early biologics (not last line) — 🩺 MUCOSA (oral/genital/skin) Colchicine → base Apremilast/AZA if needed 🚫 Don’t overkill — 👁 EYE = CLOCK IS TICKING Posterior uveitis = emergency AZA / Anti-TNF early Delay → blindness — 🧠 BRAIN ≠ BODY RULES Parenchymal → steroids AZA/CYC 🚫 No cyclosporine Think aggressive — 🩸 VESSELS THINK DIFFERENT Clot = inflammation IS > anticoag Venous > arterial Aneurysm = danger — 🍽 GUT (IBD mimic) Steroids → AZA / Anti-TNF Treat like inflammatory ulcer disease — 💉 BIOLOGICS RESET TIMELINE Anti-TNF = frontline in severe Not “after everything fails” — 💊 STEROID PHILOSOPHY Use fast Exit faster Avoid chronic — 🔁 DISEASE IS NOT STATIC Phenotype shifts Rx must evolve — 🚨 RED FLAGS = ACT FAST Eye pain Neuro signs Hemoptysis — ⚡ CLINICAL CODE Right organ Right timing Right intensity — 📄 DOI: doi.org/10.1016/j.ard.2026.0… — #Behcets #Rheumatology #Vasculitis #MedTwitter #RheumTwitter #Immunology #EULAR #ClinicalPearls

Literature says most common cause for mobile hypopyon is Behcets disease. Second comes HLAB27 associated uveitis. But in practice number of cases of HLAB27> Behcets

Behcets disease

Our latest iteration of the Behçets living guideline, co-produced with BAD, is available to read in Rheumatology! 🗺️ Make use of the accessibility map to learn what is new & what has changed in this 2nd, living iteration bit.ly/4azIFaG @RheumJnl #Behcets #guideline

Open-label experience with upadacitinib in 27 Behcets pts (median 36 yrs) w/ median BDCAF 4 (2–7). At 6 mos overall response seen in 23/27 (85%) (16 CRs, 7 PRs) w/ signif reductions in BDCAF, CRP, ESR, & steroid dose by week 24. 3 pts relapsed during F/U buff.ly/AnHsAEc

We closed with a Behçet’s multi-system symposium featuring Robert Moots (#Rheumatology), Ian Coulson (#Dermatology) Emma Morgan (Oral Medicine), and myself covering the ophthalmic impacts of this disease, highlighting the importance of true MDT care in a complex disease #Behcets

Behcets

🔎 The image shows: • Recurrent oral aphthous ulcers (canker sores) • Uveitis • Genital ulcers • Erythema nodosum This classic constellation = ✅ Behçet’s Disease ⸻ 💡 Key Features of Behçet’s disease: •Recurrent oral ulcers (mandatory for diagnosis) •Genital ulcers •Uveitis (can cause vision loss) •Skin lesions (erythema nodosum, pseudofolliculitis) •Pathergy positivity •Can cause thrombosis & CNS involvement 🧠 Think: Young patient oral ulcers genital ulcers eye involvement ⸻ If this was an exam question → Diagnosis: Behçet’s syndrome #Rheumatology #Dermatology #Uveitis #Behcets #MedicineMadness

تعرف على اعراض #مرض_بهجت: وأعراضه المتنوعة وكيف يمكن التعامل معه طبياً #dailymedicalinfo #Behcets dailymedicalinfo.com/view-di…